SCI225 Pathophysiology Weeks 9–14 Quiz Questions with Verified Answers,
2026/2027 – Practice Questions with Answers
A patient diagnosed with multiple myeloma reports severe pain. This pain can be attributed to:
neuropathic infiltrations.
destruction of bone tissue.
tissue hypoxia.
accumulation of toxic proteins. - (answer)destruction of bone tissue
Multiple myeloma is a B-cell cancer characterized by the proliferation of malignant plasma cells that
infiltrate the bone marrow and aggregate into tumor masses throughout the skeletal system; thus, the
pain is related to bone destruction, not neuropathic infiltrations, tissue hypoxia, or accumulation of toxic
proteins.
A 67-year-old male was diagnosed with polycythemia vera (PV) but refused treatment. His condition is at
risk for converting to:
chronic lymphocytic leukemia.
Burkitt lymphoma.
multiple myeloma.
acute myeloid leukemia. - (answer)Acute myeloid leukemia
A significant potential outcome of PV is the conversion to acute myeloid leukemia (AML), occurring
spontaneously in 10% of individuals and generally being resistant to conventional therapy. Neither
chronic lymphocytic leukemia, Burkitt lymphoma, nor multiple myeloma is a significant outcome of PV.
A 68-year-old is admitted to the emergency department with a diagnosis of polycythemia vera (PV). A
nurse realizes the patient's symptoms are mainly the result of:
a decreased erythrocyte count.
,SCI225 Pathophysiology Weeks 9–14 Quiz Questions with Verified Answers,
2026/2027 – Practice Questions with Answers
rapid blood flow to the major organs.
increased blood viscosity.
vessel injury. - (answer)increased blood viscosity.
The symptoms of PV are due to increased blood viscosity, the erythrocyte count is elevated, there will be
decreased blood flow to tissues and organs but vessel injury does not occur.
A 5 year old was diagnosed with normocytic-normochromic anemia. Which type of anemia does the
nurse suspect the patient has?
Sideroblastic
Hemolytic
Pernicious
Iron deficiency - (answer)Hemolytic
Hemolytic anemia is an example of normocytic-normochromic anemia. Sideroblastic anemia is an
example of microcytic hypochromic anemia. Pernicious anemia is an example of a macrocytic anemia.
Iron deficiency anemia is an example of microcytic hypochromic anemia.
The people from which country have the lowest risk for Hodgkin lymphoma?
United States
Japan
Denmark
Netherlands - (answer)Japan
Japan has the lowest rate of Hodgkin lymphoma. The United States, the Netherlands, and Denmark have
among the highest rates.
, SCI225 Pathophysiology Weeks 9–14 Quiz Questions with Verified Answers,
2026/2027 – Practice Questions with Answers
After initial compensation, what hemodynamic change should the nurse monitor for in a patient who
has a reduction in the number of circulating erythrocytes?
Increased viscosity of blood
Decreased cardiac output
Altered coagulation
Hyperdynamic circulatory state - (answer)Hyperdynamic circulatory state
After initial compensation, the blood flows faster and more turbulently than normal blood, causing a
hyperdynamic circulatory state. Blood viscosity decreases rather than increases. Cardiac output
increases. Alteration in coagulation does not occur.
Which type of sickle cell crisis occurs only in young children?
Hyperhemolytic crisis
Vaso-occlusive crisis
Aplastic crisis
Sequestration crisis - (answer)Sequestration crisis
Sequestration occurs when large amounts of blood become acutely pooled in the liver and spleen. This
type of crisis is seen only in a young child. Hyperhemolytic, vaso-occlusive, and aplastic crises are not age
specific.
Which major symptom indicates to the nurse that patient diagnosed with sickle cell anemia is
experiencing a vaso-occlusive crisis?
Peripheral edema
Pain
2026/2027 – Practice Questions with Answers
A patient diagnosed with multiple myeloma reports severe pain. This pain can be attributed to:
neuropathic infiltrations.
destruction of bone tissue.
tissue hypoxia.
accumulation of toxic proteins. - (answer)destruction of bone tissue
Multiple myeloma is a B-cell cancer characterized by the proliferation of malignant plasma cells that
infiltrate the bone marrow and aggregate into tumor masses throughout the skeletal system; thus, the
pain is related to bone destruction, not neuropathic infiltrations, tissue hypoxia, or accumulation of toxic
proteins.
A 67-year-old male was diagnosed with polycythemia vera (PV) but refused treatment. His condition is at
risk for converting to:
chronic lymphocytic leukemia.
Burkitt lymphoma.
multiple myeloma.
acute myeloid leukemia. - (answer)Acute myeloid leukemia
A significant potential outcome of PV is the conversion to acute myeloid leukemia (AML), occurring
spontaneously in 10% of individuals and generally being resistant to conventional therapy. Neither
chronic lymphocytic leukemia, Burkitt lymphoma, nor multiple myeloma is a significant outcome of PV.
A 68-year-old is admitted to the emergency department with a diagnosis of polycythemia vera (PV). A
nurse realizes the patient's symptoms are mainly the result of:
a decreased erythrocyte count.
,SCI225 Pathophysiology Weeks 9–14 Quiz Questions with Verified Answers,
2026/2027 – Practice Questions with Answers
rapid blood flow to the major organs.
increased blood viscosity.
vessel injury. - (answer)increased blood viscosity.
The symptoms of PV are due to increased blood viscosity, the erythrocyte count is elevated, there will be
decreased blood flow to tissues and organs but vessel injury does not occur.
A 5 year old was diagnosed with normocytic-normochromic anemia. Which type of anemia does the
nurse suspect the patient has?
Sideroblastic
Hemolytic
Pernicious
Iron deficiency - (answer)Hemolytic
Hemolytic anemia is an example of normocytic-normochromic anemia. Sideroblastic anemia is an
example of microcytic hypochromic anemia. Pernicious anemia is an example of a macrocytic anemia.
Iron deficiency anemia is an example of microcytic hypochromic anemia.
The people from which country have the lowest risk for Hodgkin lymphoma?
United States
Japan
Denmark
Netherlands - (answer)Japan
Japan has the lowest rate of Hodgkin lymphoma. The United States, the Netherlands, and Denmark have
among the highest rates.
, SCI225 Pathophysiology Weeks 9–14 Quiz Questions with Verified Answers,
2026/2027 – Practice Questions with Answers
After initial compensation, what hemodynamic change should the nurse monitor for in a patient who
has a reduction in the number of circulating erythrocytes?
Increased viscosity of blood
Decreased cardiac output
Altered coagulation
Hyperdynamic circulatory state - (answer)Hyperdynamic circulatory state
After initial compensation, the blood flows faster and more turbulently than normal blood, causing a
hyperdynamic circulatory state. Blood viscosity decreases rather than increases. Cardiac output
increases. Alteration in coagulation does not occur.
Which type of sickle cell crisis occurs only in young children?
Hyperhemolytic crisis
Vaso-occlusive crisis
Aplastic crisis
Sequestration crisis - (answer)Sequestration crisis
Sequestration occurs when large amounts of blood become acutely pooled in the liver and spleen. This
type of crisis is seen only in a young child. Hyperhemolytic, vaso-occlusive, and aplastic crises are not age
specific.
Which major symptom indicates to the nurse that patient diagnosed with sickle cell anemia is
experiencing a vaso-occlusive crisis?
Peripheral edema
Pain
