ADVANCED PATHOPHYSIOLOGY UTMB
5355 COMPREHENSIVE TEST BANK FULLY
SOLVED QUESTIONS AND SOLUTIONS
●● Neurotransmitter Receptor Hypothesis linked to depression
Answer: A deficiency of monoamine neurotransmitters at neuronal
synapses.
●● Antidepressants increase
Answer: Neuronal synaptic levels of monoamine neurotransmitters.
●● if you have more receptors than neurotransmitters
Answer: Neurotransmitters do not have time to re-charge thus, they do
not function properly.
●● Hypothalamic-Pituitary-Adrenal (HPA) System Dysregulation
Answer: HPA system dysregulation with excessive glucocorticoid
secretion is found in a large percentage of people suffering from major
depression.
●● Patho of Alzheimer's includes - plaque formation, presence of --,
with decreased levels of -
,Answer: Amyloid B, neurofibrillary tangles, acetylcholine these disrupt
impulse transmission
●● neurofibrillary tangles
Answer: are a deformation of the structure that carries nutrients to
neurons of the brain.
●● Decreased levels of choline acetyl transferase and acetylcholine is
associated with
Answer: Memory loss
●● Most common cause of dementia
Answer: Alzheimer's disease fatal 5-10 years
●● Characteristics of Alzheimer's
Answer: Loss of memory, language , inability to learn new things,
dysfunction, delusions, cannot perform ADLs, majorly effects social life
●● Parkinson's Disease is
Answer: Chronic motor progressive neuro-degenerative known as a
shaking palsy
●● Parkinson's disease is associated with
, Answer: basal ganglia dysfunction and atrophy of neurons in the
substantia nigra that produce dopamine;
●● Characteristics of Parkinson's disease
Answer: Tremors at rest, rigidity, bradykinesia, muscular rigidity and
postural abnormalities.
●● 2 Main Categories of CVA
Answer: Hemorrhagic and Ischemic
●● Hemorrhagic CVA
Answer: Blood produces inflammatory reaction, swelling, displaces
brain tissue and increases ICP
●● 2 types of hemorrhagic stroke
Answer: Intracerebral and subarachnoid
●● Intracerebral Hemorrhage
Answer: Blood vessel leaks directly into brain tissue
●● Subarachnoid hemorrhage
5355 COMPREHENSIVE TEST BANK FULLY
SOLVED QUESTIONS AND SOLUTIONS
●● Neurotransmitter Receptor Hypothesis linked to depression
Answer: A deficiency of monoamine neurotransmitters at neuronal
synapses.
●● Antidepressants increase
Answer: Neuronal synaptic levels of monoamine neurotransmitters.
●● if you have more receptors than neurotransmitters
Answer: Neurotransmitters do not have time to re-charge thus, they do
not function properly.
●● Hypothalamic-Pituitary-Adrenal (HPA) System Dysregulation
Answer: HPA system dysregulation with excessive glucocorticoid
secretion is found in a large percentage of people suffering from major
depression.
●● Patho of Alzheimer's includes - plaque formation, presence of --,
with decreased levels of -
,Answer: Amyloid B, neurofibrillary tangles, acetylcholine these disrupt
impulse transmission
●● neurofibrillary tangles
Answer: are a deformation of the structure that carries nutrients to
neurons of the brain.
●● Decreased levels of choline acetyl transferase and acetylcholine is
associated with
Answer: Memory loss
●● Most common cause of dementia
Answer: Alzheimer's disease fatal 5-10 years
●● Characteristics of Alzheimer's
Answer: Loss of memory, language , inability to learn new things,
dysfunction, delusions, cannot perform ADLs, majorly effects social life
●● Parkinson's Disease is
Answer: Chronic motor progressive neuro-degenerative known as a
shaking palsy
●● Parkinson's disease is associated with
, Answer: basal ganglia dysfunction and atrophy of neurons in the
substantia nigra that produce dopamine;
●● Characteristics of Parkinson's disease
Answer: Tremors at rest, rigidity, bradykinesia, muscular rigidity and
postural abnormalities.
●● 2 Main Categories of CVA
Answer: Hemorrhagic and Ischemic
●● Hemorrhagic CVA
Answer: Blood produces inflammatory reaction, swelling, displaces
brain tissue and increases ICP
●● 2 types of hemorrhagic stroke
Answer: Intracerebral and subarachnoid
●● Intracerebral Hemorrhage
Answer: Blood vessel leaks directly into brain tissue
●● Subarachnoid hemorrhage
