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NSG 318 Final Exam 2026 | Practice Questions, Verified Answers & Detailed Rationales Study Guide

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Prepare for the NSG 318 Final Exam with a comprehensive review resource featuring practice questions, verified answers, and detailed rationales. Strengthen your understanding of key nursing concepts, clinical judgment, patient assessment, safety, prioritization, interventions, and evidence-based care. Designed to support focused studying, knowledge review, and final exam preparation.

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NSG 318 Final Exam
QUESTIONS AND CORRECT ANSWERS
(VERIFIED ANSWERS) PLUS RATIONALES
acquired resistance - ANS✔✔-type of resistance that is caused by prior exposure to an antibiotic.
this can cause an antibiotic to not be effective as it once was for a certain bacteria
Acyclovir (Zovarix) - ANS✔✔-antiviral drug used for the treatment of herpes simplex virus and
varicella
important to increase fluids
phlebitis (check site before and throughout therapy), increased bleeding time
nephrotoxic
Amoxicillin - ANS✔✔-penicillin that is commonly used for otitis media, tonsilitis, and urinary
tract infections
broad-spectrum
monitor urinary output (if less than 30mL/hr, decrease the dose)
tongue/tooth discoloration
superinfection - vaginitis
anaphylactic reaction - ANS✔✔-a reaction to a drug that may begin with shortness of breath and
can lead to vascular collapse, laryngeal edema, bronchospasms, and cardiac arrest.
antacids - ANS✔✔-OTC drugs that should not be taken at the same time as azithromycin
(Zithromax) or levofloxacin (Levaquin)
Azithromycin (Zithromax) - ANS✔✔-antibiotic that inhibits the steps of protein synthesis and is
used for bacterial conjuctivitis, STIs, and skin infections, NOT UTIs works well for those who
are allergic to penicillin/cephalosporin
1 hr before/2 hr after meals and with water
C diff, tinnitus, photosensitivity
broad spectrum antibiotic - ANS✔✔-effective against gram-positive and gram-negative bacteria
BUN, CR, liver enzymes - ANS✔✔-labs needed before giving antibiotics to determine the
ability to metabolize and excrete the drug
Ceftriaxone (Rocephin) - ANS✔✔-broad spectrum antibiotic that is used for OM, meningitis,
and surgical infection prophylaxis that have a disulfiram-like reaction
Cephalosporins - ANS✔✔-if a client is allergic to penicillin they can also be allergic to this
classification of drug
disulfiram like reaction
superinfection: stomatitis
hepatotoxic
clostridium difficile - ANS✔✔-superinfection
multiple episodes of watery, diarrhea that may be bloody, abdominal cramping, and a possible
increased temperature
disulfiram-like reaction - ANS✔✔-a reaction that a client may have with metronidazide (Flagyl)
or ceftriaxone and drinking alcohol
doxycycline - ANS✔✔-antibiotic that is used to treat acne, E. coli, MRSA, STIs and anthrax that
should not be taken with milk, penicillins, and oral contraceptives
teratogenic effects, avoid if <8yrs (permanent discoloration)

, NSG 318 Final Exam
QUESTIONS AND CORRECT ANSWERS
(VERIFIED ANSWERS) PLUS RATIONALES
photosensitivity
fluconazole (Difulcan) - ANS✔✔-azole antifungal
used for candida infections and prophylactically for those undergoing bone marrow transplant.
drinks w caffeine are contraindicated when taking this drug.
gentamicin sulfate - ANS✔✔-antibiotic that is administered via IM or IV and used for
endocardiits, septicemia, bone/joint infection, and meningitis, NOT OM. may cause alopecia,
photosensitivity, tinnitus (especially with furosemide), nephrotoxic
invermectin (stromectol) - ANS✔✔-an anthelmic medication used to treat clients with parasitic
worms such as roundworm
injection site redness - ANS✔✔-expected side effect of isoniazid and ceftriaxone that the nurse
should monitor but does not require discontinuation of medication
levofloxacin (Levaquin) - ANS✔✔-antibiotic that interferes with enzyme DNA gyrase and is
used to treat cellulitis, impetigo and skin infections. may cause abdominal cramps, restlessness,
depression, photosensitivity, tinnitus and injection site reaction.
obtain specimen and cultures, increase fluids
metronidazide (Flagyl) - ANS✔✔-peptide medication that is used for anaerobic infections
including rosacea
oral contraceptives - ANS✔✔-may have reduced effects when taken with doxycycline
peak level - ANS✔✔-lab test that is drawn within 30-60 min after administration of a medication
to determine the amount of medication in the system
penicillin - ANS✔✔-broad spectrum antibiotic that inhibits bacterial cell wall synthesis and has
a beta-lactam ring structure
phlebitis - ANS✔✔-potential side effect of acyclovir that requires the nurse to assess IV site
prior to administration, throughout administration, and after
pyridoxine (Vitamin B6) - ANS✔✔-medication that may be required when taking an anti-TB
drug
sulfonamides - ANS✔✔-classification of antibiotic that inhibits bacterial synthesis of folic acid
what is the first thing the nurse should do when client is having an anaphylactic reaction to IV
antibiotics? - ANS✔✔-stop the infusion
superinfection - ANS✔✔-secondary infection caused when the normal flora is killed when
taking an antibiotic
TMP-SMX - ANS✔✔-two antibiotics that are combined that causes bacterial resistance to
develop more slowly than if one of the drugs were used alone
arthralgia, anemia
admin w water, do not take with antacids, avoid glipizide if allergic
thrush - ANS✔✔-oral candidiasis that is typically treated with the anti-fungal drug nystatin
tooth discoloration - ANS✔✔-side effect of doxycycline that can affect women in the last
trimester of pregnancy and children younger than 8 years old

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