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Berne
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LevyBerne
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8th Physiology
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8th Edition
& Stanton,
by Koeppen
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Berne and Levy Physiology 8th Edition KoeppenTest Bank
Koeppen: Berne and Levy Physiology, 8th Edition
Chapter 01: Principles of Cell
FunctionTest Bank
Multiple Choice
1. The subcellular structure that degrades proteins is called the:
A. Tight junction
B. Mitochondria
C. Lysosome
D. Plasma membrane
E. Ribosome
ANS: C
2. An experiment is done to measure the uptake of an amino acid into a cell. The following
data are obtained:
N
If Na+ is removed from the extracellular bathing solution, or if a drug is added that prevents the
cell from making adenosine triphosphate (ATP), the uptake of amino acid into the cell is
markedly reduced. According to this information, which of the followingmechanisms is
probably responsible for the transport of the amino acid into the cell?
A. Passive diffusion through the lipid bilayer
B. Uniporter
C. Transport ATPase
D. Na+ symporter
E. Na+ antiporter
ANS: D
3. A membrane permeable by only Na+ separates two compartments containing
Na2SO4,shown as follows:
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8th Edition by Koeppen & Stanton, Verified Chapters 1 - 44, Complete Newest Version.pdf
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Berne
BANK
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LevyBerne
Physiology
and Levy
8th Physiology
Edition by Koeppen
8th Edition
& Stanton,
by Koeppen
Verified
& Stanton,
Chapters
Verified
1 - 44,
Chapters
Complete
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Electrodes are placed in both compartments, and a voltage is applied (that of compartment A is
held at 0 mV). What voltage applied to compartment B would resultin no net movement of Na+
across the membrane separating the compartments?
A. –60 mV
B. –30 mV
C. 0 mV
D. +30 mV
E. +60 mV
ANS: E
4. The resting membrane potentN ce l lGis –B
ial oRfa I 85.C
mV. The intracellular and extracellular
U S N T
concentrations of several ions are indicated in the following table, as is the calculated
Nernst equilibrium potential (Ei) for each of these ions:
Ion Concentration Concentration Ei
Inside Cell Outside Cell
Na+ 12 mEq/L 145 mEq/L 66 mV
K+ 150 mEq/L 4 mEq/L –96 mV
Cl– 30 mEq/L 105 mEq/L –33 mV
Ca++ 0.0001 mmol/dL 1 mmol/dL 122 mV
The membrane has channels for Na+, K+, Cl–, and Ca++. The conductance of the
membrane is the greatest for which ion?
A. Na+
B. K+
C. Cl–
D. Ca++
ANS: B
5. A cell contains the following membrane transporters:
Na+ channelK+ channel
Na+,K+-ATPase
The resting membrane voltage of the cell is –80 mV, and the intracellular and
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8th Edition by Koeppen & Stanton, Verified Chapters 1 - 44, Complete Newest Version.pdf
,BANK For
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Berne
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and For
LevyBerne
Physiology
and Levy
8th Physiology
Edition by Koeppen
8th Edition
& Stanton,
by Koeppen
Verified
& Stanton,
Chapters
Verified
1 - 44,
Chapters
Complete
1 -Newest
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extracellular ion concentrations are as follows:
Ion Intracellular Extracellular
Concentration Concentration
Na+ 10 mEq/L 145 mEq/L
K+ 120 mEq/L 4 mEq/L
The cell is treated with a drug to inhibit the Na+,K+-ATPase. What would be the effect ofthis drug
on the following parameters?
Intracellular [Na+] Intracellular [K+] Cell Volume Membrane Voltage
A. Decrease Decrease Decrease Depolarize
B. Increase Decrease Increase Depolarize
C. Increase Increase Increase No change
D. Decrease Increase Decrease Hyperpolarize
E. Increase Increase Decrease Hyperpolarize
ANS: B
6. Which of the labeled proteins (shaded) is attached to the membrane by a
glycosylphosphatidylinositol (GPI) anchor?
ANS: E
7. A cell has channels for Na+, K+, and Cl– in its plasma membrane. The resting membrane
potential is –60 mV (cell interior negative). The intracellular and extracellular
concentrations for these ions, as well as the calculated Nernst potentials, are listed as
follows:
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8th Edition by Koeppen & Stanton, Verified Chapters 1 - 44, Complete Newest Version.pdf
,BANK For
TEST
Berne
BANK
and For
LevyBerne
Physiology
and Levy
8th Physiology
Edition by Koeppen
8th Edition
& Stanton,
by Koeppen
Verified
& Stanton,
Chapters
Verified
1 - 44,
Chapters
Complete
1 -Newest
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Ion Intracellular Extracellular Ei
Concentration Concentration
Na+ 14 mEq/L 140 mEq/L 60 mV
K+ 150 mEq/L 5 mEq/L –89 mV
Cl– 10 mEq/L 100 mEq/L –60 mV
A drug is applied to the cell that increases the permeability of the cell by Cl– (i.e., it opens Cl–
channels). What effect will this drug have on the net movement of Cl– acrossthe plasma
membrane?
A. Net Cl– movement out of the cell will be increased.
B. Net Cl– movement into the cell will be increased.
C. There will be no change in the net movement of Cl–.
ANS: C
8. Reducing the extracellular [K+] would be expected to have which of the following
effects on the resting membrane potential and on the excitability of ventricular
myocytes?
Membrane Potential Excitability
A. Unchanged Unchanged
B. Hyperpolarized GDT
ecBre.aC
seO
d
C. Hyperpolarized Increased
D. Depolarized Decreased
E. Depolarized Increased
ANS: B
9. A cell is bathed in an isotonic NaCl solution that contains 5 mmol/L of glucose. The
intracellular concentration of glucose is 10 mmol/L. What is the most likely mechanism
for the transport of glucose across the plasma membrane into this cell?
A. Glucose uniporter
B. Na+-glucose symporter
C. Na+-glucose antiporter
D. Diffusion of glucose through the lipid bilayer of the membrane
ANS: B
10. A blood sample is taken from an individual whose blood osmolality is 295 mOsm per
kilogram of water. Red blood cells from this sample are then placed in the following
solutions:
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8th Edition by Koeppen & Stanton, Verified Chapters 1 - 44, Complete Newest Version.pdf
TEST
Berne
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and For
LevyBerne
Physiology
and Levy
8th Physiology
Edition by Koeppen
8th Edition
& Stanton,
by Koeppen
Verified
& Stanton,
Chapters
Verified
1 - 44,
Chapters
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1 -Newest
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Berne and Levy Physiology 8th Edition KoeppenTest Bank
Koeppen: Berne and Levy Physiology, 8th Edition
Chapter 01: Principles of Cell
FunctionTest Bank
Multiple Choice
1. The subcellular structure that degrades proteins is called the:
A. Tight junction
B. Mitochondria
C. Lysosome
D. Plasma membrane
E. Ribosome
ANS: C
2. An experiment is done to measure the uptake of an amino acid into a cell. The following
data are obtained:
N
If Na+ is removed from the extracellular bathing solution, or if a drug is added that prevents the
cell from making adenosine triphosphate (ATP), the uptake of amino acid into the cell is
markedly reduced. According to this information, which of the followingmechanisms is
probably responsible for the transport of the amino acid into the cell?
A. Passive diffusion through the lipid bilayer
B. Uniporter
C. Transport ATPase
D. Na+ symporter
E. Na+ antiporter
ANS: D
3. A membrane permeable by only Na+ separates two compartments containing
Na2SO4,shown as follows:
https://www.stuvia.com/user/parkrobertson99
TEST BANK For Berne and Levy Physiology
https://www.stuvia.com/user/parkrobertson99
8th Edition by Koeppen & Stanton, Verified Chapters 1 - 44, Complete Newest Version.pdf
,BANK For
TEST
Berne
BANK
and For
LevyBerne
Physiology
and Levy
8th Physiology
Edition by Koeppen
8th Edition
& Stanton,
by Koeppen
Verified
& Stanton,
Chapters
Verified
1 - 44,
Chapters
Complete
1 -Newest
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Complete
Version.pdfhttps://www.stuvia.com/user/parkrobert
Newest Version.pdfhttps://www.stuvia.com/u
Electrodes are placed in both compartments, and a voltage is applied (that of compartment A is
held at 0 mV). What voltage applied to compartment B would resultin no net movement of Na+
across the membrane separating the compartments?
A. –60 mV
B. –30 mV
C. 0 mV
D. +30 mV
E. +60 mV
ANS: E
4. The resting membrane potentN ce l lGis –B
ial oRfa I 85.C
mV. The intracellular and extracellular
U S N T
concentrations of several ions are indicated in the following table, as is the calculated
Nernst equilibrium potential (Ei) for each of these ions:
Ion Concentration Concentration Ei
Inside Cell Outside Cell
Na+ 12 mEq/L 145 mEq/L 66 mV
K+ 150 mEq/L 4 mEq/L –96 mV
Cl– 30 mEq/L 105 mEq/L –33 mV
Ca++ 0.0001 mmol/dL 1 mmol/dL 122 mV
The membrane has channels for Na+, K+, Cl–, and Ca++. The conductance of the
membrane is the greatest for which ion?
A. Na+
B. K+
C. Cl–
D. Ca++
ANS: B
5. A cell contains the following membrane transporters:
Na+ channelK+ channel
Na+,K+-ATPase
The resting membrane voltage of the cell is –80 mV, and the intracellular and
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8th Edition by Koeppen & Stanton, Verified Chapters 1 - 44, Complete Newest Version.pdf
,BANK For
TEST
Berne
BANK
and For
LevyBerne
Physiology
and Levy
8th Physiology
Edition by Koeppen
8th Edition
& Stanton,
by Koeppen
Verified
& Stanton,
Chapters
Verified
1 - 44,
Chapters
Complete
1 -Newest
44, https://www.stuvia.com/user/parkrobertson99
Complete
Version.pdfhttps://www.stuvia.com/user/parkrobert
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extracellular ion concentrations are as follows:
Ion Intracellular Extracellular
Concentration Concentration
Na+ 10 mEq/L 145 mEq/L
K+ 120 mEq/L 4 mEq/L
The cell is treated with a drug to inhibit the Na+,K+-ATPase. What would be the effect ofthis drug
on the following parameters?
Intracellular [Na+] Intracellular [K+] Cell Volume Membrane Voltage
A. Decrease Decrease Decrease Depolarize
B. Increase Decrease Increase Depolarize
C. Increase Increase Increase No change
D. Decrease Increase Decrease Hyperpolarize
E. Increase Increase Decrease Hyperpolarize
ANS: B
6. Which of the labeled proteins (shaded) is attached to the membrane by a
glycosylphosphatidylinositol (GPI) anchor?
ANS: E
7. A cell has channels for Na+, K+, and Cl– in its plasma membrane. The resting membrane
potential is –60 mV (cell interior negative). The intracellular and extracellular
concentrations for these ions, as well as the calculated Nernst potentials, are listed as
follows:
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TEST BANK For Berne and Levy Physiology
https://www.stuvia.com/user/parkrobertson99
8th Edition by Koeppen & Stanton, Verified Chapters 1 - 44, Complete Newest Version.pdf
,BANK For
TEST
Berne
BANK
and For
LevyBerne
Physiology
and Levy
8th Physiology
Edition by Koeppen
8th Edition
& Stanton,
by Koeppen
Verified
& Stanton,
Chapters
Verified
1 - 44,
Chapters
Complete
1 -Newest
44, https://www.stuvia.com/user/parkrobertson99
Complete
Version.pdfhttps://www.stuvia.com/user/parkrobert
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Ion Intracellular Extracellular Ei
Concentration Concentration
Na+ 14 mEq/L 140 mEq/L 60 mV
K+ 150 mEq/L 5 mEq/L –89 mV
Cl– 10 mEq/L 100 mEq/L –60 mV
A drug is applied to the cell that increases the permeability of the cell by Cl– (i.e., it opens Cl–
channels). What effect will this drug have on the net movement of Cl– acrossthe plasma
membrane?
A. Net Cl– movement out of the cell will be increased.
B. Net Cl– movement into the cell will be increased.
C. There will be no change in the net movement of Cl–.
ANS: C
8. Reducing the extracellular [K+] would be expected to have which of the following
effects on the resting membrane potential and on the excitability of ventricular
myocytes?
Membrane Potential Excitability
A. Unchanged Unchanged
B. Hyperpolarized GDT
ecBre.aC
seO
d
C. Hyperpolarized Increased
D. Depolarized Decreased
E. Depolarized Increased
ANS: B
9. A cell is bathed in an isotonic NaCl solution that contains 5 mmol/L of glucose. The
intracellular concentration of glucose is 10 mmol/L. What is the most likely mechanism
for the transport of glucose across the plasma membrane into this cell?
A. Glucose uniporter
B. Na+-glucose symporter
C. Na+-glucose antiporter
D. Diffusion of glucose through the lipid bilayer of the membrane
ANS: B
10. A blood sample is taken from an individual whose blood osmolality is 295 mOsm per
kilogram of water. Red blood cells from this sample are then placed in the following
solutions:
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