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  • Advanced Pathophysiology
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Advanced Pathophysiology Mid-Term Study Guide Exam

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2026/2027 Written for academic year
Institution Advanced Pathophysiology
Course Advanced pathophysiology
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1) What causes the rapid change in the resting membrane potential to initiate an action potential? - Correct answer Na+ gates open, and Na+ rushes into the cell, changing the membrane potential from - to + 2) What is a consequence of leakage of lysosome enzymes during chemical injury? - Correct answer enzymatic digestion of the nucleus and nucleolus occurs, halting DNA synthesis 3) In hypoxic injury, sodium enters the cell and causes swelling because: - Correct answer ATP is insufficient to maintain the pump that keeps Na+ out of the cell. 4) What mechanisms occur in the liver cells as a result of lipid accumulation? - Correct answer Increased synthesis of triglycerides from fatty acids and decreased synthesis of Apo proteins 5) What is the effect of oxidized low-density lipoproteins (LDLs) in atherosclerosis? - Correct answer LDLs cause smooth muscle proliferation

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