ATI PN GENETICS AND GENOMICS IN MATERNAL
NEWBORN CARE ASSESSMENT COMPREHENSIVE
PRACTICE EXAM LATEST UPDATED ACTUAL FINAL
EXAM WITH ALL POSSIBLE AND MOST TESTED 100
PRACTICE QUESTIONS AND 100% CORRECT VERIFIED
ANSWERS FULLY SOLVED WITH DETAILED
RATIONALES PLUS EXPERT ANSWER KEY 2026-2027
FINAL EXAM UPDATED VERSION 100% GUARANTEED
PASS MOST RECENT!!!
1. A nurse is educating a pregnant client about
genetic testing. Which statement by the client
indicates a need for further teaching?
A. “Genetic testing can identify some chromosomal
abnormalities.”
B. “Genetic testing is 100% accurate for all
conditions.”
C. “Results may take several weeks to return.”
D. “Testing is optional and requires my consent.”
Correct Answer: B. “Genetic testing is 100%
accurate for all conditions.”
,Rationale: No genetic test is 100% accurate; false
positives and negatives occur. The other
statements are accurate regarding testing
limitations, timeframes, and consent.
2. A newborn is noted to have a single palmar
crease, low-set ears, and hypotonia. Which
chromosomal condition is most likely?
A. Turner syndrome
B. Klinefelter syndrome
C. Down syndrome (trisomy 21)
D. Edwards syndrome (trisomy 18)
Correct Answer: C. Down syndrome (trisomy 21)
Rationale: Single palmar crease, low-set ears, and
hypotonia are classic features of Down syndrome.
Turner and Klinefelter involve sex chromosomes;
Edwards has severe growth restriction and rocker-
bottom feet.
3. A pregnant client at 16 week gestation has a
positive quad screen for neural tube defects. Which
follow-up test is most appropriate?
A. Amniocentesis
,B. Chorionic villus sampling (CVS)
C. Ultrasound for fetal anatomy
D. Nonstress test
Correct Answer: C. Ultrasound for fetal anatomy
Rationale: A positive quad screen for neural tube
defects (elevated AFP) is best followed by a
detailed ultrasound to assess the fetal spine and
skull. Amniocentesis for AFP in amniotic fluid may
be done later, but ultrasound is the initial step. CVS
is for first-trimester and does not assess NTDs.
4. Which genetic condition is associated with a
deletion on chromosome 22q11.2?
A. Cystic fibrosis
B. DiGeorge syndrome (velocardiofacial syndrome)
C. Fragile X syndrome
D. Phenylketonuria
Correct Answer: B. DiGeorge syndrome
(velocardiofacial syndrome)
Rationale: DiGeorge syndrome is caused by a
microdeletion on chromosome 22q11.2, leading to
cardiac defects, cleft palate, and immune
, deficiency. CF is on chromosome 7, Fragile X is a
trinucleotide repeat, PKU is a metabolic disorder.
5. A mother with a family history of hemophilia A
asks about her male fetus’s risk. Hemophilia A is X-
linked recessive. If the mother is a carrier and the
father is unaffected, what is the risk for a male
fetus?
A. 0%
B. 25%
C. 50%
D. 100%
Correct Answer: C. 50%
Rationale: Each male fetus has a 50% chance of
inheriting the affected X chromosome from the
carrier mother. Females have a 50% chance of
being carriers.
6. A newborn screening test reveals elevated
phenylalanine levels. Which dietary intervention is
critical?
A. High-protein formula
B. Low-phenylalanine formula
NEWBORN CARE ASSESSMENT COMPREHENSIVE
PRACTICE EXAM LATEST UPDATED ACTUAL FINAL
EXAM WITH ALL POSSIBLE AND MOST TESTED 100
PRACTICE QUESTIONS AND 100% CORRECT VERIFIED
ANSWERS FULLY SOLVED WITH DETAILED
RATIONALES PLUS EXPERT ANSWER KEY 2026-2027
FINAL EXAM UPDATED VERSION 100% GUARANTEED
PASS MOST RECENT!!!
1. A nurse is educating a pregnant client about
genetic testing. Which statement by the client
indicates a need for further teaching?
A. “Genetic testing can identify some chromosomal
abnormalities.”
B. “Genetic testing is 100% accurate for all
conditions.”
C. “Results may take several weeks to return.”
D. “Testing is optional and requires my consent.”
Correct Answer: B. “Genetic testing is 100%
accurate for all conditions.”
,Rationale: No genetic test is 100% accurate; false
positives and negatives occur. The other
statements are accurate regarding testing
limitations, timeframes, and consent.
2. A newborn is noted to have a single palmar
crease, low-set ears, and hypotonia. Which
chromosomal condition is most likely?
A. Turner syndrome
B. Klinefelter syndrome
C. Down syndrome (trisomy 21)
D. Edwards syndrome (trisomy 18)
Correct Answer: C. Down syndrome (trisomy 21)
Rationale: Single palmar crease, low-set ears, and
hypotonia are classic features of Down syndrome.
Turner and Klinefelter involve sex chromosomes;
Edwards has severe growth restriction and rocker-
bottom feet.
3. A pregnant client at 16 week gestation has a
positive quad screen for neural tube defects. Which
follow-up test is most appropriate?
A. Amniocentesis
,B. Chorionic villus sampling (CVS)
C. Ultrasound for fetal anatomy
D. Nonstress test
Correct Answer: C. Ultrasound for fetal anatomy
Rationale: A positive quad screen for neural tube
defects (elevated AFP) is best followed by a
detailed ultrasound to assess the fetal spine and
skull. Amniocentesis for AFP in amniotic fluid may
be done later, but ultrasound is the initial step. CVS
is for first-trimester and does not assess NTDs.
4. Which genetic condition is associated with a
deletion on chromosome 22q11.2?
A. Cystic fibrosis
B. DiGeorge syndrome (velocardiofacial syndrome)
C. Fragile X syndrome
D. Phenylketonuria
Correct Answer: B. DiGeorge syndrome
(velocardiofacial syndrome)
Rationale: DiGeorge syndrome is caused by a
microdeletion on chromosome 22q11.2, leading to
cardiac defects, cleft palate, and immune
, deficiency. CF is on chromosome 7, Fragile X is a
trinucleotide repeat, PKU is a metabolic disorder.
5. A mother with a family history of hemophilia A
asks about her male fetus’s risk. Hemophilia A is X-
linked recessive. If the mother is a carrier and the
father is unaffected, what is the risk for a male
fetus?
A. 0%
B. 25%
C. 50%
D. 100%
Correct Answer: C. 50%
Rationale: Each male fetus has a 50% chance of
inheriting the affected X chromosome from the
carrier mother. Females have a 50% chance of
being carriers.
6. A newborn screening test reveals elevated
phenylalanine levels. Which dietary intervention is
critical?
A. High-protein formula
B. Low-phenylalanine formula
