NGR 6172 Questions with 100% Verified Answers Latest
Update
Question: The primary care nurse practitioner (NP) writes a prescription for an antibiotic
using an electronic drug prescription system. The pharmacist will fill this prescription when:
A - The electronic prescription is received. B - The patient brings a written copy of the
prescription C - A copy of the written prescription is faxed to the pharmacy D - The
pharmacist accesses the patient's electronic record to verify
Answer:
A - The electronic prescription is received
Question: Which of the following are common components found on a prescription for a
Controlled Substance? Select all that apply. Full Name of Drug Strength or Concentration
DEA Number Directions for use
Answer:
All are correct
Question: For each term, please provide the correct description. Please note you will only
receive credit if all terms are correctly matched with their respective description.
Answer:
Absorption - The transportation of a medication from the administration site to the
bloodstream Metabolism - The biotransformation of medications so that they can be
excreted from the body f value - The fraction of the frug that reaches the systematic
circulation Distribution - The transport of a drug in body fluids from the bloodstream to
various tissues in the body
Question: A primary care nurse practitioner (NP) prescribes a drug to an 80-year-old
African-American woman. When selecting a drug and determining the correct dose, the NP
should understand that the knowledge of how age, race, and gender may affect drug
excretion is based on an understanding of: A - Bioavailability B - Pharmacokinetics C -
Pharmacodynamics D - Anatomy and physiology
Answer:
B - Pharmacokinetics
Question: The primary care NP should understand that a drug is at a therapeutic level when
it is: A - At peak plasma level B - Past 4 or 5 half-lives C - At its steady plasma state D -
Between minimal effective concentration and toxic levels
Answer:
D - Between minimal effective concentration and toxic levels
Question: A primary care NP wishes to order a drug that will be effective immediately after
,administration of the drug. Which route should the NP choose? A- Rectal B - Topical C -
Sublingual D - Intramuscular
Answer:
C - sublingual
Question: When considering an inhaled corticosteroid to treat asthma in an adult, the
patient asks you, as the primary care provider, why the corticosteroid is given by inhalation
instead of oral administration. What is your best response? A - Inhaled corticosteroids work
slowly, and the action is more sustained B - Inhaled corticosteroids have a few systemic side
effects C - Inhaled corticosteroids can use the local blood vessels to deliver the medication
dose D - Inhaled corticosteroid doses are more easily regulated
Answer:
B - Inhaled corticosteroids have a few systemic side effects
Question: A primary care NP is prescribing a drug for a patient who does not take any other
medications. The NP should realize that: A - CYP450 enzyme reactions will not interfere with
this drug's metabolism B - Substrates such as alcohol cannot interfere with the drug when
the patient is abstaining C - Food-drug interactions are limited to those where food
enhances or inhibits drug absorption D - A thorough history of diet, alcohol use, smoking,
and OTC and herbal products is required
Answer:
D - A thorough history of diet, alcohol use, smoking, and OTC and herbal products is
required
Question: Pharmacogenomics is the science of DNA analysis for the purpose of identifying
gene variations that impact medication response. True False
Answer:
True
Question: When considering the application of pharmacokinetics and pharmacodynamics,
which of the following practical suggestions can be made for rational drug therapy? Select
all that apply. A - Use as few medications as possible B - Use the highest effective dose C -
Start low and go slow D - Use a medication only when clearly indicated for a specific
purpose
Answer:
A - Use as few medications as possible C - Start low and go slow D - Use a medication only
when clearly indicated for a specific purpose
Question: A pharmacokinetic study of a new antihypertensive drug is being conducted in
healthy human volunteers. The half-life of the drug after administration by continuous
intravenous infusion is 12 hours. Which of the following best approximates the time for the
drug to reach steady state? A - 60 hours B - 24 hours C - 36 hours D - 120 hours
, Answer:
A - 60 hours
Question: You are explaining the meaning of pharmacokinetics to an advanced practice
student. Which of the following statements is correct? A - Pharmacokinetics is the
biochemical and physiologic action medications on the body B - Pharmacokinetics refers to
the processes of absorption, distribution, metabolism, and elimination of medication C -
Pharmacokinetics is the peak and trough levels when medication reaches a steady state D -
Pharmacokinetics refers to the transportation of a medication from the administration site
to the bloodstream
Answer:
B - Pharmacokinetics refers to the processes of absorption, distribution, metabolism, and
elimination of medication
Question: When prescribing oral medications, the primary care provider understands that
these medications are subject to first-pass effect. What are the consequences of first-pass
effect of oral medications? A -Oral medications are excreted more slowly. B - Oral
medications become less bioavailable. C - Oral medications have increased absorption. D -
Oral medications enter the circulation more quickly.
Answer:
B - Oral medications become less bioavailable
Question: Clopidogrel is a produg that requires functional CYP2C19 enzyme activity to be
activated and exert its pharmacological effect. True False
Answer:
True
Question: An adult patient is taking a prescribed oral medication that causes gastric reflux.
The patient asks you why you have cautioned against taking antacids with this medication.
What is your best response? A - Taking an antacid may block elimination of this medication.
B - Taking an antacid may alter the distribution of this medication. C - Taking an antacid
may lead to increased drug toxicity. D - Taking an antacid may interfere with the absorption
of medication.
Answer:
D - Taking an antacid may interfere with the absorption of medication
Question: Which of the following statements is correct regarding warfarin
pharmacogenetics? A - Reduced CYP2C9 enzyme activity is associated with increased
warfarin sensitivity and may result in requiring lower doses. B - Reduced CYP2C9 enzyme
activity is associated with decreased warfarin sensitivity and may result in requiring higher
doses C - It is appropriate to use a pharmacogenetic guided warfarin dosing for an African
American who had CYP2C9 testing by a lab that only detected 2 and 3 alleles. D - The
CYP2C9 5, 6, 8, and 11 alleles are highly frequent among all ethnic groups
, Answer:
A - Reduced CYP2C9 enzyme activity is associated with increased warfarin sensitivity and
may result in requiring lower doses
Question: A primary care patient asks you to explain the role of pharmacogenomics in
prescribing medications. What explanation concerning pharmacogenomics is not correct? A
- Pharmacogenomics refers to the treatment of genetic alterations using gene therapy. B -
Pharmacogenomics identifies gene variations that impact medication response. C -
Pharmacogenomics considers that responses to medications result from individual and
genetic differences. D - Pharmacogenomics refers to genetic polymorphisms found in
specific patient populations.
Answer:
A - Pharmacogenomics refers to the treatment of genetic alterations using gene therapy
Question: You are preparing to administer an IV medication to a patient in your care. In
considering that the pharmacokinetic properties of medication are affected by the route of
administration, which of the following is true about the IV route? A - For IV medications,
absorption occurs over time followed by distribution and elimination. B - For IV medications,
only distribution and elimination occur. C - For IV medications, first-pass metabolism occurs
followed by absorption. D - For IV medications, variable bioavailability affects elimination.
Answer:
B - For IV medications, only distribution and elimination occur
Question: As the primary care provider, you are preparing to prescribe a medication that
you know has nonlinear kinetics. What action should you plan to take in the care of this
patient? A - Monitor the patient's creatinine clearance at baseline and periodically. B -
Administer a higher loading dose followed by the maintenance dose. C - Frequently monitor
the patient for desired and adverse effects. D - Administer the medication sublingually to
avoid the first-pass effect.
Answer:
C - Frequently monitor the patient for desired and adverse effects
Question: A patient for whom you have prescribed medications has taken a
direct-to-consumer genetic test that indicates one of the prescribed medications may not be
effective based on the test results received. What is your best response to this patient's
concern? A - "You can stop taking this medication, and we can substitute another drug for
this one." B - "Many genetic tests make claims about the effects of specific medications that
are not supported by scientific evidence." C - "Consumer genetic tests have a high degree
of accuracy, but we will wait before we take any action." D - "The test results indicate that
you may need a higher-than-normal dose to obtain the desired effect."
Answer:
B - "Many genetic tests make claims about the effects of specific medications that are not
Update
Question: The primary care nurse practitioner (NP) writes a prescription for an antibiotic
using an electronic drug prescription system. The pharmacist will fill this prescription when:
A - The electronic prescription is received. B - The patient brings a written copy of the
prescription C - A copy of the written prescription is faxed to the pharmacy D - The
pharmacist accesses the patient's electronic record to verify
Answer:
A - The electronic prescription is received
Question: Which of the following are common components found on a prescription for a
Controlled Substance? Select all that apply. Full Name of Drug Strength or Concentration
DEA Number Directions for use
Answer:
All are correct
Question: For each term, please provide the correct description. Please note you will only
receive credit if all terms are correctly matched with their respective description.
Answer:
Absorption - The transportation of a medication from the administration site to the
bloodstream Metabolism - The biotransformation of medications so that they can be
excreted from the body f value - The fraction of the frug that reaches the systematic
circulation Distribution - The transport of a drug in body fluids from the bloodstream to
various tissues in the body
Question: A primary care nurse practitioner (NP) prescribes a drug to an 80-year-old
African-American woman. When selecting a drug and determining the correct dose, the NP
should understand that the knowledge of how age, race, and gender may affect drug
excretion is based on an understanding of: A - Bioavailability B - Pharmacokinetics C -
Pharmacodynamics D - Anatomy and physiology
Answer:
B - Pharmacokinetics
Question: The primary care NP should understand that a drug is at a therapeutic level when
it is: A - At peak plasma level B - Past 4 or 5 half-lives C - At its steady plasma state D -
Between minimal effective concentration and toxic levels
Answer:
D - Between minimal effective concentration and toxic levels
Question: A primary care NP wishes to order a drug that will be effective immediately after
,administration of the drug. Which route should the NP choose? A- Rectal B - Topical C -
Sublingual D - Intramuscular
Answer:
C - sublingual
Question: When considering an inhaled corticosteroid to treat asthma in an adult, the
patient asks you, as the primary care provider, why the corticosteroid is given by inhalation
instead of oral administration. What is your best response? A - Inhaled corticosteroids work
slowly, and the action is more sustained B - Inhaled corticosteroids have a few systemic side
effects C - Inhaled corticosteroids can use the local blood vessels to deliver the medication
dose D - Inhaled corticosteroid doses are more easily regulated
Answer:
B - Inhaled corticosteroids have a few systemic side effects
Question: A primary care NP is prescribing a drug for a patient who does not take any other
medications. The NP should realize that: A - CYP450 enzyme reactions will not interfere with
this drug's metabolism B - Substrates such as alcohol cannot interfere with the drug when
the patient is abstaining C - Food-drug interactions are limited to those where food
enhances or inhibits drug absorption D - A thorough history of diet, alcohol use, smoking,
and OTC and herbal products is required
Answer:
D - A thorough history of diet, alcohol use, smoking, and OTC and herbal products is
required
Question: Pharmacogenomics is the science of DNA analysis for the purpose of identifying
gene variations that impact medication response. True False
Answer:
True
Question: When considering the application of pharmacokinetics and pharmacodynamics,
which of the following practical suggestions can be made for rational drug therapy? Select
all that apply. A - Use as few medications as possible B - Use the highest effective dose C -
Start low and go slow D - Use a medication only when clearly indicated for a specific
purpose
Answer:
A - Use as few medications as possible C - Start low and go slow D - Use a medication only
when clearly indicated for a specific purpose
Question: A pharmacokinetic study of a new antihypertensive drug is being conducted in
healthy human volunteers. The half-life of the drug after administration by continuous
intravenous infusion is 12 hours. Which of the following best approximates the time for the
drug to reach steady state? A - 60 hours B - 24 hours C - 36 hours D - 120 hours
, Answer:
A - 60 hours
Question: You are explaining the meaning of pharmacokinetics to an advanced practice
student. Which of the following statements is correct? A - Pharmacokinetics is the
biochemical and physiologic action medications on the body B - Pharmacokinetics refers to
the processes of absorption, distribution, metabolism, and elimination of medication C -
Pharmacokinetics is the peak and trough levels when medication reaches a steady state D -
Pharmacokinetics refers to the transportation of a medication from the administration site
to the bloodstream
Answer:
B - Pharmacokinetics refers to the processes of absorption, distribution, metabolism, and
elimination of medication
Question: When prescribing oral medications, the primary care provider understands that
these medications are subject to first-pass effect. What are the consequences of first-pass
effect of oral medications? A -Oral medications are excreted more slowly. B - Oral
medications become less bioavailable. C - Oral medications have increased absorption. D -
Oral medications enter the circulation more quickly.
Answer:
B - Oral medications become less bioavailable
Question: Clopidogrel is a produg that requires functional CYP2C19 enzyme activity to be
activated and exert its pharmacological effect. True False
Answer:
True
Question: An adult patient is taking a prescribed oral medication that causes gastric reflux.
The patient asks you why you have cautioned against taking antacids with this medication.
What is your best response? A - Taking an antacid may block elimination of this medication.
B - Taking an antacid may alter the distribution of this medication. C - Taking an antacid
may lead to increased drug toxicity. D - Taking an antacid may interfere with the absorption
of medication.
Answer:
D - Taking an antacid may interfere with the absorption of medication
Question: Which of the following statements is correct regarding warfarin
pharmacogenetics? A - Reduced CYP2C9 enzyme activity is associated with increased
warfarin sensitivity and may result in requiring lower doses. B - Reduced CYP2C9 enzyme
activity is associated with decreased warfarin sensitivity and may result in requiring higher
doses C - It is appropriate to use a pharmacogenetic guided warfarin dosing for an African
American who had CYP2C9 testing by a lab that only detected 2 and 3 alleles. D - The
CYP2C9 5, 6, 8, and 11 alleles are highly frequent among all ethnic groups
, Answer:
A - Reduced CYP2C9 enzyme activity is associated with increased warfarin sensitivity and
may result in requiring lower doses
Question: A primary care patient asks you to explain the role of pharmacogenomics in
prescribing medications. What explanation concerning pharmacogenomics is not correct? A
- Pharmacogenomics refers to the treatment of genetic alterations using gene therapy. B -
Pharmacogenomics identifies gene variations that impact medication response. C -
Pharmacogenomics considers that responses to medications result from individual and
genetic differences. D - Pharmacogenomics refers to genetic polymorphisms found in
specific patient populations.
Answer:
A - Pharmacogenomics refers to the treatment of genetic alterations using gene therapy
Question: You are preparing to administer an IV medication to a patient in your care. In
considering that the pharmacokinetic properties of medication are affected by the route of
administration, which of the following is true about the IV route? A - For IV medications,
absorption occurs over time followed by distribution and elimination. B - For IV medications,
only distribution and elimination occur. C - For IV medications, first-pass metabolism occurs
followed by absorption. D - For IV medications, variable bioavailability affects elimination.
Answer:
B - For IV medications, only distribution and elimination occur
Question: As the primary care provider, you are preparing to prescribe a medication that
you know has nonlinear kinetics. What action should you plan to take in the care of this
patient? A - Monitor the patient's creatinine clearance at baseline and periodically. B -
Administer a higher loading dose followed by the maintenance dose. C - Frequently monitor
the patient for desired and adverse effects. D - Administer the medication sublingually to
avoid the first-pass effect.
Answer:
C - Frequently monitor the patient for desired and adverse effects
Question: A patient for whom you have prescribed medications has taken a
direct-to-consumer genetic test that indicates one of the prescribed medications may not be
effective based on the test results received. What is your best response to this patient's
concern? A - "You can stop taking this medication, and we can substitute another drug for
this one." B - "Many genetic tests make claims about the effects of specific medications that
are not supported by scientific evidence." C - "Consumer genetic tests have a high degree
of accuracy, but we will wait before we take any action." D - "The test results indicate that
you may need a higher-than-normal dose to obtain the desired effect."
Answer:
B - "Many genetic tests make claims about the effects of specific medications that are not
