PRITE 2025/2026 High Yield Practice Questions (Set
of 100) WITH CORRECT ANSWERS
Clinical Neurosciences & Neurology
1. A 60yearold righthanded man presents with difficulty finding his way
around familiar places. On examination, he only writes on the right half of the
paper when asked to draw a clock. Where is the most likely location of the
lesion?
A) Left parietal lobe
B) Right parietal lobe
C) Left frontal lobe
D) Right temporal lobe
E) Occipital lobe
Correct Answer: B) Right parietal lobe
Rationale: Leftsided hemineglect (only writing on the right half of the paper)
is classically associated with lesions of the contralateral (right) parietal lobe,
particularly the inferior parietal lobule.
,2. A 66yearold with hypertension develops acute vertigo, diplopia, nausea,
vomiting, hiccups, left facial numbness, nystagmus, hoarseness, ataxia of the
limbs, staggering gait, and a tendency to fall to the left. What is the most likely
diagnosis?
A) Cerebellar stroke
B) Lateral medullary (Wallenberg) syndrome
C) Midbrain stroke
D) Pontine stroke
E) Vertebral artery dissection
Correct Answer: B) Lateral medullary (Wallenberg) syndrome
Rationale: Lateral medullary syndrome (Wallenberg syndrome) is caused by
occlusion of the posterior inferior cerebellar artery (PICA) or vertebral artery.
Classic features include vertigo, nystagmus, nausea, vomiting, dysphagia,
hoarseness, ipsilateral facial numbness, contralateral body numbness, ataxia,
and Horner syndrome.
3. Repetitive transcranial magnetic stimulation (rTMS) for the treatment of
unipolar depression targets which brain region?
A) Ventral striatum
B) Locus coeruleus
C) Periamygdaloid cortex
D) Medial temporal cortex
E) Dorsolateral prefrontal cortex
,Correct Answer: E) Dorsolateral prefrontal cortex
Rationale: rTMS for depression targets the left dorsolateral prefrontal cortex
(DLPFC), which is thought to be hypoactive in depressive states. Stimulation
of this region modulates neural circuits involved in mood regulation.
4. The uncinate fasciculus connects which of the following brain regions?
A) Frontal and parietal lobes
B) Temporal and orbitofrontal cortices
C) Occipital and temporal lobes
D) Wernicke's area and Broca's area
E) Cingulate gyrus and subcortical nuclei
Correct Answer: B) Temporal and orbitofrontal cortices
Rationale: The uncinate fasciculus is a white matter tract that connects the
anterior temporal lobe (including the amygdala) with the orbitofrontal cortex.
It is involved in memory, emotional processing, and social cognition.
5. The arcuate fasciculus connects which of the following?
A) Frontal and parietal lobes
B) Temporal and orbitofrontal cortices
, C) Wernicke's area and Broca's area
D) Occipital and temporal lobes
E) Cingulate gyrus and subcortical nuclei
Correct Answer: C) Wernicke's area and Broca's area
Rationale: The arcuate fasciculus is a bundle of fibers that connects
Wernicke's area (temporal lobe, language comprehension) with Broca's area
(frontal lobe, language production). Damage to this tract can result in
conduction aphasia.
6. The primary taste cortex in humans is located in which cortical area?
A) Dorsolateral prefrontal cortex
B) Orbitofrontal cortex
C) Anterior insular cortex
D) Somatosensory cortex
E) Posterior temporal cortex
Correct Answer: C) Anterior insular cortex
Rationale: The primary gustatory (taste) cortex is located in the anterior
insula and the adjacent frontal operculum.
of 100) WITH CORRECT ANSWERS
Clinical Neurosciences & Neurology
1. A 60yearold righthanded man presents with difficulty finding his way
around familiar places. On examination, he only writes on the right half of the
paper when asked to draw a clock. Where is the most likely location of the
lesion?
A) Left parietal lobe
B) Right parietal lobe
C) Left frontal lobe
D) Right temporal lobe
E) Occipital lobe
Correct Answer: B) Right parietal lobe
Rationale: Leftsided hemineglect (only writing on the right half of the paper)
is classically associated with lesions of the contralateral (right) parietal lobe,
particularly the inferior parietal lobule.
,2. A 66yearold with hypertension develops acute vertigo, diplopia, nausea,
vomiting, hiccups, left facial numbness, nystagmus, hoarseness, ataxia of the
limbs, staggering gait, and a tendency to fall to the left. What is the most likely
diagnosis?
A) Cerebellar stroke
B) Lateral medullary (Wallenberg) syndrome
C) Midbrain stroke
D) Pontine stroke
E) Vertebral artery dissection
Correct Answer: B) Lateral medullary (Wallenberg) syndrome
Rationale: Lateral medullary syndrome (Wallenberg syndrome) is caused by
occlusion of the posterior inferior cerebellar artery (PICA) or vertebral artery.
Classic features include vertigo, nystagmus, nausea, vomiting, dysphagia,
hoarseness, ipsilateral facial numbness, contralateral body numbness, ataxia,
and Horner syndrome.
3. Repetitive transcranial magnetic stimulation (rTMS) for the treatment of
unipolar depression targets which brain region?
A) Ventral striatum
B) Locus coeruleus
C) Periamygdaloid cortex
D) Medial temporal cortex
E) Dorsolateral prefrontal cortex
,Correct Answer: E) Dorsolateral prefrontal cortex
Rationale: rTMS for depression targets the left dorsolateral prefrontal cortex
(DLPFC), which is thought to be hypoactive in depressive states. Stimulation
of this region modulates neural circuits involved in mood regulation.
4. The uncinate fasciculus connects which of the following brain regions?
A) Frontal and parietal lobes
B) Temporal and orbitofrontal cortices
C) Occipital and temporal lobes
D) Wernicke's area and Broca's area
E) Cingulate gyrus and subcortical nuclei
Correct Answer: B) Temporal and orbitofrontal cortices
Rationale: The uncinate fasciculus is a white matter tract that connects the
anterior temporal lobe (including the amygdala) with the orbitofrontal cortex.
It is involved in memory, emotional processing, and social cognition.
5. The arcuate fasciculus connects which of the following?
A) Frontal and parietal lobes
B) Temporal and orbitofrontal cortices
, C) Wernicke's area and Broca's area
D) Occipital and temporal lobes
E) Cingulate gyrus and subcortical nuclei
Correct Answer: C) Wernicke's area and Broca's area
Rationale: The arcuate fasciculus is a bundle of fibers that connects
Wernicke's area (temporal lobe, language comprehension) with Broca's area
(frontal lobe, language production). Damage to this tract can result in
conduction aphasia.
6. The primary taste cortex in humans is located in which cortical area?
A) Dorsolateral prefrontal cortex
B) Orbitofrontal cortex
C) Anterior insular cortex
D) Somatosensory cortex
E) Posterior temporal cortex
Correct Answer: C) Anterior insular cortex
Rationale: The primary gustatory (taste) cortex is located in the anterior
insula and the adjacent frontal operculum.
