BASIC AND CLINICAL PHARMACOLOGY 15 BY
KATZUNG EXAM SCRIPT 2026 TEST PAPER
QUESTIONS AND SOLUTIONS GRADED A+
◉ How do antihistamines work?
Answer: Block the action of histamine at the H1 receptor
(H1 receptor release histamine are allergic response)
◉ What are antihistamines used for?
Answer: 1. Cold symptoms - decrease nasopharyngeal secretions
2. Allergic rhinitis - decrease nasal itching and tickling that cause
sneezing
3. Anaphylaxis
4. Drug allergies
5. Blood/blood product transfusion reaction
6. Dermatologic conditions
7. Motion sickness, nausea, vomiting, and sedation
◉ Prototype of antihistamine:
Answer: diphenhydramine (Benadryl)
, ◉ First-generation antihistamine (diphenhydramine, Benadryl)
cause:
Answer: Dry mouth and drowsiness
◉ What is a second-generation antihistamines?
Answer: Cetirizine (Zyrtec)
Ioratadine (Claritin)
( Dont cause as much sedation as first-generation)
◉ Benadryl does not make children excited. T/F
Answer: False, it can make small children excitable
◉ Benadryl can cause an allergic reaction. T/F
Answer: True, especially in IM or IV
◉ Benadryl is not used for nausea or motion sickness. T/F
Answer: False, Benadryl is also used for nausea and motion sickness.
◉ Astelin (nasal spray) has no systemic effects.
Answer: True
◉ What is nursing care for antihistamines?
KATZUNG EXAM SCRIPT 2026 TEST PAPER
QUESTIONS AND SOLUTIONS GRADED A+
◉ How do antihistamines work?
Answer: Block the action of histamine at the H1 receptor
(H1 receptor release histamine are allergic response)
◉ What are antihistamines used for?
Answer: 1. Cold symptoms - decrease nasopharyngeal secretions
2. Allergic rhinitis - decrease nasal itching and tickling that cause
sneezing
3. Anaphylaxis
4. Drug allergies
5. Blood/blood product transfusion reaction
6. Dermatologic conditions
7. Motion sickness, nausea, vomiting, and sedation
◉ Prototype of antihistamine:
Answer: diphenhydramine (Benadryl)
, ◉ First-generation antihistamine (diphenhydramine, Benadryl)
cause:
Answer: Dry mouth and drowsiness
◉ What is a second-generation antihistamines?
Answer: Cetirizine (Zyrtec)
Ioratadine (Claritin)
( Dont cause as much sedation as first-generation)
◉ Benadryl does not make children excited. T/F
Answer: False, it can make small children excitable
◉ Benadryl can cause an allergic reaction. T/F
Answer: True, especially in IM or IV
◉ Benadryl is not used for nausea or motion sickness. T/F
Answer: False, Benadryl is also used for nausea and motion sickness.
◉ Astelin (nasal spray) has no systemic effects.
Answer: True
◉ What is nursing care for antihistamines?
