NR 565 - advanced pharmacology midterm -
Chamberlain
Terms in this set (244)
During what trimester is a pregnant 1st trimester (fetus most at risk d/t rapid growth)
woman most at risk for adverse drug
reactions with potential long term
consequences?
What is BEERS criteria? Recommendations of medications inappropriate for
elderly (65 and older), prescriber ultimately decides
,What is the CYP450 (cytochrome P450) liver enzyme system where medications are
metabolized, can either be inducers or inhibitors and
create drug-drug interactions
CYP450 inducers Speed up metabolism of drugs (drug is cleared faster),
drug has lesser effect (decrease blood levels of drug),
elevate CYP450 enzymes
CYP450 inducers pneumonic "Bullshit Crap GPS INDUCES rage"
CYP450 inducer drug names Barbituates, St John wort, Carbamazepine, rifampin,
alcohol, phenytoin, griseofulvin, phenobarbital,
sulfonylureas
,CYP450 inhibitors inhibit metabolism, increase blood levels of
medications
CYP450 pneumonic "VISA credit card debt INHIBITS spending on designers
like CK to look GQ"
CYP450 inhibitors drug names Valproate, isoniazid, sulfonamides, amiodarone,
chloramphenicol, ketoconazole, grapefruit juice,
quinidine
Physiological changes during increase glomerular filtration rate leads to increase
pregnancy that impact durg excretion
pharmacodynamics and increase hepatic metabolism
pharmacokinetic properties of drugs? decrease tone and motility of bowel
increase drug absorption
, Examples of medications that can be Antiepileptic drugs, antimicrobials such as tetracyclines
teratogenic and fluoroquinolones, vitamin A in large doses, some
anticoagulants, and hormonal medications such as
diethylstilbestrol (DES).
How is absorption of intramuscular slow and erratic due to low blood flow in muscles first
medications different in neonates? few days of life
Why is absorption of medication in the delayed gastric emptying
stomach increased in infancy?
Some medications that should be glucocorticoids, discoloration of developing teeth with
avoided in the pediatric patient? tetracyclines, and kernicterus with sulfonamides,
levofloxacin (antibiotics)
aspirin (Severe intoxication from acute overdose)
Chamberlain
Terms in this set (244)
During what trimester is a pregnant 1st trimester (fetus most at risk d/t rapid growth)
woman most at risk for adverse drug
reactions with potential long term
consequences?
What is BEERS criteria? Recommendations of medications inappropriate for
elderly (65 and older), prescriber ultimately decides
,What is the CYP450 (cytochrome P450) liver enzyme system where medications are
metabolized, can either be inducers or inhibitors and
create drug-drug interactions
CYP450 inducers Speed up metabolism of drugs (drug is cleared faster),
drug has lesser effect (decrease blood levels of drug),
elevate CYP450 enzymes
CYP450 inducers pneumonic "Bullshit Crap GPS INDUCES rage"
CYP450 inducer drug names Barbituates, St John wort, Carbamazepine, rifampin,
alcohol, phenytoin, griseofulvin, phenobarbital,
sulfonylureas
,CYP450 inhibitors inhibit metabolism, increase blood levels of
medications
CYP450 pneumonic "VISA credit card debt INHIBITS spending on designers
like CK to look GQ"
CYP450 inhibitors drug names Valproate, isoniazid, sulfonamides, amiodarone,
chloramphenicol, ketoconazole, grapefruit juice,
quinidine
Physiological changes during increase glomerular filtration rate leads to increase
pregnancy that impact durg excretion
pharmacodynamics and increase hepatic metabolism
pharmacokinetic properties of drugs? decrease tone and motility of bowel
increase drug absorption
, Examples of medications that can be Antiepileptic drugs, antimicrobials such as tetracyclines
teratogenic and fluoroquinolones, vitamin A in large doses, some
anticoagulants, and hormonal medications such as
diethylstilbestrol (DES).
How is absorption of intramuscular slow and erratic due to low blood flow in muscles first
medications different in neonates? few days of life
Why is absorption of medication in the delayed gastric emptying
stomach increased in infancy?
Some medications that should be glucocorticoids, discoloration of developing teeth with
avoided in the pediatric patient? tetracyclines, and kernicterus with sulfonamides,
levofloxacin (antibiotics)
aspirin (Severe intoxication from acute overdose)
