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MMSC436 FINAL EXAM POTENTIAL
QUESTIONS AND ANSWERS
The three levels of dysfunction that may be evaluated in a patient
with an endocrine problem are primary, secondary, and tertiary.
The possible defective sites that correspond to these primary,
secondary, and tertiary levels of dysfunction are, respectively


A. Pituitary, target gland, hypothalamus
B. Hypothalamus, target gland, pituitary
C. Pituitary, hypothalamus, target gland
D. Target gland, pituitary, hypothalamus
E. Target gland, hypothalamus, pituitary -
correct answer ✅Target gland, pituitary, hypothalamus


Pituitary secretion of adrenocorticotropic hormone (ACTH) is
inhibited by elevated levels of:


a. Aldosterone
b. Cortisol
c. Estradiol-17b
d. Progesterone
e. Epinephrine -
correct answer ✅cortisol

,MMSC436 FINAL EXAM POTENTIAL
QUESTIONS AND ANSWERS

An example of ectopic hormone production would be:


a. Prolactin production by pituitary tumors
b. Corticotropin releasing hormone from hypothalamus
c. Growth hormone production by lung tumors
d. Growth hormone production by pituitary tumors -
correct answer ✅growth hormone production by lung tumors


The definitive diagnosis of primary adrenal insufficiency requires
demonstration of:


a. Decreased urinary 17-keto and 17-hydroxysteroids
b. Decreased cortisol production
c. Impaired response to ACTH stimulation
d. Increased urinary cortisol excretion after metyrapone (inhibitor)
treatment -
correct answer ✅impaired response to ACTH stimulation

, MMSC436 FINAL EXAM POTENTIAL
QUESTIONS AND ANSWERS
As a screening test for Cushing's syndrome, the physician wishes to
see whether a patient exhibits normal diurnal rhythm of his cortisol
secretion. At what time should the specimens be drawn for plasma
cortisol determination? (daytime work schedule)


a. 6 am, noon
b. 8 am, 2 pm
c. 8am, 6pm
d. Noon, 6pm -
correct answer ✅8am, 6pm


The parent substance of all steroid hormones
a. Cortisol
b. Catecholamines
c. Progesterone
d. Cholesterol
e. Amino acids -
correct answer ✅cholesterol


Which is normally the most abundant corticosteroid hormone
secreted by the adrenal cortex?

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