ANP 1106 Midterm Exam Prep Document | 2026/2027 Edition
| 200 Verified Questions - 151 Questions with Answers
ANP 1106 Midterm 1, Midterm 2 & Final Bundled Exam 2026-151 QUESTIONS AND ANSWERS ALREADY
GRADED A+. 100% Verified Solutions | Updated Per Latest Guidelines | Graded A+
This comprehensive exam preparation bundle for ANP 1106 (Human Anatomy and Physiology)
consolidates actual and practice exams for Midterm 1, Midterm 2, and the Final, featuring 200 verified
questions and answers. Designed to align with the 2026/2027 academic year curriculum, this resource
covers all major systems and concepts, ensuring thorough preparation. Each question is accompanied
by a detailed rationale and correct answer, facilitating deep understanding and retention. Ideal for
students aiming for a top grade, this bundle reflects the latest exam patterns and guidelines.
Key Features:
Introduction to Human Anatomy and Physiology: anatomical terminology, body organization, homeostasis
Cellular Biology: cell structure, organelles, membrane transport, cell division
Tissues: epithelial, connective, muscle, nervous tissues; structure and function
Integumentary System: skin layers, accessory structures, functions, repair
Skeletal System: bone tissue, axial and appendicular skeleton, joints, bone development
Muscular System: muscle tissue types, skeletal muscle anatomy, contraction mechanism, energy metabolism
Nervous System: neurons, neuroglia, action potentials, synapses, CNS and PNS organization
Spinal Cord and Spinal Nerves: structure, reflexes, nerve plexuses
Brain and Cranial Nerves: brain regions, ventricles, cranial nerves, higher functions
Autonomic Nervous System: sympathetic and parasympathetic divisions, neurotransmitters
Sensory Systems: general senses, receptors, pathways; special senses (vision, hearing, taste, smell)
Endocrine System: hormones, endocrine glands, feedback loops, major hormones
Cardiovascular System: blood, heart anatomy, cardiac cycle, blood vessels, hemodynamics
Lymphatic System and Immunity: lymphatic vessels, organs, innate and adaptive immunity
Respiratory System: anatomy, ventilation, gas exchange, transport, regulation
Digestive System: anatomy, digestive processes, regulation, nutrition and metabolism
Urinary System: kidney anatomy, nephron function, urine formation, fluid and electrolyte balance
Fluid, Electrolyte, and Acid-Base Balance: compartments, buffers, renal and respiratory regulation
Updates for 2026:
- Updated to reflect the latest 2026/2027 academic year curriculum changes
- Incorporated new clinical correlations and case studies
- Enhanced answer rationales with evidence-based explanations
- Revised practice questions to mirror recent exam trends
- Added comprehensive coverage of emerging topics in physiology
Abstract:
This exam preparation bundle for ANP 1106 (Human Anatomy and Physiology) provides a rigorous and
comprehensive review of the entire course curriculum, spanning from basic cellular biology to complex systemic
interactions. With 200 verified questions distributed across Midterm 1, Midterm 2, and the Final, this resource
ensures extensive practice and mastery of key concepts. Each question is meticulously answered and explained,
offering insights into the physiological mechanisms and anatomical structures. The content is organized to follow
the logical progression of the course, facilitating systematic study. Updated for the 2026/2027 academic year, this
bundle integrates current educational standards and assessment formats. It is an indispensable tool for students
Page 1
,seeking to excel in their examinations and achieve a thorough understanding of human anatomy and physiology.
Keywords:
ANP 1106, Human Anatomy and Physiology, Midterm Exam, Final Exam, Verified Questions, 2026/2027, Practice
Exams, Graded A+
Answer Format:
Each question is presented in multiple-choice format with four options. The correct answer is clearly indicated,
followed by a detailed rationale explaining why it is correct and why the distractors are incorrect. This format
reinforces learning and clarifies common misconceptions.
Compliance Checklist:
Aligned with the official ANP 1106 syllabus for 2026/2027
Questions verified for accuracy by subject matter experts
Includes both actual exam questions and practice questions
Answers and rationales updated per latest guidelines
Suitable for self-assessment and exam simulation
Content Area Overview:
Content Area Questions Key Topics Weight
Introduction and Cells 1-20 Anatomical terminology, homeostasis, cell 10%
structure, membrane transport
Tissues and Integumentary 21-40 Epithelial, connective, muscle, nervous 10%
System tissues; skin and accessory structures
Skeletal System 41-60 Bone tissue, axial and appendicular skeleton, 10%
joints
Muscular System 61-80 Muscle tissue types, skeletal muscle 10%
anatomy, contraction, energy metabolism
Nervous System 81-110 Neurons, action potentials, synapses, CNS, 15%
PNS, spinal cord, brain, cranial nerves, ANS
Sensory Systems 111-130 General senses, receptors, special senses 10%
(vision, hearing, taste, smell)
Endocrine System 131-150 Hormones, endocrine glands, feedback 10%
loops, major hormones
Cardiovascular and Lymphatic 151-170 Blood, heart, blood vessels, cardiac cycle, 10%
Systems immunity
Respiratory and Digestive 171-185 Respiratory anatomy and physiology, 8%
Systems digestive processes, nutrition
Urinary and Fluid Balance 186-200 Kidney anatomy, nephron function, urine 7%
formation, fluid and electrolyte balance
Page 2
,Q1. In a neuron, the Na+/K+-ATPase is inhibited. Which of the following immediate
changes would occur in the resting membrane potential and the concentration
gradients of Na+ and K+?
A. The resting membrane potential becomes less negative, and the Na+ and K+
gradients slowly dissipate.
B. The resting membrane potential becomes more negative, and the Na+ and K+
gradients increase.
C. The resting membrane potential remains unchanged, but the Na+ gradient reverses.
D. The resting membrane potential becomes zero, and the gradients are abolished
instantly.
Correct Answer: A. The resting membrane potential becomes less negative, and the
Na+ and K+ gradients slowly dissipate.
Rationale: The Na+/K+-ATPase maintains the low intracellular Na+ and high
intracellular K+ concentrations. Inhibition causes gradual dissipation of these gradients,
making the resting membrane potential less negative (depolarized) as K+ leaks out and
Na+ leaks in. The gradients do not reverse, and the membrane potential does not
immediately become zero.
Why Wrong:
B - Inhibition of the pump would not hyperpolarize or increase gradients; it would
dissipate them.
C - Gradients do not reverse; they slowly dissipate.
D - The change is gradual, not instantaneous, and the membrane potential would not
reach exactly zero.
Reference: Boron, W.F., & Boulpaep, E.L. (2025). Medical Physiology, 4th Ed., Ch. 6.
Q2. Which of the following correctly describes the sequence of electrical events in the
heart during a normal cardiac cycle, from the SA node to ventricular contraction?
A. SA node -> AV node -> Bundle of His -> Purkinje fibers -> ventricular
depolarization
B. SA node -> Bundle of His -> AV node -> Purkinje fibers -> ventricular
depolarization
C. SA node -> AV node -> Purkinje fibers -> Bundle of His -> ventricular
depolarization
D. AV node -> SA node -> Bundle of His -> Purkinje fibers -> ventricular
depolarization
Correct Answer: A. SA node -> AV node -> Bundle of His -> Purkinje fibers ->
ventricular depolarization
Rationale: The cardiac conduction system follows a strict order: SA node (pacemaker) !’
AV node (delay) -> Bundle of His -> bundle branches -> Purkinje fibers, which then
Page 3
, stimulate ventricular depolarization. This ensures coordinated atrial contraction followed
by ventricular contraction.
Why Wrong:
B - The Bundle of His is distal to the AV node, not before it.
C - Purkinje fibers are distal to the Bundle of His, not before it.
D - The SA node is the primary pacemaker and initiates the sequence, not the AV
node.
Reference: Guyton, A.C., & Hall, J.E. (2025). Textbook of Medical Physiology, 15th Ed.,
Ch. 10.
Q3. During an isometric contraction of skeletal muscle, which of the following events
occurs at the sarcomere level?
A. Cross-bridges cycle, but the muscle length remains constant and tension increases.
B. Cross-bridges detach and the sarcomere shortens.
C. The Z-lines move closer together, but no tension is generated.
D. Calcium is not released from the sarcoplasmic reticulum.
Correct Answer: A. Cross-bridges cycle, but the muscle length remains constant and
tension increases.
Rationale: In isometric contraction, the muscle generates tension without changing length.
At the sarcomere level, cross-bridges form and cycle, producing force, but the sarcomere
does not shorten. Calcium is released and cross-bridges are active.
Why Wrong:
B - Sarcomere shortening occurs in isotonic contraction, not isometric.
C - Z-lines move closer only when sarcomere shortens, which does not happen in
isometric.
D - Calcium is essential for contraction and is released regardless of contraction type.
Reference: Sherwood, L. (2026). Human Physiology: From Cells to Systems, 10th Ed., Ch.
8.
Q4. Which of the following would most likely result from a complete transection of
the spinal cord at the level of C3?
A. Immediate loss of all voluntary movement and sensation below the neck, but
respiratory function is preserved.
B. Loss of diaphragmatic breathing due to phrenic nerve paralysis, leading to
respiratory failure.
C. Paralysis of the lower limbs only, with preservation of upper limb function.
D. Loss of sensation in the upper limbs but preservation of motor function in the lower
limbs.
Correct Answer: B. Loss of diaphragmatic breathing due to phrenic nerve paralysis,
Page 4
| 200 Verified Questions - 151 Questions with Answers
ANP 1106 Midterm 1, Midterm 2 & Final Bundled Exam 2026-151 QUESTIONS AND ANSWERS ALREADY
GRADED A+. 100% Verified Solutions | Updated Per Latest Guidelines | Graded A+
This comprehensive exam preparation bundle for ANP 1106 (Human Anatomy and Physiology)
consolidates actual and practice exams for Midterm 1, Midterm 2, and the Final, featuring 200 verified
questions and answers. Designed to align with the 2026/2027 academic year curriculum, this resource
covers all major systems and concepts, ensuring thorough preparation. Each question is accompanied
by a detailed rationale and correct answer, facilitating deep understanding and retention. Ideal for
students aiming for a top grade, this bundle reflects the latest exam patterns and guidelines.
Key Features:
Introduction to Human Anatomy and Physiology: anatomical terminology, body organization, homeostasis
Cellular Biology: cell structure, organelles, membrane transport, cell division
Tissues: epithelial, connective, muscle, nervous tissues; structure and function
Integumentary System: skin layers, accessory structures, functions, repair
Skeletal System: bone tissue, axial and appendicular skeleton, joints, bone development
Muscular System: muscle tissue types, skeletal muscle anatomy, contraction mechanism, energy metabolism
Nervous System: neurons, neuroglia, action potentials, synapses, CNS and PNS organization
Spinal Cord and Spinal Nerves: structure, reflexes, nerve plexuses
Brain and Cranial Nerves: brain regions, ventricles, cranial nerves, higher functions
Autonomic Nervous System: sympathetic and parasympathetic divisions, neurotransmitters
Sensory Systems: general senses, receptors, pathways; special senses (vision, hearing, taste, smell)
Endocrine System: hormones, endocrine glands, feedback loops, major hormones
Cardiovascular System: blood, heart anatomy, cardiac cycle, blood vessels, hemodynamics
Lymphatic System and Immunity: lymphatic vessels, organs, innate and adaptive immunity
Respiratory System: anatomy, ventilation, gas exchange, transport, regulation
Digestive System: anatomy, digestive processes, regulation, nutrition and metabolism
Urinary System: kidney anatomy, nephron function, urine formation, fluid and electrolyte balance
Fluid, Electrolyte, and Acid-Base Balance: compartments, buffers, renal and respiratory regulation
Updates for 2026:
- Updated to reflect the latest 2026/2027 academic year curriculum changes
- Incorporated new clinical correlations and case studies
- Enhanced answer rationales with evidence-based explanations
- Revised practice questions to mirror recent exam trends
- Added comprehensive coverage of emerging topics in physiology
Abstract:
This exam preparation bundle for ANP 1106 (Human Anatomy and Physiology) provides a rigorous and
comprehensive review of the entire course curriculum, spanning from basic cellular biology to complex systemic
interactions. With 200 verified questions distributed across Midterm 1, Midterm 2, and the Final, this resource
ensures extensive practice and mastery of key concepts. Each question is meticulously answered and explained,
offering insights into the physiological mechanisms and anatomical structures. The content is organized to follow
the logical progression of the course, facilitating systematic study. Updated for the 2026/2027 academic year, this
bundle integrates current educational standards and assessment formats. It is an indispensable tool for students
Page 1
,seeking to excel in their examinations and achieve a thorough understanding of human anatomy and physiology.
Keywords:
ANP 1106, Human Anatomy and Physiology, Midterm Exam, Final Exam, Verified Questions, 2026/2027, Practice
Exams, Graded A+
Answer Format:
Each question is presented in multiple-choice format with four options. The correct answer is clearly indicated,
followed by a detailed rationale explaining why it is correct and why the distractors are incorrect. This format
reinforces learning and clarifies common misconceptions.
Compliance Checklist:
Aligned with the official ANP 1106 syllabus for 2026/2027
Questions verified for accuracy by subject matter experts
Includes both actual exam questions and practice questions
Answers and rationales updated per latest guidelines
Suitable for self-assessment and exam simulation
Content Area Overview:
Content Area Questions Key Topics Weight
Introduction and Cells 1-20 Anatomical terminology, homeostasis, cell 10%
structure, membrane transport
Tissues and Integumentary 21-40 Epithelial, connective, muscle, nervous 10%
System tissues; skin and accessory structures
Skeletal System 41-60 Bone tissue, axial and appendicular skeleton, 10%
joints
Muscular System 61-80 Muscle tissue types, skeletal muscle 10%
anatomy, contraction, energy metabolism
Nervous System 81-110 Neurons, action potentials, synapses, CNS, 15%
PNS, spinal cord, brain, cranial nerves, ANS
Sensory Systems 111-130 General senses, receptors, special senses 10%
(vision, hearing, taste, smell)
Endocrine System 131-150 Hormones, endocrine glands, feedback 10%
loops, major hormones
Cardiovascular and Lymphatic 151-170 Blood, heart, blood vessels, cardiac cycle, 10%
Systems immunity
Respiratory and Digestive 171-185 Respiratory anatomy and physiology, 8%
Systems digestive processes, nutrition
Urinary and Fluid Balance 186-200 Kidney anatomy, nephron function, urine 7%
formation, fluid and electrolyte balance
Page 2
,Q1. In a neuron, the Na+/K+-ATPase is inhibited. Which of the following immediate
changes would occur in the resting membrane potential and the concentration
gradients of Na+ and K+?
A. The resting membrane potential becomes less negative, and the Na+ and K+
gradients slowly dissipate.
B. The resting membrane potential becomes more negative, and the Na+ and K+
gradients increase.
C. The resting membrane potential remains unchanged, but the Na+ gradient reverses.
D. The resting membrane potential becomes zero, and the gradients are abolished
instantly.
Correct Answer: A. The resting membrane potential becomes less negative, and the
Na+ and K+ gradients slowly dissipate.
Rationale: The Na+/K+-ATPase maintains the low intracellular Na+ and high
intracellular K+ concentrations. Inhibition causes gradual dissipation of these gradients,
making the resting membrane potential less negative (depolarized) as K+ leaks out and
Na+ leaks in. The gradients do not reverse, and the membrane potential does not
immediately become zero.
Why Wrong:
B - Inhibition of the pump would not hyperpolarize or increase gradients; it would
dissipate them.
C - Gradients do not reverse; they slowly dissipate.
D - The change is gradual, not instantaneous, and the membrane potential would not
reach exactly zero.
Reference: Boron, W.F., & Boulpaep, E.L. (2025). Medical Physiology, 4th Ed., Ch. 6.
Q2. Which of the following correctly describes the sequence of electrical events in the
heart during a normal cardiac cycle, from the SA node to ventricular contraction?
A. SA node -> AV node -> Bundle of His -> Purkinje fibers -> ventricular
depolarization
B. SA node -> Bundle of His -> AV node -> Purkinje fibers -> ventricular
depolarization
C. SA node -> AV node -> Purkinje fibers -> Bundle of His -> ventricular
depolarization
D. AV node -> SA node -> Bundle of His -> Purkinje fibers -> ventricular
depolarization
Correct Answer: A. SA node -> AV node -> Bundle of His -> Purkinje fibers ->
ventricular depolarization
Rationale: The cardiac conduction system follows a strict order: SA node (pacemaker) !’
AV node (delay) -> Bundle of His -> bundle branches -> Purkinje fibers, which then
Page 3
, stimulate ventricular depolarization. This ensures coordinated atrial contraction followed
by ventricular contraction.
Why Wrong:
B - The Bundle of His is distal to the AV node, not before it.
C - Purkinje fibers are distal to the Bundle of His, not before it.
D - The SA node is the primary pacemaker and initiates the sequence, not the AV
node.
Reference: Guyton, A.C., & Hall, J.E. (2025). Textbook of Medical Physiology, 15th Ed.,
Ch. 10.
Q3. During an isometric contraction of skeletal muscle, which of the following events
occurs at the sarcomere level?
A. Cross-bridges cycle, but the muscle length remains constant and tension increases.
B. Cross-bridges detach and the sarcomere shortens.
C. The Z-lines move closer together, but no tension is generated.
D. Calcium is not released from the sarcoplasmic reticulum.
Correct Answer: A. Cross-bridges cycle, but the muscle length remains constant and
tension increases.
Rationale: In isometric contraction, the muscle generates tension without changing length.
At the sarcomere level, cross-bridges form and cycle, producing force, but the sarcomere
does not shorten. Calcium is released and cross-bridges are active.
Why Wrong:
B - Sarcomere shortening occurs in isotonic contraction, not isometric.
C - Z-lines move closer only when sarcomere shortens, which does not happen in
isometric.
D - Calcium is essential for contraction and is released regardless of contraction type.
Reference: Sherwood, L. (2026). Human Physiology: From Cells to Systems, 10th Ed., Ch.
8.
Q4. Which of the following would most likely result from a complete transection of
the spinal cord at the level of C3?
A. Immediate loss of all voluntary movement and sensation below the neck, but
respiratory function is preserved.
B. Loss of diaphragmatic breathing due to phrenic nerve paralysis, leading to
respiratory failure.
C. Paralysis of the lower limbs only, with preservation of upper limb function.
D. Loss of sensation in the upper limbs but preservation of motor function in the lower
limbs.
Correct Answer: B. Loss of diaphragmatic breathing due to phrenic nerve paralysis,
Page 4
