imatinib
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BCR-Abl TK is a blood cancer
Imatinib is a tyrosine kinase inhibitor of the blood cancer
inhibits phosphorylation of TK enzyme
works via H bonds and van der waals forces
anti cancer effect
lidocane
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, - highly expressed in several tissues
- local anesthetic
- widespread adverse effects in CNS and heart if drug reaches systemic
circulation
nature of drugs (state at room temperature)
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most are solid ie) aspirin
some are liquids ie) ethanol, nicotine, inhalant anesthetics
few are gases ie) nitrous oxide
signal transduction pathway (3 components)
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1) receptor
2) cellular target
3) intermediary molecules
"receptor-effector coupling mechanism"
what two types of drugs do not act on receptors
Give this one a try later!
Give this one a try later!
BCR-Abl TK is a blood cancer
Imatinib is a tyrosine kinase inhibitor of the blood cancer
inhibits phosphorylation of TK enzyme
works via H bonds and van der waals forces
anti cancer effect
lidocane
Give this one a try later!
, - highly expressed in several tissues
- local anesthetic
- widespread adverse effects in CNS and heart if drug reaches systemic
circulation
nature of drugs (state at room temperature)
Give this one a try later!
most are solid ie) aspirin
some are liquids ie) ethanol, nicotine, inhalant anesthetics
few are gases ie) nitrous oxide
signal transduction pathway (3 components)
Give this one a try later!
1) receptor
2) cellular target
3) intermediary molecules
"receptor-effector coupling mechanism"
what two types of drugs do not act on receptors
Give this one a try later!
