Mechanism of action for Nitrate vasodilators?
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Involves conversion of nitrate or nitrite groupS to nitric oxide (NO) —>
increase cGMP = relaxation of smooth muscle in vessels (vasodilation)
Class II Anti-arrhythmics
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Beta blockers
Block catecholamine actions at beta-1 receptor in AV node
Prolong conduction through AV node and slow down HR
Best for Atrial arrhythmias
, propranolol and metroprolol
What happens to F-S curve when a patient with HF is treated with a positive ion
trope?
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Digitalis (positive inotrope) will shift curve upward and increase CO
wont return to a normal healthy heart but will be better
GABA
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Neutral amino acid
Inhibitory
Associated with behaviour
Acts on postsynaptic GABA receptors such as GABAA and GABAB
renin
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hormone secreted by the kidney; it raises blood pressure by influencing
vasoconstriction (narrowing of blood vessels)
, cleaves angiostensinogen -->angiostensin I
Role of Ca2+ in blood vessel constriction
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Ca2+ activates myosin to bind actin and cause muscle contraction = vessel
contriction
Where is aldosterone secreted from?
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zona glomerulosa cells of adrenal gland
Levodopa
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Dopamine agonist used to treat PD
Metoprolol
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, B1-Selective adrenergic antagonist
Used for arrhythmias to slow HR
Healthy blood pressure
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120/80 or less
Four stages of developing heart failure
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Class 1 (mild) - no limitation
-treated with ACE inhibitors (enapril), ARBs (losartan), Thiazide diuretics or
loop
Class II (mild) - slight limitation; comfortable at rest, ordinary physical
activity results in fatigue, palpitation, or dyspnea
Class III (moderate) - marked limitation of physical activity, comfortable at
rest, less than ordinary activity causes fatigue, palpitation, or dypnea
Class IV (severe) - unable to carry out physical activity without discomfort,
symptoms at rest and worsen with activity
Ex of a neurohormonal regulator
Give this one a try later!
Give this one a try later!
Involves conversion of nitrate or nitrite groupS to nitric oxide (NO) —>
increase cGMP = relaxation of smooth muscle in vessels (vasodilation)
Class II Anti-arrhythmics
Give this one a try later!
Beta blockers
Block catecholamine actions at beta-1 receptor in AV node
Prolong conduction through AV node and slow down HR
Best for Atrial arrhythmias
, propranolol and metroprolol
What happens to F-S curve when a patient with HF is treated with a positive ion
trope?
Give this one a try later!
Digitalis (positive inotrope) will shift curve upward and increase CO
wont return to a normal healthy heart but will be better
GABA
Give this one a try later!
Neutral amino acid
Inhibitory
Associated with behaviour
Acts on postsynaptic GABA receptors such as GABAA and GABAB
renin
Give this one a try later!
hormone secreted by the kidney; it raises blood pressure by influencing
vasoconstriction (narrowing of blood vessels)
, cleaves angiostensinogen -->angiostensin I
Role of Ca2+ in blood vessel constriction
Give this one a try later!
Ca2+ activates myosin to bind actin and cause muscle contraction = vessel
contriction
Where is aldosterone secreted from?
Give this one a try later!
zona glomerulosa cells of adrenal gland
Levodopa
Give this one a try later!
Dopamine agonist used to treat PD
Metoprolol
Give this one a try later!
, B1-Selective adrenergic antagonist
Used for arrhythmias to slow HR
Healthy blood pressure
Give this one a try later!
120/80 or less
Four stages of developing heart failure
Give this one a try later!
Class 1 (mild) - no limitation
-treated with ACE inhibitors (enapril), ARBs (losartan), Thiazide diuretics or
loop
Class II (mild) - slight limitation; comfortable at rest, ordinary physical
activity results in fatigue, palpitation, or dyspnea
Class III (moderate) - marked limitation of physical activity, comfortable at
rest, less than ordinary activity causes fatigue, palpitation, or dypnea
Class IV (severe) - unable to carry out physical activity without discomfort,
symptoms at rest and worsen with activity
Ex of a neurohormonal regulator
Give this one a try later!