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BIOM 3090 FINAL EXAM QUESTIONS AND CORRECT ANSWERS

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BIOM 3090 FINAL EXAM QUESTIONS AND CORRECT ANSWERS

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Mechanism of action for Nitrate vasodilators?


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Involves conversion of nitrate or nitrite groupS to nitric oxide (NO) —>
increase cGMP = relaxation of smooth muscle in vessels (vasodilation)




Class II Anti-arrhythmics


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Beta blockers

Block catecholamine actions at beta-1 receptor in AV node

Prolong conduction through AV node and slow down HR

Best for Atrial arrhythmias

, propranolol and metroprolol




What happens to F-S curve when a patient with HF is treated with a positive ion
trope?


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Digitalis (positive inotrope) will shift curve upward and increase CO


wont return to a normal healthy heart but will be better




GABA


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Neutral amino acid


Inhibitory

Associated with behaviour

Acts on postsynaptic GABA receptors such as GABAA and GABAB




renin


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hormone secreted by the kidney; it raises blood pressure by influencing
vasoconstriction (narrowing of blood vessels)

, cleaves angiostensinogen -->angiostensin I




Role of Ca2+ in blood vessel constriction


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Ca2+ activates myosin to bind actin and cause muscle contraction = vessel
contriction




Where is aldosterone secreted from?


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zona glomerulosa cells of adrenal gland




Levodopa


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Dopamine agonist used to treat PD




Metoprolol


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, B1-Selective adrenergic antagonist

Used for arrhythmias to slow HR




Healthy blood pressure


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120/80 or less




Four stages of developing heart failure


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Class 1 (mild) - no limitation
-treated with ACE inhibitors (enapril), ARBs (losartan), Thiazide diuretics or
loop

Class II (mild) - slight limitation; comfortable at rest, ordinary physical
activity results in fatigue, palpitation, or dyspnea

Class III (moderate) - marked limitation of physical activity, comfortable at
rest, less than ordinary activity causes fatigue, palpitation, or dypnea

Class IV (severe) - unable to carry out physical activity without discomfort,
symptoms at rest and worsen with activity




Ex of a neurohormonal regulator


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