iHuman Advanced DDx Comprehensive Study Guide: Dan
Jones – A 42-Year-Old Male with Acute Diarrhea. Complete
Clinical Simulation, Gastrointestinal & Systemic Assessment,
Differential Diagnosis, and Evidence-Based Management |
Graded A+ | 2026/2027 Update
,Case Overview
Attribute Detail
Patient Dan Jones, 42-year-old male
,Attribute Detail
Height/Weight 5'10" (178 cm), 180.0 lb (81.8 kg)
BMI 25.8 kg/m² (overweight)
Occupation Office administrator
Reason for Encounter Diarrhea
Mode Advanced DDx Test Mode (no real-time feedback)
Chief Complaint & History of Presenting Illness (HPI)
Chief Complaint: "I've had loose watery stools since three days ago — about 6 to 8 times
a day — and I feel weak."
OLD CARTS Framework
Component Detail Clinical Significance
Onset Sudden, 3 days ago Suggests acute infectious process
Location Diffuse lower abdominal cramping Non-localizing, consistent with gastroente
Duration 3 days continuous Acute (<14 days) = likely infectious
Character Watery, non-bloody, non-mucoid Suggests viral or toxin-mediated etiology
Aggravating Eating, movement Increased peristalsis with eating
Relieving None significant Persistent symptoms requiring care
Timing Continuous day and night No diurnal variation
Severity Moderate; interfering with daily activities Functional impact
, Associated Symptoms
Symptom Present Detail
Nausea Yes Present throughout day; no vomiting
Vomiting No Notable absence (vomiting is prominent in norovirus)
Abdominal Cramping Yes Diffuse, mild, non-localizing
Fever Subjective Feels warm; no chills/rigors
Weakness/Fatigue Yes Significant; took 2 days off work
Lightheadedness Yes Upon standing; orthostatic
Blood in Stool No Less likely invasive bacterial infection
Weight Loss No Acute process less likely to cause significant weight loss
Recent Exposures
• Food History: Ate at local restaurant 2 days prior to symptom onset
• Household Contacts: No illness in family
• Travel History: None in past 6 months
• Antibiotic Exposure: None in past 6 months
• Healthcare Exposure: None
Review of Systems (ROS)
Constitutional
• Fever: Subjective feeling of warmth; denies chills, rigors, night sweats
• Fatigue: Present, significant
• Weight: Denies unintentional weight loss
Jones – A 42-Year-Old Male with Acute Diarrhea. Complete
Clinical Simulation, Gastrointestinal & Systemic Assessment,
Differential Diagnosis, and Evidence-Based Management |
Graded A+ | 2026/2027 Update
,Case Overview
Attribute Detail
Patient Dan Jones, 42-year-old male
,Attribute Detail
Height/Weight 5'10" (178 cm), 180.0 lb (81.8 kg)
BMI 25.8 kg/m² (overweight)
Occupation Office administrator
Reason for Encounter Diarrhea
Mode Advanced DDx Test Mode (no real-time feedback)
Chief Complaint & History of Presenting Illness (HPI)
Chief Complaint: "I've had loose watery stools since three days ago — about 6 to 8 times
a day — and I feel weak."
OLD CARTS Framework
Component Detail Clinical Significance
Onset Sudden, 3 days ago Suggests acute infectious process
Location Diffuse lower abdominal cramping Non-localizing, consistent with gastroente
Duration 3 days continuous Acute (<14 days) = likely infectious
Character Watery, non-bloody, non-mucoid Suggests viral or toxin-mediated etiology
Aggravating Eating, movement Increased peristalsis with eating
Relieving None significant Persistent symptoms requiring care
Timing Continuous day and night No diurnal variation
Severity Moderate; interfering with daily activities Functional impact
, Associated Symptoms
Symptom Present Detail
Nausea Yes Present throughout day; no vomiting
Vomiting No Notable absence (vomiting is prominent in norovirus)
Abdominal Cramping Yes Diffuse, mild, non-localizing
Fever Subjective Feels warm; no chills/rigors
Weakness/Fatigue Yes Significant; took 2 days off work
Lightheadedness Yes Upon standing; orthostatic
Blood in Stool No Less likely invasive bacterial infection
Weight Loss No Acute process less likely to cause significant weight loss
Recent Exposures
• Food History: Ate at local restaurant 2 days prior to symptom onset
• Household Contacts: No illness in family
• Travel History: None in past 6 months
• Antibiotic Exposure: None in past 6 months
• Healthcare Exposure: None
Review of Systems (ROS)
Constitutional
• Fever: Subjective feeling of warmth; denies chills, rigors, night sweats
• Fatigue: Present, significant
• Weight: Denies unintentional weight loss
