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EMERGENCY NURSE PRACTITIONER (ENP) 400 Original Exam Questions & Answers

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EMERGENCY NURSE PRACTITIONER (ENP) 400 Original Exam Questions & Answers   Cardiology 1. Which of the following is correct regarding ACS first-line antiplatelet? A) Furosemide B) Metformin C) Warfarin D) Aspirin Answer: D) Aspirin Rationale: Aspirin is foundational early antiplatelet therapy in ACS when not contraindicated. Source basis: 2025 AHA/ACC/ACEP ACS Guideline 2. An emergency nurse practitioner is reviewing ACS first-line antiplatelet. Which statement is TRUE? A) Metformin B) Furosemide C) Warfarin D) Aspirin Answer: D) Aspirin Rationale: Aspirin is foundational early antiplatelet therapy in ACS when not contraindicated. Source basis: 2025 AHA/ACC/ACEP ACS Guideline 3. Which answer best describes the appropriate emergency-care principle for ACS first-line antiplatelet? A) Furosemide B) Warfarin C) Metformin D) Aspirin Answer: D) Aspirin Rationale: Aspirin is foundational early antiplatelet therapy in ACS when not contraindicated. Source basis: 2025 AHA/ACC/ACEP ACS Guideline 4. Which of the following is correct regarding STEMI reperfusion when timely PCI is available? A) Stress testing first B) Routine observation C) Primary PCI D) Oral antibiotics Answer: C) Primary PCI Rationale: Timely primary PCI is generally preferred when available. Source basis: 2025 AHA/ACC/ACEP ACS Guideline 5. An emergency nurse practitioner is reviewing STEMI reperfusion when timely PCI is available. Which statement is TRUE? A) Oral antibiotics B) Stress testing first C) Routine observation D) Primary PCI Answer: D) Primary PCI Rationale: Timely primary PCI is generally preferred when available. Source basis: 2025 AHA/ACC/ACEP ACS Guideline 6. Which answer best describes the appropriate emergency-care principle for STEMI reperfusion when timely PCI isavailable? A) Routine observation B) Primary PCI C) Stress testing first D) Oral antibiotics Answer: B) Primary PCI Rationale: Timely primary PCI is generally preferred when available. Source basis: 2025 AHA/ACC/ACEP ACS Guideline 7. Which of the following is correct regarding Major nitrate contraindication in ACS? A) Significant hypotension or recent PDE-5 inhibitor use B) Normal heart rate C) Age over 40 D) Mild nausea Answer: A) Significant hypotension or recent PDE-5 inhibitor use Rationale: Nitrates can cause dangerous hypotension in these settings. Source basis: Emergency cardiovascular guidance 8. An emergency nurse practitioner is reviewing Major nitrate contraindication in ACS. Which statement is TRUE? A) Normal heart rate B) Significant hypotension or recent PDE-5 inhibitor use C) Mild nausea D) Age over 40 Answer: B) Significant hypotension or recent PDE-5 inhibitor use Rationale: Nitrates can cause dangerous hypotension in these settings. Source basis: Emergency cardiovascular guidance 9. Which answer best describes the appropriate emergency-care principle for Major nitrate contraindication in ACS? A) Mild nausea B) Age over 40 C) Normal heart rate D) Significant hypotension or recent PDE-5 inhibitor use Answer: D) Significant hypotension or recent PDE-5 inhibitor use Rationale: Nitrates can cause dangerous hypotension in these settings. Source basis: Emergency cardiovascular guidance 10. Which of the following is correct regarding Inferior STEMI with hypotension and clear lungs? A) GERD B) Asthma C) Right ventricular infarction D) Migraine Answer: C) Right ventricular infarction Rationale: Inferior STEMI can involve the right ventricle and cause preload-dependent hypotension. Source basis: Emergency cardiology principles 11. An emergency nurse practitioner is reviewing Inferior STEMI with hypotension and clear lungs. Which statement is TRUE? A) GERD B) Right ventricular infarction C) Asthma D) Migraine Answer: B) Right ventricular infarction Rationale: Inferior STEMI can involve the right ventricle and cause preload-dependent hypotension. Source basis: Emergency cardiology principles 12. Which answer best describes the appropriate emergency-care principle for Inferior STEMI with hypotension and clearlungs? A) GERD B) Migraine C) Right ventricular infarction D) Asthma Answer: C) Right ventricular infarction Rationale: Inferior STEMI can involve the right ventricle and cause preload-dependent hypotension. Source basis: Emergency cardiology principles 13. Which of the following is correct regarding Abrupt severe chest/back pain with pulse asymmetry suggests? A) Pneumonia B) GERD C) Migraine D) Aortic dissection Answer: D) Aortic dissection Rationale: Abrupt severe pain plus pulse/BP asymmetry is a classic warning pattern. Source basis: ACEP thoracic aortic dissection policy 14. An emergency nurse practitioner is reviewing Abrupt severe chest/back pain with pulse asymmetry suggests. Whichstatement is TRUE? A) GERD B) Migraine C) Pneumonia D) Aortic dissection Answer: D) Aortic dissection Rationale: Abrupt severe pain plus pulse/BP asymmetry is a classic warning pattern. Source basis: ACEP thoracic aortic dissection policy 15. Which answer best describes the appropriate emergency-care principle for Abrupt severe chest/back pain with pulseasymmetry suggests? A) GERD B) Migraine C) Aortic dissection D) Pneumonia Answer: C) Aortic dissection Rationale: Abrupt severe pain plus pulse/BP asymmetry is a classic warning pattern. Source basis: ACEP thoracic aortic dissection policy 16. Which of the following is correct regarding Classic ECG pattern of acute pericarditis? A) Short QT B) Isolated Q waves C) Territorial ST elevation only D) Diffuse ST elevation with PR depression Answer: D) Diffuse ST elevation with PR depression Rationale: Pericarditis commonly produces diffuse ST elevation and PR depression. Source basis: Emergency cardiology principles 17. An emergency nurse practitioner is reviewing Classic ECG pattern of acute pericarditis. Which statement is TRUE? A) Isolated Q waves B) Diffuse ST elevation with PR depression C) Short QT D) Territorial ST elevation only Answer: B) Diffuse ST elevation with PR depression Rationale: Pericarditis commonly produces diffuse ST elevation and PR depression. Source basis: Emergency cardiology principles 18. Which answer best describes the appropriate emergency-care principle for Classic ECG pattern of acute pericarditis? A) Isolated Q waves B) Short QT C) Diffuse ST elevation with PR depression D) Territorial ST elevation only Answer: C) Diffuse ST elevation with PR depression Rationale: Pericarditis commonly produces diffuse ST elevation and PR depression. Source basis: Emergency cardiology principles 19. Which of the following is correct regarding Irregularly irregular rhythm without consistent P waves? A) Complete heart block B) Sinus rhythm C) Atrial fibrillation D) Atrial paced rhythm Answer: C) Atrial fibrillation Rationale: AF produces chaotic atrial activity and an irregularly irregular ventricular response. Source basis: 2025 AHA Adult ALS 20. An emergency nurse practitioner is reviewing Irregularly irregular rhythm without consistent P waves. Which statement is TRUE? A) Sinus rhythm B) Atrial paced rhythm C) Atrial fibrillation D) Complete heart block Answer: C) Atrial fibrillation Rationale: AF produces chaotic atrial activity and an irregularly irregular ventricular response. Source basis: 2025 AHA Adult ALS 21. Which answer best describes the appropriate emergency-care principle for Irregularly irregular rhythm without consistentP waves? A) Complete heart block B) Sinus rhythm C) Atrial fibrillation D) Atrial paced rhythm Answer: C) Atrial fibrillation Rationale: AF produces chaotic atrial activity and an irregularly irregular ventricular response. Source basis: 2025 AHA Adult ALS 22. Which of the following is correct regarding Unstable tachyarrhythmia with hypotension? A) Synchronized cardioversion B) CT first C) Oral antibiotics D) Routine discharge Answer: A) Synchronized cardioversion Rationale: Hemodynamic instability from tachyarrhythmia requires immediate electrical therapy. Source basis: 2025 AHA Adult ALS 23. An emergency nurse practitioner is reviewing Unstable tachyarrhythmia with hypotension. Which statement is TRUE? A) Routine discharge B) Oral antibiotics C) CT first D) Synchronized cardioversion Answer: D) Synchronized cardioversion Rationale: Hemodynamic instability from tachyarrhythmia requires immediate electrical therapy. Source basis: 2025 AHA Adult ALS 24. Which answer best describes the appropriate emergency-care principle for Unstable tachyarrhythmia with hypotension? A) Routine discharge B) Synchronized cardioversion C) CT first D) Oral antibiotics Answer: B) Synchronized cardioversion Rationale: Hemodynamic instability from tachyarrhythmia requires immediate electrical therapy. Source basis: 2025 AHA Adult ALS 25. Which of the following is correct regarding Common medication for symptomatic bradycardia? A) Atropine B) Alteplase C) Warfarin D) Adenosine Answer: A) Atropine Rationale: Atropine is used for symptomatic bradycardia when appropriate. Source basis: 2025 AHA Adult ALS

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EMERGENCY NURSE PRACTITIONER (ENP)
400 Original Exam Questions & Answers




Emergency Nurse Practitioner (ENP) — 400 Original Practice Questions Page 1

, Cardiology
1. Which of the following is correct regarding ACS first-line antiplatelet?
A) Furosemide
B) Metformin
C) Warfarin
D) Aspirin
Answer: D) Aspirin
Rationale: Aspirin is foundational early antiplatelet therapy in ACS when not contraindicated.
Source basis: 2025 AHA/ACC/ACEP ACS Guideline

2. An emergency nurse practitioner is reviewing ACS first-line antiplatelet. Which statement is TRUE?
A) Metformin
B) Furosemide
C) Warfarin
D) Aspirin
Answer: D) Aspirin
Rationale: Aspirin is foundational early antiplatelet therapy in ACS when not contraindicated.
Source basis: 2025 AHA/ACC/ACEP ACS Guideline

3. Which answer best describes the appropriate emergency-care principle for ACS first-line antiplatelet?
A) Furosemide
B) Warfarin
C) Metformin
D) Aspirin
Answer: D) Aspirin
Rationale: Aspirin is foundational early antiplatelet therapy in ACS when not contraindicated.
Source basis: 2025 AHA/ACC/ACEP ACS Guideline

4. Which of the following is correct regarding STEMI reperfusion when timely PCI is available?
A) Stress testing first
B) Routine observation
C) Primary PCI
D) Oral antibiotics
Answer: C) Primary PCI
Rationale: Timely primary PCI is generally preferred when available.
Source basis: 2025 AHA/ACC/ACEP ACS Guideline

5. An emergency nurse practitioner is reviewing STEMI reperfusion when timely PCI is available. Which statement is
TRUE?
A) Oral antibiotics
B) Stress testing first
C) Routine observation
D) Primary PCI
Answer: D) Primary PCI
Rationale: Timely primary PCI is generally preferred when available.
Source basis: 2025 AHA/ACC/ACEP ACS Guideline

6. Which answer best describes the appropriate emergency-care principle for STEMI reperfusion when timely PCI
isavailable?
A) Routine observation
B) Primary PCI
C) Stress testing first
D) Oral antibiotics
Answer: B) Primary PCI
Rationale: Timely primary PCI is generally preferred when available.
Source basis: 2025 AHA/ACC/ACEP ACS Guideline

7. Which of the following is correct regarding Major nitrate contraindication in ACS?
A) Significant hypotension or recent PDE-5 inhibitor use
B) Normal heart rate
C) Age over 40
D) Mild nausea
Answer: A) Significant hypotension or recent PDE-5 inhibitor use
Rationale: Nitrates can cause dangerous hypotension in these settings.
Source basis: Emergency cardiovascular guidance




Emergency Nurse Practitioner (ENP) — 400 Original Practice Questions Page 2

, 8. An emergency nurse practitioner is reviewing Major nitrate contraindication in ACS. Which statement is TRUE?
A) Normal heart rate
B) Significant hypotension or recent PDE-5 inhibitor use
C) Mild nausea
D) Age over 40
Answer: B) Significant hypotension or recent PDE-5 inhibitor use
Rationale: Nitrates can cause dangerous hypotension in these settings.
Source basis: Emergency cardiovascular guidance

9. Which answer best describes the appropriate emergency-care principle for Major nitrate contraindication in ACS?
A) Mild nausea
B) Age over 40
C) Normal heart rate
D) Significant hypotension or recent PDE-5 inhibitor use
Answer: D) Significant hypotension or recent PDE-5 inhibitor use
Rationale: Nitrates can cause dangerous hypotension in these settings.
Source basis: Emergency cardiovascular guidance

10. Which of the following is correct regarding Inferior STEMI with hypotension and clear lungs?
A) GERD
B) Asthma
C) Right ventricular infarction
D) Migraine
Answer: C) Right ventricular infarction
Rationale: Inferior STEMI can involve the right ventricle and cause preload-dependent hypotension.
Source basis: Emergency cardiology principles

11. An emergency nurse practitioner is reviewing Inferior STEMI with hypotension and clear lungs. Which statement is
TRUE?
A) GERD
B) Right ventricular infarction
C) Asthma
D) Migraine
Answer: B) Right ventricular infarction
Rationale: Inferior STEMI can involve the right ventricle and cause preload-dependent hypotension.
Source basis: Emergency cardiology principles

12. Which answer best describes the appropriate emergency-care principle for Inferior STEMI with hypotension and
clearlungs?
A) GERD
B) Migraine
C) Right ventricular infarction
D) Asthma
Answer: C) Right ventricular infarction
Rationale: Inferior STEMI can involve the right ventricle and cause preload-dependent hypotension.
Source basis: Emergency cardiology principles

13. Which of the following is correct regarding Abrupt severe chest/back pain with pulse asymmetry suggests?
A) Pneumonia
B) GERD
C) Migraine
D) Aortic dissection
Answer: D) Aortic dissection
Rationale: Abrupt severe pain plus pulse/BP asymmetry is a classic warning pattern.
Source basis: ACEP thoracic aortic dissection policy

14. An emergency nurse practitioner is reviewing Abrupt severe chest/back pain with pulse asymmetry suggests.
Whichstatement is TRUE?
A) GERD
B) Migraine
C) Pneumonia
D) Aortic dissection
Answer: D) Aortic dissection
Rationale: Abrupt severe pain plus pulse/BP asymmetry is a classic warning pattern.
Source basis: ACEP thoracic aortic dissection policy




Emergency Nurse Practitioner (ENP) — 400 Original Practice Questions Page 3

, 15. Which answer best describes the appropriate emergency-care principle for Abrupt severe chest/back pain with
pulseasymmetry suggests?
A) GERD
B) Migraine
C) Aortic dissection
D) Pneumonia
Answer: C) Aortic dissection
Rationale: Abrupt severe pain plus pulse/BP asymmetry is a classic warning pattern.
Source basis: ACEP thoracic aortic dissection policy

16. Which of the following is correct regarding Classic ECG pattern of acute pericarditis?
A) Short QT
B) Isolated Q waves
C) Territorial ST elevation only
D) Diffuse ST elevation with PR depression
Answer: D) Diffuse ST elevation with PR depression
Rationale: Pericarditis commonly produces diffuse ST elevation and PR depression.
Source basis: Emergency cardiology principles

17. An emergency nurse practitioner is reviewing Classic ECG pattern of acute pericarditis. Which statement is TRUE?
A) Isolated Q waves
B) Diffuse ST elevation with PR depression
C) Short QT
D) Territorial ST elevation only
Answer: B) Diffuse ST elevation with PR depression
Rationale: Pericarditis commonly produces diffuse ST elevation and PR depression.
Source basis: Emergency cardiology principles

18. Which answer best describes the appropriate emergency-care principle for Classic ECG pattern of acute pericarditis?
A) Isolated Q waves
B) Short QT
C) Diffuse ST elevation with PR depression
D) Territorial ST elevation only
Answer: C) Diffuse ST elevation with PR depression
Rationale: Pericarditis commonly produces diffuse ST elevation and PR depression.
Source basis: Emergency cardiology principles

19. Which of the following is correct regarding Irregularly irregular rhythm without consistent P waves?
A) Complete heart block
B) Sinus rhythm
C) Atrial fibrillation
D) Atrial paced rhythm
Answer: C) Atrial fibrillation
Rationale: AF produces chaotic atrial activity and an irregularly irregular ventricular response.
Source basis: 2025 AHA Adult ALS

20. An emergency nurse practitioner is reviewing Irregularly irregular rhythm without consistent P waves. Which statement
is
TRUE?
A) Sinus rhythm
B) Atrial paced rhythm
C) Atrial fibrillation
D) Complete heart block
Answer: C) Atrial fibrillation
Rationale: AF produces chaotic atrial activity and an irregularly irregular ventricular response.
Source basis: 2025 AHA Adult ALS

21. Which answer best describes the appropriate emergency-care principle for Irregularly irregular rhythm without
consistentP waves?
A) Complete heart block
B) Sinus rhythm
C) Atrial fibrillation
D) Atrial paced rhythm
Answer: C) Atrial fibrillation
Rationale: AF produces chaotic atrial activity and an irregularly irregular ventricular response.
Source basis: 2025 AHA Adult ALS




Emergency Nurse Practitioner (ENP) — 400 Original Practice Questions Page 4

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