ABSITE COMPREHENSIVE EXAM STUDY
GUIDE COMPLETE QUESTIONS AND
SOLUTIONS
●● What is the blood supply to the body and tail of the pancreas
Answer: branches of the splenic artery
Head and uncinate process receive supply through arcades from the
hepatic and GDA
●● Pseudocyst CEA and Amylase
Answer: Amylase high
CEA low < 200
●● Serous cystadenoma CEA and Amylase
Answer: Both low
●● Mucinous cystic neoplasm amylase and CEA
Answer: Amylase low
CEA High >200
●● IPMN CEA and Amylase
,Answer: Amylase high
CEA High > 200
●● Ranson Criteria at admission and at 48 hrs
Answer: At admission
Age > 55
WBC >16
Glucose>200
LDH > 350
AST > 250
At 48hr
Hematocrit decrease >10%
BUN increase > 5
Base deficit >4
Fluid requirement > 6L
PaO2 <60
Calcium < 8
●● Glucagonoma
Answer: Sx/signs: DVT, necrolytic migratory erythema, weight loss,
DM, anemia, stomatitis
, Glucagon is produced by alpha cells
Most commonly found in the body and tail of the pancreas
Typically tx w/ distal pancreatectomy with splenectomy
●● What clinical scenario is consistent with watery diarrhea,
hypokalemia, and achlorhydria
Answer: VIPoma
Most often in distal pancreas
●● What scenario is steatorrhea, DM and cholelithiasis
Answer: Somatostatinoma
●● Tx option for a metastatic, somatostatin receptor negative
neuroendocrine tumor
Answer: Everolimus
Improves progression feee survival for patients with well differentiated
metastatic pancreatic neuroendocrine tumors
●● What genetic abnormality plays a role in pancreatic cancer
Answer: KRAS
GUIDE COMPLETE QUESTIONS AND
SOLUTIONS
●● What is the blood supply to the body and tail of the pancreas
Answer: branches of the splenic artery
Head and uncinate process receive supply through arcades from the
hepatic and GDA
●● Pseudocyst CEA and Amylase
Answer: Amylase high
CEA low < 200
●● Serous cystadenoma CEA and Amylase
Answer: Both low
●● Mucinous cystic neoplasm amylase and CEA
Answer: Amylase low
CEA High >200
●● IPMN CEA and Amylase
,Answer: Amylase high
CEA High > 200
●● Ranson Criteria at admission and at 48 hrs
Answer: At admission
Age > 55
WBC >16
Glucose>200
LDH > 350
AST > 250
At 48hr
Hematocrit decrease >10%
BUN increase > 5
Base deficit >4
Fluid requirement > 6L
PaO2 <60
Calcium < 8
●● Glucagonoma
Answer: Sx/signs: DVT, necrolytic migratory erythema, weight loss,
DM, anemia, stomatitis
, Glucagon is produced by alpha cells
Most commonly found in the body and tail of the pancreas
Typically tx w/ distal pancreatectomy with splenectomy
●● What clinical scenario is consistent with watery diarrhea,
hypokalemia, and achlorhydria
Answer: VIPoma
Most often in distal pancreas
●● What scenario is steatorrhea, DM and cholelithiasis
Answer: Somatostatinoma
●● Tx option for a metastatic, somatostatin receptor negative
neuroendocrine tumor
Answer: Everolimus
Improves progression feee survival for patients with well differentiated
metastatic pancreatic neuroendocrine tumors
●● What genetic abnormality plays a role in pancreatic cancer
Answer: KRAS
