NRSG 2350 EXAM 3 STUDY GUIDE 2026 300 Practice Questions with Verified Answers &
Detailed Rationales | All Core Domains Covered | A+ Graded
Table of Contents
Exam Overview ...... 3
Domain 1: Cardiovascular Disorders (Questions 1–50) ...... 4
Domain 2: Respiratory Disorders (Questions 51–100) ...... 9
Domain 3: Endocrine Disorders (Questions 101–150) ...... 14
Domain 4: Fluid, Electrolyte & Acid-Base Balance (Questions 151–190) ...... 19
Domain 5: Renal & Urinary Disorders (Questions 191–230) ...... 23
Domain 6: Gastrointestinal & Hepatic Disorders (Questions 231–260) ...... 27
Domain 7: Leadership, Delegation & Prioritization (Questions 261–280) ...... 30
Domain 8: Clinical Scenarios & Prioritization (Questions 281–300) ...... 32
Answer Key ...... 35
---
,Exam Overview
The NRSG 2350 EXAM 3 STUDY GUIDE is designed to assist nursing students in preparing for the
third major examination in their medical-surgical nursing course. This comprehensive study
guide covers key content areas including cardiovascular, respiratory, endocrine, renal,
gastrointestinal, and leadership concepts essential for success on the exam and in clinical
practice.
| Exam Detail | Information |
|-------------|-------------|
| Course | NRSG 2350: Medical-Surgical Nursing |
| Exam Focus | Cardiovascular, respiratory, endocrine, renal, GI, leadership, and prioritization |
| Format | Multiple-choice, select-all-that-apply, clinical scenarios, prioritization questions |
| Key Topics | Heart failure, MI, COPD, asthma, diabetes, thyroid disorders, fluid/electrolyte
imbalances, kidney disorders, liver disease, delegation, prioritization |
Core Competencies Assessed:
- Cardiovascular Disorders — Heart failure, myocardial infarction, hypertension, valvular
disorders, arrhythmias
- Respiratory Disorders — COPD, asthma, pneumonia, pulmonary embolism, TB, ARDS
- Endocrine Disorders — Diabetes mellitus, thyroid disorders, adrenal insufficiency, Cushing's
syndrome
- Fluid, Electrolyte & Acid-Base — Imbalances, IV therapy, ABG interpretation
- Renal & Urinary Disorders — AKI, CKD, dialysis, UTI, nephrolithiasis
- Gastrointestinal & Hepatic — GI bleeding, cirrhosis, hepatitis, pancreatitis, IBD
- Leadership, Delegation & Prioritization — NCLEX-style prioritization, delegation, and clinical
judgment questions
,---
Domain 1: Cardiovascular Disorders (Questions 1–50)
---
Q1. A client with heart failure has crackles in the lung bases and peripheral edema. Which of the
following is the most appropriate medication to reduce fluid volume?
A) Beta-blocker
B) ACE inhibitor
C) Loop diuretic
D) Digoxin
Answer: C
Rationale: Loop diuretics (e.g., furosemide) reduce fluid volume by promoting diuresis, relieving
symptoms of fluid overload. Beta-blockers and ACE inhibitors are used for chronic management
but do not directly reduce fluid volume.
---
Q2. A client with heart failure is prescribed digoxin. Which of the following is a sign of digoxin
toxicity?
A) Tachycardia
, B) Visual disturbances (yellow-green halos)
C) Weight gain
D) Hypotension
Answer: B
Rationale: Digoxin toxicity can cause visual disturbances (yellow-green halos), nausea, vomiting,
bradycardia, and cardiac arrhythmias. Serum digoxin levels should be monitored.
---
Q3. A client with heart failure has an S3 gallop. This indicates:
A) Volume overload
B) Stiff ventricle
C) Valve stenosis
D) Normal finding
Answer: A
Rationale: An S3 heart sound reflects increased filling pressures and volume overload,
commonly seen in heart failure.
---
Q4. A client with heart failure and an ejection fraction of 25% is on lisinopril, carvedilol, and
furosemide. Which medication should be added to reduce mortality?
Detailed Rationales | All Core Domains Covered | A+ Graded
Table of Contents
Exam Overview ...... 3
Domain 1: Cardiovascular Disorders (Questions 1–50) ...... 4
Domain 2: Respiratory Disorders (Questions 51–100) ...... 9
Domain 3: Endocrine Disorders (Questions 101–150) ...... 14
Domain 4: Fluid, Electrolyte & Acid-Base Balance (Questions 151–190) ...... 19
Domain 5: Renal & Urinary Disorders (Questions 191–230) ...... 23
Domain 6: Gastrointestinal & Hepatic Disorders (Questions 231–260) ...... 27
Domain 7: Leadership, Delegation & Prioritization (Questions 261–280) ...... 30
Domain 8: Clinical Scenarios & Prioritization (Questions 281–300) ...... 32
Answer Key ...... 35
---
,Exam Overview
The NRSG 2350 EXAM 3 STUDY GUIDE is designed to assist nursing students in preparing for the
third major examination in their medical-surgical nursing course. This comprehensive study
guide covers key content areas including cardiovascular, respiratory, endocrine, renal,
gastrointestinal, and leadership concepts essential for success on the exam and in clinical
practice.
| Exam Detail | Information |
|-------------|-------------|
| Course | NRSG 2350: Medical-Surgical Nursing |
| Exam Focus | Cardiovascular, respiratory, endocrine, renal, GI, leadership, and prioritization |
| Format | Multiple-choice, select-all-that-apply, clinical scenarios, prioritization questions |
| Key Topics | Heart failure, MI, COPD, asthma, diabetes, thyroid disorders, fluid/electrolyte
imbalances, kidney disorders, liver disease, delegation, prioritization |
Core Competencies Assessed:
- Cardiovascular Disorders — Heart failure, myocardial infarction, hypertension, valvular
disorders, arrhythmias
- Respiratory Disorders — COPD, asthma, pneumonia, pulmonary embolism, TB, ARDS
- Endocrine Disorders — Diabetes mellitus, thyroid disorders, adrenal insufficiency, Cushing's
syndrome
- Fluid, Electrolyte & Acid-Base — Imbalances, IV therapy, ABG interpretation
- Renal & Urinary Disorders — AKI, CKD, dialysis, UTI, nephrolithiasis
- Gastrointestinal & Hepatic — GI bleeding, cirrhosis, hepatitis, pancreatitis, IBD
- Leadership, Delegation & Prioritization — NCLEX-style prioritization, delegation, and clinical
judgment questions
,---
Domain 1: Cardiovascular Disorders (Questions 1–50)
---
Q1. A client with heart failure has crackles in the lung bases and peripheral edema. Which of the
following is the most appropriate medication to reduce fluid volume?
A) Beta-blocker
B) ACE inhibitor
C) Loop diuretic
D) Digoxin
Answer: C
Rationale: Loop diuretics (e.g., furosemide) reduce fluid volume by promoting diuresis, relieving
symptoms of fluid overload. Beta-blockers and ACE inhibitors are used for chronic management
but do not directly reduce fluid volume.
---
Q2. A client with heart failure is prescribed digoxin. Which of the following is a sign of digoxin
toxicity?
A) Tachycardia
, B) Visual disturbances (yellow-green halos)
C) Weight gain
D) Hypotension
Answer: B
Rationale: Digoxin toxicity can cause visual disturbances (yellow-green halos), nausea, vomiting,
bradycardia, and cardiac arrhythmias. Serum digoxin levels should be monitored.
---
Q3. A client with heart failure has an S3 gallop. This indicates:
A) Volume overload
B) Stiff ventricle
C) Valve stenosis
D) Normal finding
Answer: A
Rationale: An S3 heart sound reflects increased filling pressures and volume overload,
commonly seen in heart failure.
---
Q4. A client with heart failure and an ejection fraction of 25% is on lisinopril, carvedilol, and
furosemide. Which medication should be added to reduce mortality?
