ATI RN Pharmacology Exam 2026
with Next Generation NCLEX (NGN) Format
Total Questions: 70 Multiple Choice Questions
Format: Standard MCQ, Select All That Apply, Ordered Response
Content Areas: Cardiovascular, Respiratory, Endocrine, GI, Neurological, Psychiatric,
Pain Management,
Includes: Answer Key with Detailed Rationales
Instructions: Read each question carefully. For standard multiple-choice questions, select the single best answer. For
"Select All That Apply" questions, select all answers that apply. For "Ordered Response" questions, place the steps in
the correct sequence. Choose the best answer based on your nursing knowledge and pharmacological principles.
,ATI RN Pharmacology Exam with NGN 70 Questions
Section 1: Examination Questions
Answer key at the end
[Multiple Choice]
A nurse is caring for a client with heart failure who has been prescribed digoxin
(Lanoxin). The client's serum digoxin level is 2.4 ng/mL. The nurse assesses the
client and notes nausea, vomiting, and visual disturbances including yellow-green
halos around lights.
1. Which of the following actions should the nurse take first?
A. Administer the next scheduled dose of digoxin
B. Withhold the digoxin and notify the health care provider
C. Check the client's potassium level and administer potassium supplements
D. Encourage the client to eat foods rich in potassium
[Multiple Choice]
A client with atrial fibrillation is started on warfarin (Coumadin) therapy. The
nurse is providing discharge teaching about dietary considerations.
2. Which statement by the client indicates an understanding of the teaching?
A. "I should eat more green leafy vegetables while taking this medication."
B. "I should avoid foods that contain vitamin K, such as broccoli and spinach."
C. "I should maintain a consistent intake of vitamin K-containing foods in my diet."
D. "I should take a vitamin K supplement daily to prevent bleeding."
[Select All That Apply]
A nurse is preparing to administer lisinopril (Prinivil) to a client with hypertension.
Before giving the medication, the nurse reviews the client's assessment findings.
3. Which ofthe following findings should the nurse report to the health
care provider before administering the medication? (Select all that
apply.)
A. Blood pressure of 90/60 mmHg
B. Serum potassium level of 5.8 mEq/L
2
,ATI RN Pharmacology Exam with NGN 70 Questions
C. Heart rate of 78 bpm
D. Dry, nonproductive cough
E. Serum creatinine of 3.2 mg/dL
F. Client reports occasional headache
[Multiple Choice]
A client with hypertension is prescribed metoprolol (Lopressor), a beta-blocker.
The nurse is reviewing the client's medication history.
4.The nurse should identify that which of the following conditions is a
contraindication for beta-blocker therapy?
A. Diabetes mellitus type 2
3
, ATI RN Pharmacology Exam with NGN 70 Questions
B. Asthma
C. Osteoarthritis
D. Benign prostatic hyperplasia
[Multiple Choice]
A nurse is caring for a client receiving heparin by continuous IV infusion for
treatment of a deep vein thrombosis. The activated partial thromboplastin time
(aPTT) is 110 seconds, and the control aPTT is 30 seconds.
5. Based on this result, what action should the nurse take?
A. Continue the current infusion rate
B. Increase the heparin infusion rate
C. Stop the heparin infusion and prepare to administer protamine sulfate
D. Decrease the heparin infusion rate by 50%
[Multiple Choice]
A nurse is providing discharge instructions to a client who has a new prescription
for sublingual nitroglycerin (Nitrostat) for angina pectoris.
6. Which of the following instructions should the nurse include?
A. "Take one tablet every 5 minutes for up to three doses for chest pain."
B. "Store the tablets in the bathroom medicine cabinet for easy access."
C. "Take the medication with a full glass of water to enhance absorption."
D. "Replace the medication every 12 months regardless of use."
[Multiple Choice]
A client with heart failure is prescribed furosemide (Lasix) 40 mg IV push. The
nurse reviews the client's most recent laboratory values.
7. Which laboratory finding is most important for the nurse to check
before administering the furosemide?
A. Serum sodium of 138 mEq/L
B. Serum potassium of 3.0 mEq/L
C. Serum chloride of 100 mEq/L
4
with Next Generation NCLEX (NGN) Format
Total Questions: 70 Multiple Choice Questions
Format: Standard MCQ, Select All That Apply, Ordered Response
Content Areas: Cardiovascular, Respiratory, Endocrine, GI, Neurological, Psychiatric,
Pain Management,
Includes: Answer Key with Detailed Rationales
Instructions: Read each question carefully. For standard multiple-choice questions, select the single best answer. For
"Select All That Apply" questions, select all answers that apply. For "Ordered Response" questions, place the steps in
the correct sequence. Choose the best answer based on your nursing knowledge and pharmacological principles.
,ATI RN Pharmacology Exam with NGN 70 Questions
Section 1: Examination Questions
Answer key at the end
[Multiple Choice]
A nurse is caring for a client with heart failure who has been prescribed digoxin
(Lanoxin). The client's serum digoxin level is 2.4 ng/mL. The nurse assesses the
client and notes nausea, vomiting, and visual disturbances including yellow-green
halos around lights.
1. Which of the following actions should the nurse take first?
A. Administer the next scheduled dose of digoxin
B. Withhold the digoxin and notify the health care provider
C. Check the client's potassium level and administer potassium supplements
D. Encourage the client to eat foods rich in potassium
[Multiple Choice]
A client with atrial fibrillation is started on warfarin (Coumadin) therapy. The
nurse is providing discharge teaching about dietary considerations.
2. Which statement by the client indicates an understanding of the teaching?
A. "I should eat more green leafy vegetables while taking this medication."
B. "I should avoid foods that contain vitamin K, such as broccoli and spinach."
C. "I should maintain a consistent intake of vitamin K-containing foods in my diet."
D. "I should take a vitamin K supplement daily to prevent bleeding."
[Select All That Apply]
A nurse is preparing to administer lisinopril (Prinivil) to a client with hypertension.
Before giving the medication, the nurse reviews the client's assessment findings.
3. Which ofthe following findings should the nurse report to the health
care provider before administering the medication? (Select all that
apply.)
A. Blood pressure of 90/60 mmHg
B. Serum potassium level of 5.8 mEq/L
2
,ATI RN Pharmacology Exam with NGN 70 Questions
C. Heart rate of 78 bpm
D. Dry, nonproductive cough
E. Serum creatinine of 3.2 mg/dL
F. Client reports occasional headache
[Multiple Choice]
A client with hypertension is prescribed metoprolol (Lopressor), a beta-blocker.
The nurse is reviewing the client's medication history.
4.The nurse should identify that which of the following conditions is a
contraindication for beta-blocker therapy?
A. Diabetes mellitus type 2
3
, ATI RN Pharmacology Exam with NGN 70 Questions
B. Asthma
C. Osteoarthritis
D. Benign prostatic hyperplasia
[Multiple Choice]
A nurse is caring for a client receiving heparin by continuous IV infusion for
treatment of a deep vein thrombosis. The activated partial thromboplastin time
(aPTT) is 110 seconds, and the control aPTT is 30 seconds.
5. Based on this result, what action should the nurse take?
A. Continue the current infusion rate
B. Increase the heparin infusion rate
C. Stop the heparin infusion and prepare to administer protamine sulfate
D. Decrease the heparin infusion rate by 50%
[Multiple Choice]
A nurse is providing discharge instructions to a client who has a new prescription
for sublingual nitroglycerin (Nitrostat) for angina pectoris.
6. Which of the following instructions should the nurse include?
A. "Take one tablet every 5 minutes for up to three doses for chest pain."
B. "Store the tablets in the bathroom medicine cabinet for easy access."
C. "Take the medication with a full glass of water to enhance absorption."
D. "Replace the medication every 12 months regardless of use."
[Multiple Choice]
A client with heart failure is prescribed furosemide (Lasix) 40 mg IV push. The
nurse reviews the client's most recent laboratory values.
7. Which laboratory finding is most important for the nurse to check
before administering the furosemide?
A. Serum sodium of 138 mEq/L
B. Serum potassium of 3.0 mEq/L
C. Serum chloride of 100 mEq/L
4