TEST BANK FOR JANEWAY'S IMMUNOBIOLOGY,
11TH EDITION AUTHORS: KENNETH M. MURPHY, CASEY WEAVER
COMPREHENSIVE EXAM BANK 300 REAL EXAM QUESTIONS &
ANSWERS WITH DETAILED RATIONALES 100% VERIFIED | GRADED A+
| 2026/2027 UPDATED
SECTION 1: BASIC CONCEPTS IN IMMUNOLOGY
QUESTION 1
The response of antigen-specific lymphocytes to antigen, including the
development of immunological memory, is known as:
A. Innate immune response
B. Acquired immune response
C. Inflammatory response
D. Immunological tolerance
ANSWER: B
RATIONALE: The acquired (adaptive) immune response involves antigen-specific
lymphocytes and results in the development of immunological memory, providing
long-lasting protection. This is distinct from the innate immune response,
which is immediate and non-specific.
QUESTION 2
Which of the following is a hallmark of the adaptive immune system?
A. Response to a broad range of pathogens
B. Immediate, non-specific defense mechanisms
C. Specificity and memory
D. Reliance on physical barriers
ANSWER: C
RATIONALE: The adaptive immune system is characterized by its specificity for
particular antigens and its ability to "remember" past encounters, leading to
a stronger and faster response upon re-exposure.
1
,QUESTION 3
The general term for the ability of cells of the innate and adaptive immune
system to recognize the presence of an infection is:
A. Inflammation
B. Immunological recognition
C. Immunological memory
D. Clonal selection
ANSWER: B
RATIONALE: Immunological recognition is the broad term for how the immune
system senses infection, encompassing the innate system's ability to recognize
broad pathogen-associated patterns and the adaptive system's recognition of
specific antigens.
QUESTION 4
The study of all aspects of host defense against infection, including the
adverse consequences of immune responses, is called:
A. Pathology
B. Immunology
C. Microbiology
D. Serology
ANSWER: B
RATIONALE: Immunology is the field of study that covers all aspects of host
defense against pathogens, as well as the pathological consequences of immune
responses (such as autoimmunity and allergy).
QUESTION 5
The general term for the local accumulation of fluid, plasma proteins, and
white blood cells that is initiated by physical injury or infection is:
A. Edema
B. Inflammation
C. Immunization
2
,D. Phagocytosis
ANSWER: B
RATIONALE: Inflammation is the hallmark response to tissue damage or infection,
characterized by the local accumulation of fluid, plasma proteins, and
leukocytes. This response is initiated by inflammatory inducers and is a key
component of both innate and adaptive immunity.
QUESTION 6
Cells that invade inflamed tissues, such as macrophages, neutrophils, and
effector T cells, are collectively called:
A. Inflammatory cells
B. Plasma cells
C. Antigen-presenting cells
D. Memory cells
ANSWER: A
RATIONALE: Inflammatory cells are the leukocytes (white blood cells) that are
recruited to sites of infection or injury and contribute to the inflammatory
process.
QUESTION 7
The portion of a response to infection that is due to the body's relatively
non-specific defense mechanisms, which are activated immediately, is the:
A. Adaptive immune response
B. Inflammatory response
C. Innate immune response
D. Humoral immune response
ANSWER: C
RATIONALE: The innate immune response is the first line of defense and relies
on non-specific mechanisms that are present from birth. It acts quickly to
contain infections and does not involve antigen-specific lymphocytes.
3
, QUESTION 8
A white blood cell is known as a:
A. Lymphocyte
B. Leukocyte
C. Monocyte
D. Macrophage
ANSWER: B
RATIONALE: The general term for a white blood cell is a leukocyte. This
category includes various cell types, such as lymphocytes, polymorphonuclear
leukocytes (granulocytes), and monocytes.
QUESTION 9
The fluid that accumulates in tissues and is drained by the lymphatic system
is called:
A. Blood plasma
B. Lymph
C. Cerebrospinal fluid
D. Interstitial fluid
ANSWER: B
RATIONALE: Lymph is the extracellular fluid that bathes tissues and is
collected by lymphatic vessels and returned to the blood via the thoracic
duct.
QUESTION 10
Thin-walled vessels that carry lymph throughout the body are known as:
A. Lymph nodes
B. Lymphatic vessels
C. Blood capillaries
D. Venules
4
11TH EDITION AUTHORS: KENNETH M. MURPHY, CASEY WEAVER
COMPREHENSIVE EXAM BANK 300 REAL EXAM QUESTIONS &
ANSWERS WITH DETAILED RATIONALES 100% VERIFIED | GRADED A+
| 2026/2027 UPDATED
SECTION 1: BASIC CONCEPTS IN IMMUNOLOGY
QUESTION 1
The response of antigen-specific lymphocytes to antigen, including the
development of immunological memory, is known as:
A. Innate immune response
B. Acquired immune response
C. Inflammatory response
D. Immunological tolerance
ANSWER: B
RATIONALE: The acquired (adaptive) immune response involves antigen-specific
lymphocytes and results in the development of immunological memory, providing
long-lasting protection. This is distinct from the innate immune response,
which is immediate and non-specific.
QUESTION 2
Which of the following is a hallmark of the adaptive immune system?
A. Response to a broad range of pathogens
B. Immediate, non-specific defense mechanisms
C. Specificity and memory
D. Reliance on physical barriers
ANSWER: C
RATIONALE: The adaptive immune system is characterized by its specificity for
particular antigens and its ability to "remember" past encounters, leading to
a stronger and faster response upon re-exposure.
1
,QUESTION 3
The general term for the ability of cells of the innate and adaptive immune
system to recognize the presence of an infection is:
A. Inflammation
B. Immunological recognition
C. Immunological memory
D. Clonal selection
ANSWER: B
RATIONALE: Immunological recognition is the broad term for how the immune
system senses infection, encompassing the innate system's ability to recognize
broad pathogen-associated patterns and the adaptive system's recognition of
specific antigens.
QUESTION 4
The study of all aspects of host defense against infection, including the
adverse consequences of immune responses, is called:
A. Pathology
B. Immunology
C. Microbiology
D. Serology
ANSWER: B
RATIONALE: Immunology is the field of study that covers all aspects of host
defense against pathogens, as well as the pathological consequences of immune
responses (such as autoimmunity and allergy).
QUESTION 5
The general term for the local accumulation of fluid, plasma proteins, and
white blood cells that is initiated by physical injury or infection is:
A. Edema
B. Inflammation
C. Immunization
2
,D. Phagocytosis
ANSWER: B
RATIONALE: Inflammation is the hallmark response to tissue damage or infection,
characterized by the local accumulation of fluid, plasma proteins, and
leukocytes. This response is initiated by inflammatory inducers and is a key
component of both innate and adaptive immunity.
QUESTION 6
Cells that invade inflamed tissues, such as macrophages, neutrophils, and
effector T cells, are collectively called:
A. Inflammatory cells
B. Plasma cells
C. Antigen-presenting cells
D. Memory cells
ANSWER: A
RATIONALE: Inflammatory cells are the leukocytes (white blood cells) that are
recruited to sites of infection or injury and contribute to the inflammatory
process.
QUESTION 7
The portion of a response to infection that is due to the body's relatively
non-specific defense mechanisms, which are activated immediately, is the:
A. Adaptive immune response
B. Inflammatory response
C. Innate immune response
D. Humoral immune response
ANSWER: C
RATIONALE: The innate immune response is the first line of defense and relies
on non-specific mechanisms that are present from birth. It acts quickly to
contain infections and does not involve antigen-specific lymphocytes.
3
, QUESTION 8
A white blood cell is known as a:
A. Lymphocyte
B. Leukocyte
C. Monocyte
D. Macrophage
ANSWER: B
RATIONALE: The general term for a white blood cell is a leukocyte. This
category includes various cell types, such as lymphocytes, polymorphonuclear
leukocytes (granulocytes), and monocytes.
QUESTION 9
The fluid that accumulates in tissues and is drained by the lymphatic system
is called:
A. Blood plasma
B. Lymph
C. Cerebrospinal fluid
D. Interstitial fluid
ANSWER: B
RATIONALE: Lymph is the extracellular fluid that bathes tissues and is
collected by lymphatic vessels and returned to the blood via the thoracic
duct.
QUESTION 10
Thin-walled vessels that carry lymph throughout the body are known as:
A. Lymph nodes
B. Lymphatic vessels
C. Blood capillaries
D. Venules
4
