TEST BANK FOR PATHOPHYSIOLOGY
THE BIOLOGIC BASIS FOR DISEASE IN
ADULTS AND CHILDREN 8 TH EDITION
BY KATHRYN L. MCCANCE
CERTIFICATION SCRIPT 2026
QUESTIONS WITH SOLUTIONS
GRADED A+
◍ Lead's biological effects.
Answer: Interferes with various biological activities at the cellular and
molecular levels.
◍ Adrenergic agents effect on K+.
Answer: albuterol, beta blockers, and alpha adrenergic antagonists cause K+
movement into the cell. Alpha adrenergic receptors shift K+ out of the cell
◍ Endoplasmic reticulum.
Answer: A membrane factory that specializes in the synthesis and transport
of the protein and lipid components of most of the cell's organelles.
◍ neuroglia.
Answer: most numerous type of CNS cell
◍ Diffusion.
Answer: Passive solute movement from high to low concentration.
◍ spinal cord.
Answer: conducts somatic and autonomic reflexes, provides motor pattern
control centers, and serves as a sensory and motor modulation center
,◍ Congenital Adrenal Hyperplasia.
Answer: Genetic disorder affecting adrenal hormone production.
◍ IgG.
Answer: The antibody class that mediates passive immunity obtained from
pregnant parent to the fetus.
◍ RNA polymerase.
Answer: Enzyme that transcribes DNA into RNA
◍ Fever as a symptom.
Answer: An example of a systemic manifestation of influenza.
◍ Define systemic.
Answer: Systemic means affecting the entire body, rather than a single
organ or body part.Ex: High blood pressure
◍ convergence.
Answer: branches of numerous neurons converging on and influencing one
or a few nuerons
◍ Complete Trisomy of the Twenty-First Chromosome.
Answer: A condition where individuals exhibit an IQ of 25 to 70, a low
nasal bridge, protruding tongue, and flat, low-set ears.
◍ Facial anomalies.
Answer: Another potential effect of fetal alcohol syndrome on newborns.
◍ Gene Fragment.
Answer: Specific DNA sequence responsible for protein production.
◍ Hemosiderin.
Answer: Causes color changes in bruises like black eye.
◍ Kidney Function Tests.
Answer: Assessments to evaluate renal health and function.
◍ Paracrine signaling.
Answer: A mode of chemical signaling where local chemical mediators are
, quickly taken up, destroyed, or immobilized.
◍ Renal Compensation.
Answer: Kidneys adjust bicarbonate levels in response.
◍ The manifestations of a disease are best defined as the:
A. Subjective feelings of discomfort during a chronic illness
B. Signs and symptoms of a disease
C. Factors that precipitate an acute episode of a chronic illness
D. Early indicators of the prodromal stage of infection.
Answer: B. Signs and symptoms of a disease
◍ Dietary restriction.
Answer: Necessary for managing hemochromatosis to prevent damage.
◍ Mitosis.
Answer: All types of cells undergo mitosis during the formation of the
embryo.
◍ Action Potential.
Answer: Rapid change in membrane potential for nerve signal.
◍ A change in a tissue marked by cells that vary in size and shape and show
increased meiotic figures would be called:
A. Metaplasia
B. Atrophy
C. Dysplasia
D. Hypertrophy.
Answer: C. Dysplasia
◍ Atony.
Answer: Lack of normal muscle tone or tension; flaccidity.
◍ Benign neoplastic tumor.
Answer: Well-differentiated, slow-growing, and localized.
◍ Deep tissue fungal infections.
Answer: Found almost exclusively in immunocompromised clients.
, ◍ Specific immunity.
Answer: Targeted response to particular antigens.
◍ True statement about eukaryotic cells.
Answer: They contain compartments called organelles.
◍ Type III hypersensitivity reaction.
Answer: Systemic lupus erythematosus (SLE) is an example of this type of
hypersensitivity reaction.
◍ uses for tumor markers.
Answer: used to screen & identify individuals at high risk for ca- help
diagnose specific types of tumors- follow clinical course of ca
◍ Autocrine Signaling.
Answer: Cell affects its own activity through released chemicals.
◍ dawn phenomenon.
Answer: type I DM has higher blood glucose in early am than in middle of
night
◍ All of the following are part of the Seven Steps to Health EXCEPT: A)
follow cancer screening guidelines.B) use sun block agents whenever
exposed.C) participate in strenuous exercise on a regular daily basis.D)
choose high fiber, lower fat foods..
Answer: C
◍ Hydrostatic pressure.
Answer: Force of fluid against a cell membrane.
◍ Recombinant DNA Technology.
Answer: Method to isolate and reproduce specific gene fragments.
◍ Hyperphosphatemia.
Answer: Increased phosphate from long-term use of phosphate containing
enemas or laxatives, hypoparathyroidism
◍ Water tends to move together with which electrolyte?a) Magnesiumb)
THE BIOLOGIC BASIS FOR DISEASE IN
ADULTS AND CHILDREN 8 TH EDITION
BY KATHRYN L. MCCANCE
CERTIFICATION SCRIPT 2026
QUESTIONS WITH SOLUTIONS
GRADED A+
◍ Lead's biological effects.
Answer: Interferes with various biological activities at the cellular and
molecular levels.
◍ Adrenergic agents effect on K+.
Answer: albuterol, beta blockers, and alpha adrenergic antagonists cause K+
movement into the cell. Alpha adrenergic receptors shift K+ out of the cell
◍ Endoplasmic reticulum.
Answer: A membrane factory that specializes in the synthesis and transport
of the protein and lipid components of most of the cell's organelles.
◍ neuroglia.
Answer: most numerous type of CNS cell
◍ Diffusion.
Answer: Passive solute movement from high to low concentration.
◍ spinal cord.
Answer: conducts somatic and autonomic reflexes, provides motor pattern
control centers, and serves as a sensory and motor modulation center
,◍ Congenital Adrenal Hyperplasia.
Answer: Genetic disorder affecting adrenal hormone production.
◍ IgG.
Answer: The antibody class that mediates passive immunity obtained from
pregnant parent to the fetus.
◍ RNA polymerase.
Answer: Enzyme that transcribes DNA into RNA
◍ Fever as a symptom.
Answer: An example of a systemic manifestation of influenza.
◍ Define systemic.
Answer: Systemic means affecting the entire body, rather than a single
organ or body part.Ex: High blood pressure
◍ convergence.
Answer: branches of numerous neurons converging on and influencing one
or a few nuerons
◍ Complete Trisomy of the Twenty-First Chromosome.
Answer: A condition where individuals exhibit an IQ of 25 to 70, a low
nasal bridge, protruding tongue, and flat, low-set ears.
◍ Facial anomalies.
Answer: Another potential effect of fetal alcohol syndrome on newborns.
◍ Gene Fragment.
Answer: Specific DNA sequence responsible for protein production.
◍ Hemosiderin.
Answer: Causes color changes in bruises like black eye.
◍ Kidney Function Tests.
Answer: Assessments to evaluate renal health and function.
◍ Paracrine signaling.
Answer: A mode of chemical signaling where local chemical mediators are
, quickly taken up, destroyed, or immobilized.
◍ Renal Compensation.
Answer: Kidneys adjust bicarbonate levels in response.
◍ The manifestations of a disease are best defined as the:
A. Subjective feelings of discomfort during a chronic illness
B. Signs and symptoms of a disease
C. Factors that precipitate an acute episode of a chronic illness
D. Early indicators of the prodromal stage of infection.
Answer: B. Signs and symptoms of a disease
◍ Dietary restriction.
Answer: Necessary for managing hemochromatosis to prevent damage.
◍ Mitosis.
Answer: All types of cells undergo mitosis during the formation of the
embryo.
◍ Action Potential.
Answer: Rapid change in membrane potential for nerve signal.
◍ A change in a tissue marked by cells that vary in size and shape and show
increased meiotic figures would be called:
A. Metaplasia
B. Atrophy
C. Dysplasia
D. Hypertrophy.
Answer: C. Dysplasia
◍ Atony.
Answer: Lack of normal muscle tone or tension; flaccidity.
◍ Benign neoplastic tumor.
Answer: Well-differentiated, slow-growing, and localized.
◍ Deep tissue fungal infections.
Answer: Found almost exclusively in immunocompromised clients.
, ◍ Specific immunity.
Answer: Targeted response to particular antigens.
◍ True statement about eukaryotic cells.
Answer: They contain compartments called organelles.
◍ Type III hypersensitivity reaction.
Answer: Systemic lupus erythematosus (SLE) is an example of this type of
hypersensitivity reaction.
◍ uses for tumor markers.
Answer: used to screen & identify individuals at high risk for ca- help
diagnose specific types of tumors- follow clinical course of ca
◍ Autocrine Signaling.
Answer: Cell affects its own activity through released chemicals.
◍ dawn phenomenon.
Answer: type I DM has higher blood glucose in early am than in middle of
night
◍ All of the following are part of the Seven Steps to Health EXCEPT: A)
follow cancer screening guidelines.B) use sun block agents whenever
exposed.C) participate in strenuous exercise on a regular daily basis.D)
choose high fiber, lower fat foods..
Answer: C
◍ Hydrostatic pressure.
Answer: Force of fluid against a cell membrane.
◍ Recombinant DNA Technology.
Answer: Method to isolate and reproduce specific gene fragments.
◍ Hyperphosphatemia.
Answer: Increased phosphate from long-term use of phosphate containing
enemas or laxatives, hypoparathyroidism
◍ Water tends to move together with which electrolyte?a) Magnesiumb)
