TEST BANK FOR PATHOPHYSIOLOGY
THE BIOLOGIC BASIS FOR DISEASE IN
ADULTS AND CHILDREN 8 TH EDITION
BY KATHRYN L. MCCANCE
COMPREHENSIVE STUDY GUIDE 2026
FULL QUESTIONS AND SOLUTIONS
GRADED A+
◍ Plasma weight.
Answer: The weight of plasma is influenced more by solutes such as
proteins and glucose than by water.
◍ Homozygous.
Answer: Two dominant or recessive alleles
◍ Cor pulmonale.
Answer: Disease of the heart characterized by hypertrophy and dilatation of
the right ventricle and secondary to disease of the lungs or their blood
vessels
◍ Hypersecretion of aldosterone.
Answer: An increased production of aldosterone, often leading to
hypertension and hypokalemia.
◍ The term cancer refers to:A) dysplasia.B) hyperplasia.C) metaplasia.D)
malignant neoplasm..
Answer: D
◍ Hypokalemia clinical manifestations.
, Answer: Include paralytic ileus, sinus bradycardia, and atrioventricular
block.
◍ Uniport.
Answer: Transport of a single molecule across membrane.
◍ Cytoplasm.
Answer: Fluid component of the cell, excluding nucleus.
◍ top 4 infections related to CA.
Answer: 1. HPV2. helicobactor pylori3. hep B4. hep C
◍ Cysts in breast tissue.
Answer: Fluid-filled sacs that complicate cancer detection.
◍ Integral protein.
Answer: Membrane protein that facilitates the attachment of a cell to the
extracellular matrix and signal transduction from the extracellular matrix to
the cell
◍ RAAS system.
Answer: decrease perfusion to kidneys releasing renin converts to
angiotensin I to angiotensin II which vasoconstrict & increase aldosterone-
keep K and H2O
◍ Endogenous pyrogens.
Answer: Fever-producing substance produced by phagocytic cells as they
destroy microorganisms within the host, prostaglandin E, Interleukin 1 and
6, tumor necrosis factor, interferon-gamma; act on preoptic nucleus of
hypothalamus
◍ prolactin secreting tumors.
Answer: in anterior pituitary called prolactinomas in woman and normally
cause galactorrhea
◍ Osmolarity.
Answer: A measurement of osmotic activity that is less preferred than
osmolality because it does not account for the weight of solutes in plasma.
,◍ Monocytes.
Answer: Enter later to replace leukocytes in inflammation.
◍ Diabetic ketoacidosis.
Answer: The buildup of byproducts of fat metabolism that occurs when
glucose is not available as a fuel source for the body because of insulin
deficiency.
◍ Eukaryotic cells.
Answer: Eukaryotic cells have a characteristic set of membrane-bound
intracellular compartments called organelles that include a well-defined
nucleus and are larger than prokaryotes.
◍ Preventative Health Care.
Answer: Measures taken to prevent diseases before they occur.
◍ point mutation of ras.
Answer: changes ras from proto-oncogene to oncogenepancreatic &
colorectal cancer
◍ white matter.
Answer: lies beneath the cerebral cortex and is composed of myelinated
nerve fibers which send messages to neurons
◍ Natriuretic peptides.
Answer: Hormones that decrease blood pressure and increase sodium and
water excretion.
◍ Turner Syndrome.
Answer: Condition with a single X chromosome present.
◍ Collectins.
Answer: Proteins produced by the lungs for immunity.
◍ Nasal congestion.
Answer: A symptom of acute sinusitis.
◍ Autoimmune reaction.
, Answer: A hypersensitivity reaction that involves failure of the development
of self-tolerance, leading to the immune system attacking the individual's
own tissues.
◍ Golgi bodies.
Answer: Proteins from the endoplasmic reticulum are processed and
packaged into secretory vesicles at the Golgi bodies.
◍ The term cancer refers to:
A. Dysplasia
B. Hyperplasia
C. Metaplasia
D. Malignant Neoplasm.
Answer: D. Malignant neoplasm
◍ Allergy.
Answer: An exaggerated immune response to a substance that is typically
harmless.
◍ Dendritic cell.
Answer: A type of antigen-presenting cell that plays a key role in the
immune response.
◍ Generational skipping.
Answer: X-linked traits can skip generations in families.
◍ Urodilatin.
Answer: A natriuretic peptide hormone that is synthesized in and released
from the kidney and functions in the regulation of water and sodium.
◍ Intravascular fluid.
Answer: Plasma present in the blood.
◍ SIADH.
Answer: characterized by high levels of ADH in the absence of normal
control mechanism- lethargy- decreased Na- sz- decreased plasma
osmolality- concentrated urine- lung ca- fluid volume overload- increase
THE BIOLOGIC BASIS FOR DISEASE IN
ADULTS AND CHILDREN 8 TH EDITION
BY KATHRYN L. MCCANCE
COMPREHENSIVE STUDY GUIDE 2026
FULL QUESTIONS AND SOLUTIONS
GRADED A+
◍ Plasma weight.
Answer: The weight of plasma is influenced more by solutes such as
proteins and glucose than by water.
◍ Homozygous.
Answer: Two dominant or recessive alleles
◍ Cor pulmonale.
Answer: Disease of the heart characterized by hypertrophy and dilatation of
the right ventricle and secondary to disease of the lungs or their blood
vessels
◍ Hypersecretion of aldosterone.
Answer: An increased production of aldosterone, often leading to
hypertension and hypokalemia.
◍ The term cancer refers to:A) dysplasia.B) hyperplasia.C) metaplasia.D)
malignant neoplasm..
Answer: D
◍ Hypokalemia clinical manifestations.
, Answer: Include paralytic ileus, sinus bradycardia, and atrioventricular
block.
◍ Uniport.
Answer: Transport of a single molecule across membrane.
◍ Cytoplasm.
Answer: Fluid component of the cell, excluding nucleus.
◍ top 4 infections related to CA.
Answer: 1. HPV2. helicobactor pylori3. hep B4. hep C
◍ Cysts in breast tissue.
Answer: Fluid-filled sacs that complicate cancer detection.
◍ Integral protein.
Answer: Membrane protein that facilitates the attachment of a cell to the
extracellular matrix and signal transduction from the extracellular matrix to
the cell
◍ RAAS system.
Answer: decrease perfusion to kidneys releasing renin converts to
angiotensin I to angiotensin II which vasoconstrict & increase aldosterone-
keep K and H2O
◍ Endogenous pyrogens.
Answer: Fever-producing substance produced by phagocytic cells as they
destroy microorganisms within the host, prostaglandin E, Interleukin 1 and
6, tumor necrosis factor, interferon-gamma; act on preoptic nucleus of
hypothalamus
◍ prolactin secreting tumors.
Answer: in anterior pituitary called prolactinomas in woman and normally
cause galactorrhea
◍ Osmolarity.
Answer: A measurement of osmotic activity that is less preferred than
osmolality because it does not account for the weight of solutes in plasma.
,◍ Monocytes.
Answer: Enter later to replace leukocytes in inflammation.
◍ Diabetic ketoacidosis.
Answer: The buildup of byproducts of fat metabolism that occurs when
glucose is not available as a fuel source for the body because of insulin
deficiency.
◍ Eukaryotic cells.
Answer: Eukaryotic cells have a characteristic set of membrane-bound
intracellular compartments called organelles that include a well-defined
nucleus and are larger than prokaryotes.
◍ Preventative Health Care.
Answer: Measures taken to prevent diseases before they occur.
◍ point mutation of ras.
Answer: changes ras from proto-oncogene to oncogenepancreatic &
colorectal cancer
◍ white matter.
Answer: lies beneath the cerebral cortex and is composed of myelinated
nerve fibers which send messages to neurons
◍ Natriuretic peptides.
Answer: Hormones that decrease blood pressure and increase sodium and
water excretion.
◍ Turner Syndrome.
Answer: Condition with a single X chromosome present.
◍ Collectins.
Answer: Proteins produced by the lungs for immunity.
◍ Nasal congestion.
Answer: A symptom of acute sinusitis.
◍ Autoimmune reaction.
, Answer: A hypersensitivity reaction that involves failure of the development
of self-tolerance, leading to the immune system attacking the individual's
own tissues.
◍ Golgi bodies.
Answer: Proteins from the endoplasmic reticulum are processed and
packaged into secretory vesicles at the Golgi bodies.
◍ The term cancer refers to:
A. Dysplasia
B. Hyperplasia
C. Metaplasia
D. Malignant Neoplasm.
Answer: D. Malignant neoplasm
◍ Allergy.
Answer: An exaggerated immune response to a substance that is typically
harmless.
◍ Dendritic cell.
Answer: A type of antigen-presenting cell that plays a key role in the
immune response.
◍ Generational skipping.
Answer: X-linked traits can skip generations in families.
◍ Urodilatin.
Answer: A natriuretic peptide hormone that is synthesized in and released
from the kidney and functions in the regulation of water and sodium.
◍ Intravascular fluid.
Answer: Plasma present in the blood.
◍ SIADH.
Answer: characterized by high levels of ADH in the absence of normal
control mechanism- lethargy- decreased Na- sz- decreased plasma
osmolality- concentrated urine- lung ca- fluid volume overload- increase
