PN HESI Pharmacology Exam 2026/2027 – Complete Question Practice Test Bank with Answers & Rationale | Practical Nursing Pharm HESI Prep | High Yield Dosage Calculations, Cardiac, Psych, Endocrine & NCLEX-PN Next-Gen Prep

PN HESI Pharmacology Exam 2026/2027 – Complete
Question Practice Test Bank with Answers & Rationale |
Practical Nursing Pharm HESI Prep | High Yield Dosage
Calculations, Cardiac, Psych, Endocrine & NCLEX-PN
Next-Gen Prep
SECTION 1: DOSAGE CALCULATIONS
Question 1
The provider orders 500 mg of amoxicillin PO. The pharmacy supplies 250 mg/5
mL suspension. How many mL should the nurse administer?
A) 5 mL
B) 10 mL
C) 15 mL
D) 20 mL
Correct Answer: B) 10 mL
Rationale: Use formula: Desired/Have × Quantity = 500/250 × 5 mL = 2 × 5 = 10
mL.


Question 2
The nurse is calculating an IV infusion rate. The provider orders 1000 mL of
normal saline to infuse over 8 hours. The IV set delivers 15 gtt/mL. What is the
flow rate in gtt/min?
A) 21 gtt/min
B) 31 gtt/min
C) 41 gtt/min
D) 51 gtt/min
Correct Answer: B) 31 gtt/min
Rationale: (1000 mL ÷ 480 min) × 15 = 2.08 × 15 = 31.2 → 31 gtt/min.

,Question 3
A client is prescribed heparin 5000 units subcutaneous. The vial contains 10,000
units/mL. How many mL should the nurse administer?
A) 0.5 mL
B) 1 mL
C) 1.5 mL
D) 2 mL
Correct Answer: A) 0.5 mL
Rationale: 5000/10,000 × 1 mL = 0.5 mL.


Question 4
The provider orders morphine sulfate 4 mg IV push. The vial contains 10 mg/mL.
How many mL should the nurse draw up?
A) 0.2 mL
B) 0.4 mL
C) 0.6 mL
D) 0.8 mL
Correct Answer: B) 0.4 mL
Rationale: 4/10 × 1 mL = 0.4 mL.


Question 5
A child weighing 30 kg is prescribed amoxicillin 20 mg/kg/day divided into two
doses. What is the amount per dose?
A) 150 mg
B) 200 mg
C) 300 mg
D) 600 mg

,Correct Answer: C) 300 mg
Rationale: Total daily = 30 × 20 = 600 mg/day. Divided into 2 doses = 600/2 = 300
mg per dose.


Question 6
The nurse is preparing to administer 40 mEq of potassium chloride IV. The vial
contains 20 mEq/10 mL. How many mL should the nurse administer?
A) 10 mL
B) 15 mL
C) 20 mL
D) 25 mL
Correct Answer: C) 20 mL
Rationale: 40/20 × 10 mL = 20 mL.


Question 7
The provider orders digoxin 0.125 mg PO daily. The pharmacy supplies 0.25 mg
tablets. How many tablets should the nurse administer?
A) 0.25 tablet
B) 0.5 tablet
C) 1 tablet
D) 2 tablets
Correct Answer: B) 0.5 tablet
Rationale: 0.125/0.25 = 0.5 tablet.


Question 8
An IV infusion of 500 mL is to infuse over 4 hours. The drop factor is 20 gtt/mL.
What is the rate in gtt/min?

, A) 21 gtt/min
B) 32 gtt/min
C) 42 gtt/min
D) 52 gtt/min
Correct Answer: C) 42 gtt/min
Rationale: (500 mL ÷ 240 min) × 20 = 2.08 × 20 = 41.6 → 42 gtt/min.


Question 9
A client is prescribed furosemide 80 mg IV push. The vial contains 40 mg/4 mL.
How many mL should the nurse administer?
A) 4 mL
B) 6 mL
C) 8 mL
D) 10 mL
Correct Answer: C) 8 mL
Rationale: 80/40 × 4 mL = 8 mL.


Question 10
The provider orders ceftriaxone 1 g IM. The pharmacy supplies a vial with 2 g
powder and instructions to add 4 mL diluent for a concentration of 500 mg/mL.
How many mL should the nurse administer?
A) 1 mL
B) 2 mL
C) 3 mL
D) 4 mL
Correct Answer: B) 2 mL
Rationale: 1 g = 1000 mg. Concentration = 500 mg/mL. 1000/500 = 2 mL.