QUESTIONS AND ANSWERS FOR
GENETICS EXAM 3 | GRADED A+ |
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,Which of the following statements about promoter mutations -Up promoter mutations cause the promoter sequence to be more like the consensus
is true? sequence
-Up promoter mutations cause the promoter sequence to be -Down promoter mutations decrease the affinity of transcription factors to the promoter
more like the consensus sequence
-Down promoter mutations occur in the 3'-UTR of the gene
-Down promoter mutations decrease the affinity of
transcription factors to the promoter
-Up promoter mutations occur in the coding sequence of the
gene
In a natural population, a __________________-_____________ genotype is Wild-type
the most common one
True or False: The phenotypic effects of a mutation are either False
detrimental or neutral
A ___________ mutation refers to a mutation in which just one base Point
is changed within the DNA sequence
A mutation that does not change the amino acid sequence of Silent
a polypeptide is known as a ____________ mutation
A second mutation that occurs in a different site than the firsts Suppressor
mutation, and which converts the mutant back to the wild-type
phenotype, is best referred to as a ___________________ mutation
Mutations that occur in a promoter sequence can be divided Up; Down
into two types: _____________ promoter mutations increase the
transcription rate, while ______________ promoter mutations
decrease it
The region where two chromosome pieces break and re- Breakpoint
attach to the other chromosome pieces is called a
chromosomal ________________
The wild type genotype or phenotype is the one that is Typically found in nature
The term germ line is used to describe The cells that produce sperm and egg
, Mutations can be caused in two main ways: 1. _______________ 1. Spontaneous
mutations are the result of natural biological or chemical 2. Induced
processes; and 2. ________________ mutations are produced by
environmental agents
What is the effect of a suppressor mutation? It suppresses the phenotypic effect of another mutation
A breakpoint refers to the region Where two chromosome pieces break and rejoin with other chromosome pieces
Mutations that remove an adenine or guanine from the DNA Depurinations
are known as
Cells that give rise to the gametes such as eggs and sperm Germ cells
are called __________ ____________
Products of oxygen metabolism, such as hydrogen peroxide, Reactive Oxygen
superoxide, and hydroxyl radical, are collectively called
____________ ___________ species
The phenomenon in which a repeated sequence of three Trinucleotide repeat expansion
bases increases in number generation after generation is
called ______________ __________ __________
Errors in DNA replication are examples of _____________ mutations, Spontaneous; Induced
while mutations caused by ultraviolet light are _______________
mutations
A mutagen is an Agent that causes mutations
Nitrous acid is a mutagen that acts via that process of Deamination
The removal of a purine from DNA is called ___________________ Depurination
Alkylating agents covalently attach ________________ or _______________ Methyl; Ethyl
groups to DNA bases, and thus dirupt their normal base
pairing properties