Week 7 Quiz: SCI 251 / SCI251
(Latest ) Microbiology |
Questions & Answers 100% Correct -
Nightingale
Question:
General Goal of Antimicrobial Therapy
Answer:
To destroy or inhibit microbes without causing significant damage to the
host.
Question:
Five Basic Mechanisms of Antimicrobial Drugs
Answer:
Inhibition of –
Cell wall
Protein
Nucleic acid synthesis
Cell membrane disruption
Metabolic antagonism.
,Question:
Narrow-Spectrum Drugs
Answer:
Antimicrobials effective against only a limited, specific group of microbes.
Question:
Broad-Spectrum Drugs
Answer:
Antimicrobials effective against a wide variety of both Gram-positive and
Gram-negative bacteria.
Question:
Factors in Selecting Antimicrobial Drugs
Answer:
Microbe identity
Drug susceptibility
Infection site
Patient factors (e.g., allergies, age).
, Question:
Therapeutic Index (TI)
Answer:
The ratio of the toxic dose to the therapeutic dose; higher is safer.
Question:
Three Categories of Antimicrobial Side Effects
Answer:
Direct organ toxicity
Allergic (hypersensitivity) reactions
Disruption of normal microflora.
Question:
Origin of Drug Resistance
Answer:
Spontaneous genetic mutations or horizontal gene transfer via plasmids
(conjugation, transduction, transformation).
(Latest ) Microbiology |
Questions & Answers 100% Correct -
Nightingale
Question:
General Goal of Antimicrobial Therapy
Answer:
To destroy or inhibit microbes without causing significant damage to the
host.
Question:
Five Basic Mechanisms of Antimicrobial Drugs
Answer:
Inhibition of –
Cell wall
Protein
Nucleic acid synthesis
Cell membrane disruption
Metabolic antagonism.
,Question:
Narrow-Spectrum Drugs
Answer:
Antimicrobials effective against only a limited, specific group of microbes.
Question:
Broad-Spectrum Drugs
Answer:
Antimicrobials effective against a wide variety of both Gram-positive and
Gram-negative bacteria.
Question:
Factors in Selecting Antimicrobial Drugs
Answer:
Microbe identity
Drug susceptibility
Infection site
Patient factors (e.g., allergies, age).
, Question:
Therapeutic Index (TI)
Answer:
The ratio of the toxic dose to the therapeutic dose; higher is safer.
Question:
Three Categories of Antimicrobial Side Effects
Answer:
Direct organ toxicity
Allergic (hypersensitivity) reactions
Disruption of normal microflora.
Question:
Origin of Drug Resistance
Answer:
Spontaneous genetic mutations or horizontal gene transfer via plasmids
(conjugation, transduction, transformation).
