WGU D027 Objective Assessment Review
(Latest 2023/ 2024 Update) Advanced
Pathopharmacological Foundations|
Questions and Verified Answers| 100%
Correct| Grade A exam 3
1. A 26-year-old female presents to urgent care with complaints of
extreme fatigue, muscle aches, abdominal pain, numbness and
tingling in her extremities, and bloating. She explains that she has
been experiencing gastrointestinal upset after meals and has not had
a bowel movement for the past four days. She reports using over-the-
counter, anti-diarrheal products last week to combat diarrhea. She
denies having any chronic diseases. The assessment findings include a
blood pressure of 108/71 mm Hg, pulse of 82 beats per minute, and
respirations of 20 breaths per minute. The abdomen is distended and
firm. Bowel sounds are present in all four quadrants. The patient has a
steady gait, though verbally complains of feeling weak and off balance
upon ambulation. Following antibody testing, Celiac disease is
suspected.
Which follow-up tissue test, the gold standard for this suspected
diagnosis, should be ordered?
A. Endoscopy with stomach biopsy
B. Colonoscopy with large intestine biopsy
C. Endoscopy with small intestine biopsy
D. Colonoscopy with rectal biopsy Answer:- C. Endoscopy with small
intestine biopsy
2. A 44-year-old woman has recently been diagnosed with advanced
metastatic non-small-cell lung cancer. Genetic testing is ordered to
determine if the patient's tumor has any genomic alterations and to
guide treatment decisions. A few weeks later, the patient's test results
,come back positive for a genetic mutation. The APN starts osimertinib
(Tagrisso).
Based on this information, what type of genetic mutation does this
patient have?
A. ALK mutation
B. EGFR mutation
C. BRCA mutation
D. MET amplification mutation Answer:- B. EGFR mutation
3. A 20-year-old male meets with an advanced professional nurse
(APN) to discuss symptoms that have been slowly progressing over the
past several years. He is mainly concerned because he has been
falling frequently. Since childhood, his gait has consisted of walking on
his toes. During middle school, he was able to participate in sports but
was unable to participate in high school sports due to difficulty with
running and jumping. Lately, he has noticed it takes longer and is
more difficult to change positions from sitting to standing than it used
to in the past. He has also been waking up with muscle and joint
stiffness. The APRN notes that his family history is not significant for
any chronic or genetic diseases.
Which condition is likely to be the cause of these symptoms?
A. Becker muscular dystrophy
B. Myotonic dystrophy
C. Facioscapulohumeral muscular dystrophy (FSHD)
D. Limb-girdle muscular dystrophy Answer:- A. Becker muscular
dystrophy
4. Which statement should the provider give the patient regarding the
pathophysiology of SLE and its relation to thrombocytopenia?
A. SLE disrupts immune homeostasis and promotes development of
self-re-active antibodies.
, B. SLE causes a cross-reaction of antibodies with normal platelet
antigens.
C. SLE causes a defect in the number and function of regulatory B cells.
D. SLE increases megakaryocyte maturation. Answer:- A. SLE disrupts
immune homeostasis and promotes development of self-reactive
antibodies
5. A female patient presents to an office to establish care. Her previous
primary care provider told her to follow up regarding an elevated
ferritin level. She has no previous medical history and is currently
asymptomatic. She is concerned about the elevated ferritin and would
like to know if she should be worried.
What should the provider do next for this patient?
A. Order a liver function test
B. Order a renal ultrasound
C. Refer her for a bone marrow biopsy
D. Order a thyroid panel Answer:- A. Order a liver function test
6. A 75-year-old female presents to the emergency department with
an irregular heart rate of 130.
What can be ascertained about this patient's findings given the limited
information?
A. She has a normal sinus rhythm and needs her heart rate controlled
with metoprolol (Lopressor).
B. She is diagnosed with atrial fibrillation and needs her heart rate
controlled with metoprolol (Lopressor).
C. She is diagnosed with ventricular tachycardia and needs her heart
rhythm controlled with metoprolol (Lopressor).
D. She is diagnosed with torsades de pointes and needs her heart rate
con-
trolled with magnesium. Answer:- B. She is diagnosed with atrial
fibrillation and needs her heart rate controlled with metoprolol
(Lopressor)
(Latest 2023/ 2024 Update) Advanced
Pathopharmacological Foundations|
Questions and Verified Answers| 100%
Correct| Grade A exam 3
1. A 26-year-old female presents to urgent care with complaints of
extreme fatigue, muscle aches, abdominal pain, numbness and
tingling in her extremities, and bloating. She explains that she has
been experiencing gastrointestinal upset after meals and has not had
a bowel movement for the past four days. She reports using over-the-
counter, anti-diarrheal products last week to combat diarrhea. She
denies having any chronic diseases. The assessment findings include a
blood pressure of 108/71 mm Hg, pulse of 82 beats per minute, and
respirations of 20 breaths per minute. The abdomen is distended and
firm. Bowel sounds are present in all four quadrants. The patient has a
steady gait, though verbally complains of feeling weak and off balance
upon ambulation. Following antibody testing, Celiac disease is
suspected.
Which follow-up tissue test, the gold standard for this suspected
diagnosis, should be ordered?
A. Endoscopy with stomach biopsy
B. Colonoscopy with large intestine biopsy
C. Endoscopy with small intestine biopsy
D. Colonoscopy with rectal biopsy Answer:- C. Endoscopy with small
intestine biopsy
2. A 44-year-old woman has recently been diagnosed with advanced
metastatic non-small-cell lung cancer. Genetic testing is ordered to
determine if the patient's tumor has any genomic alterations and to
guide treatment decisions. A few weeks later, the patient's test results
,come back positive for a genetic mutation. The APN starts osimertinib
(Tagrisso).
Based on this information, what type of genetic mutation does this
patient have?
A. ALK mutation
B. EGFR mutation
C. BRCA mutation
D. MET amplification mutation Answer:- B. EGFR mutation
3. A 20-year-old male meets with an advanced professional nurse
(APN) to discuss symptoms that have been slowly progressing over the
past several years. He is mainly concerned because he has been
falling frequently. Since childhood, his gait has consisted of walking on
his toes. During middle school, he was able to participate in sports but
was unable to participate in high school sports due to difficulty with
running and jumping. Lately, he has noticed it takes longer and is
more difficult to change positions from sitting to standing than it used
to in the past. He has also been waking up with muscle and joint
stiffness. The APRN notes that his family history is not significant for
any chronic or genetic diseases.
Which condition is likely to be the cause of these symptoms?
A. Becker muscular dystrophy
B. Myotonic dystrophy
C. Facioscapulohumeral muscular dystrophy (FSHD)
D. Limb-girdle muscular dystrophy Answer:- A. Becker muscular
dystrophy
4. Which statement should the provider give the patient regarding the
pathophysiology of SLE and its relation to thrombocytopenia?
A. SLE disrupts immune homeostasis and promotes development of
self-re-active antibodies.
, B. SLE causes a cross-reaction of antibodies with normal platelet
antigens.
C. SLE causes a defect in the number and function of regulatory B cells.
D. SLE increases megakaryocyte maturation. Answer:- A. SLE disrupts
immune homeostasis and promotes development of self-reactive
antibodies
5. A female patient presents to an office to establish care. Her previous
primary care provider told her to follow up regarding an elevated
ferritin level. She has no previous medical history and is currently
asymptomatic. She is concerned about the elevated ferritin and would
like to know if she should be worried.
What should the provider do next for this patient?
A. Order a liver function test
B. Order a renal ultrasound
C. Refer her for a bone marrow biopsy
D. Order a thyroid panel Answer:- A. Order a liver function test
6. A 75-year-old female presents to the emergency department with
an irregular heart rate of 130.
What can be ascertained about this patient's findings given the limited
information?
A. She has a normal sinus rhythm and needs her heart rate controlled
with metoprolol (Lopressor).
B. She is diagnosed with atrial fibrillation and needs her heart rate
controlled with metoprolol (Lopressor).
C. She is diagnosed with ventricular tachycardia and needs her heart
rhythm controlled with metoprolol (Lopressor).
D. She is diagnosed with torsades de pointes and needs her heart rate
con-
trolled with magnesium. Answer:- B. She is diagnosed with atrial
fibrillation and needs her heart rate controlled with metoprolol
(Lopressor)