WGU D027 Objective Assessment Review
(Latest 2026/ 2027 Update) Advanced
Pathopharmacological Foundations|
Questions and Verified Answers| 100%
Correct| Grade A exam1
Answer: A genetic or a carrier test
Q: A 23-year-old woman comes in for prenatal
counseling. While completing her family history she
reports her brother has cystic fibrosis. She does not
know if she is a carrier. She asks if her children
will be affected by the disease. What is an accurate
way to determine the likelihood of this patient's
children being affected?
Answer: kleinfelters
Q: A 31-year-old man comes into the office for
an exam. He is 6' 5 \ with a high-pitched voice
and he has a moderate degree of mental impairment. It
is discovered upon exam that his body hair is sparse
his testes are small and he has gynecomastia. Which
genetic disorder should this patient be tested for?
Answer: may begin to waddle walk on their toes
or push their abdomen forward when walking
Q: sign of becker muscle dystrophy in kids?
Answer: 100%
Q: A six-month-old female infant with failure
to thrive comes in to the office with her parents. It
is noticed upon exam that the patient has facial
deformities and is jaundiced. A complete blood count
(CBC) is ordered which reveals anemia. When that
patient's blood is examined under a microscope the
red blood cells appear small and abnormally shaped. A
mutational analysis is ordered and alpha thalassemia
,is diagnosed. What is the likelihood of incidence of
these parent's future children having alpha
thalassemia?
Answer: Doppler U/S
Q: A 64-year-old male truck driver comes in
complaining of pain in his lower left calf. He states
he drives eight to ten hours per day. Upon exam
swelling and mottled coloring are noted in the
patient's calf. A D-dimer test is ordered and comes
back positive. Which additional test should be ordered
to confirm a diagnosis in this patient?
Answer: Completing an ambulatory blood pressure
assessment
Q: A 54-year-old man comes into a clinic for a
routine visit. His initial BP is 148/92. After a
recheck 15 minutes later his BP is 140/90. He states
he suffers from \ white coat hypertension.\ He
states he has no history of high blood pressure and no
family history of high blood pressure. Which nursing
intervention would assist this patient in receiving a
clinical diagnosis of hypertension?
Answer: Lupus
Q: A 58-year-old woman comes in complaining of
retrosternal chest pain worsening with recumbent
position. She states she has had a low-grade fever for
two days. Upon exam the patient has a friction rub.
An EKG reveals sinus tachycardia with inflammatory
changes. An ultrasound is performed and she is
diagnosed with an acute pericarditis. Which condition
would make pericarditis more likely in this patient?
Answer: Lipitor 20 mg
Q: A 54-year-old Caucasian man comes in for a
lab review. His lipids reveal an LDL of 180 an HDL
of 52 and triglycerides of 326. He has no history of
,atherosclerotic cardiovascular disease (ASCVD) or
diabetes. His blood pressure is 118/64. He has a pulse
rate of 64 and he weighs 320 lb. He smokes one pack
of cigarettes per day and his ASCVD risk score is
12.8. Which medication should this patient be started
on?
Answer: Stop angiotensin receptor blockers (ARB)
and add sacubitril/valsartan (Entresto) if BNP high
replace ARB ACE or ARNI
Q: A 73-year-old man with Systolic congestive
heart failure (CHF) with reduced ejection fraction
(HFrEF) comes to a clinic complaining of shortness of
breath. He is currently taking 6.25 mg carvedilol
(Coreg) twice a day and 50 mg losartan (Cozaar) and 20
mg furosemide (Lasix) daily. His oxygen saturation is
95% and he has a pulse of 64. His BP is 138/82 and
his BNP is 1150. Using the 2017 heart failure
guidelines which medication change should be
recommended for this patient?
Answer: BBs BB contraindicated in pts COPD/
asthma
Q: A 78-year-old man comes in with stable
angina. He reports he has been having more angina
recently. He is currently taking the following
medications: lisinopril (Zestril) atorvastatin
(Lipitor) aspirin and nitrostat PRN for chest
pain. He has a history of COPD with bronchospasm. His
blood pressure is 145/88 and he has a pulse of 74.
Which class of medications should be avoided for this
patient?
Answer: Start metformin XR (Glucophage XR) 250
mg once a day and reevaluate after Ramadan
Q: A 45-year-old Muslim woman presents to a
clinic for an intervention for her type 2 diabetes.
She is prescribed metformin (Glucophage) 500 mg BID.
During a follow-up phone call a week later it is
, discovered she has not been taking the metformin. A
second visit is scheduled. During this visit she
states that she cannot take the medication as
prescribed because it is Ramadan a month-long period
of religious observances. Due to her religious beliefs
she fasts from dawn to sunset. When the pharmacist
told her to take metformin with breakfast and dinner
she decided not to start the medication due to her
fasting. Which nursing intervention should be made for
this patient?
Answer: While insulin did have porcine sources
in the past it is now synthetically made.
Q: A 45-year-old Jewish man is visiting a
clinic for an adjustment of his diabetes medications.
Though the patient is taking oral medications his
blood sugar levels continue to increase and a
decision is made to start him on insulin. Although the
patient is comfortable with the concept of starting
insulin he is concerned with the formulation of the
insulin saying \ I heard insulin was made from
pigs. If that is the case I cannot take it due to my
faith.\ Which response should be given to this
patient?
Answer: Lovastatin (Mevacor) red yeast rice
contains this
Q: A 45-year-old man reports his preference
for natural methods of treating illness. He states he
takes natural supplements that he orders from China to
boost his health and well-being. One of the
supplements he takes daily is red yeast rice. Which
medication should be avoided with this patient's
supplement?
Answer: Lisinopril
Q: A 40-year-old man presents to a clinic with
an onset of a frequent cough. The patient states the
cough started when he started his new blood pressure
(Latest 2026/ 2027 Update) Advanced
Pathopharmacological Foundations|
Questions and Verified Answers| 100%
Correct| Grade A exam1
Answer: A genetic or a carrier test
Q: A 23-year-old woman comes in for prenatal
counseling. While completing her family history she
reports her brother has cystic fibrosis. She does not
know if she is a carrier. She asks if her children
will be affected by the disease. What is an accurate
way to determine the likelihood of this patient's
children being affected?
Answer: kleinfelters
Q: A 31-year-old man comes into the office for
an exam. He is 6' 5 \ with a high-pitched voice
and he has a moderate degree of mental impairment. It
is discovered upon exam that his body hair is sparse
his testes are small and he has gynecomastia. Which
genetic disorder should this patient be tested for?
Answer: may begin to waddle walk on their toes
or push their abdomen forward when walking
Q: sign of becker muscle dystrophy in kids?
Answer: 100%
Q: A six-month-old female infant with failure
to thrive comes in to the office with her parents. It
is noticed upon exam that the patient has facial
deformities and is jaundiced. A complete blood count
(CBC) is ordered which reveals anemia. When that
patient's blood is examined under a microscope the
red blood cells appear small and abnormally shaped. A
mutational analysis is ordered and alpha thalassemia
,is diagnosed. What is the likelihood of incidence of
these parent's future children having alpha
thalassemia?
Answer: Doppler U/S
Q: A 64-year-old male truck driver comes in
complaining of pain in his lower left calf. He states
he drives eight to ten hours per day. Upon exam
swelling and mottled coloring are noted in the
patient's calf. A D-dimer test is ordered and comes
back positive. Which additional test should be ordered
to confirm a diagnosis in this patient?
Answer: Completing an ambulatory blood pressure
assessment
Q: A 54-year-old man comes into a clinic for a
routine visit. His initial BP is 148/92. After a
recheck 15 minutes later his BP is 140/90. He states
he suffers from \ white coat hypertension.\ He
states he has no history of high blood pressure and no
family history of high blood pressure. Which nursing
intervention would assist this patient in receiving a
clinical diagnosis of hypertension?
Answer: Lupus
Q: A 58-year-old woman comes in complaining of
retrosternal chest pain worsening with recumbent
position. She states she has had a low-grade fever for
two days. Upon exam the patient has a friction rub.
An EKG reveals sinus tachycardia with inflammatory
changes. An ultrasound is performed and she is
diagnosed with an acute pericarditis. Which condition
would make pericarditis more likely in this patient?
Answer: Lipitor 20 mg
Q: A 54-year-old Caucasian man comes in for a
lab review. His lipids reveal an LDL of 180 an HDL
of 52 and triglycerides of 326. He has no history of
,atherosclerotic cardiovascular disease (ASCVD) or
diabetes. His blood pressure is 118/64. He has a pulse
rate of 64 and he weighs 320 lb. He smokes one pack
of cigarettes per day and his ASCVD risk score is
12.8. Which medication should this patient be started
on?
Answer: Stop angiotensin receptor blockers (ARB)
and add sacubitril/valsartan (Entresto) if BNP high
replace ARB ACE or ARNI
Q: A 73-year-old man with Systolic congestive
heart failure (CHF) with reduced ejection fraction
(HFrEF) comes to a clinic complaining of shortness of
breath. He is currently taking 6.25 mg carvedilol
(Coreg) twice a day and 50 mg losartan (Cozaar) and 20
mg furosemide (Lasix) daily. His oxygen saturation is
95% and he has a pulse of 64. His BP is 138/82 and
his BNP is 1150. Using the 2017 heart failure
guidelines which medication change should be
recommended for this patient?
Answer: BBs BB contraindicated in pts COPD/
asthma
Q: A 78-year-old man comes in with stable
angina. He reports he has been having more angina
recently. He is currently taking the following
medications: lisinopril (Zestril) atorvastatin
(Lipitor) aspirin and nitrostat PRN for chest
pain. He has a history of COPD with bronchospasm. His
blood pressure is 145/88 and he has a pulse of 74.
Which class of medications should be avoided for this
patient?
Answer: Start metformin XR (Glucophage XR) 250
mg once a day and reevaluate after Ramadan
Q: A 45-year-old Muslim woman presents to a
clinic for an intervention for her type 2 diabetes.
She is prescribed metformin (Glucophage) 500 mg BID.
During a follow-up phone call a week later it is
, discovered she has not been taking the metformin. A
second visit is scheduled. During this visit she
states that she cannot take the medication as
prescribed because it is Ramadan a month-long period
of religious observances. Due to her religious beliefs
she fasts from dawn to sunset. When the pharmacist
told her to take metformin with breakfast and dinner
she decided not to start the medication due to her
fasting. Which nursing intervention should be made for
this patient?
Answer: While insulin did have porcine sources
in the past it is now synthetically made.
Q: A 45-year-old Jewish man is visiting a
clinic for an adjustment of his diabetes medications.
Though the patient is taking oral medications his
blood sugar levels continue to increase and a
decision is made to start him on insulin. Although the
patient is comfortable with the concept of starting
insulin he is concerned with the formulation of the
insulin saying \ I heard insulin was made from
pigs. If that is the case I cannot take it due to my
faith.\ Which response should be given to this
patient?
Answer: Lovastatin (Mevacor) red yeast rice
contains this
Q: A 45-year-old man reports his preference
for natural methods of treating illness. He states he
takes natural supplements that he orders from China to
boost his health and well-being. One of the
supplements he takes daily is red yeast rice. Which
medication should be avoided with this patient's
supplement?
Answer: Lisinopril
Q: A 40-year-old man presents to a clinic with
an onset of a frequent cough. The patient states the
cough started when he started his new blood pressure
