HNG 540: Test 1 Questions with 100% Correct
Answers
Q: A patient's nutritional intake and laboratory results reflect hypoalbuminemia. This
is critical to prescribing because
A: Distribution of drugs to target tissue may be affected.
Q: Drugs that have a significant first-pass effect
A: Are rapidly metabolized by the liver and may have little if any desired action.
Q: The route of excretion of a volatile drug will likely be the
A: Lungs.
Q: Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a
storage reservoir of the drug. Storage reservoirs
A: Increase the length of time a drug is available and active.
Q: The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's
A: Biological half-life.
Q: Azithromycin dosing requires that the first day's dosage be twice those of the other 4
days of the prescription. This is considered a loading dose. A loading dose
A: Rapidly achieves drug levels in the therapeutic range.
Q: The point in time on the drug concentration curve that indicates the first sign of a
therapeutic effect is the
A: Onset of action.
Q: Phenytoin requires that a trough level be drawn. Peak and trough levels are done
, A: To determine if a drug is in the therapeutic range.
Q: A laboratory result indicates that the peak level for a drug is above the minimum
toxic concentration. This means that the
A: Concentration will produce an adverse response.
Q: Drugs that are receptor agonists may demonstrate what property?
A: Desensitization or downregulation with continuous use.
Q: Drugs that are receptor antagonists
such as beta blockers, may cause, A: An exaggerated response if abruptly discontinued.
Q: Factors that affect gastric drug absorption include
A: Lipid solubility of the drug.
Q: Drugs administered via IV
A: Begin distribution into the body immediately.
Q: When a medication is added to a regimen for a synergistic effect
the combined effect of the drugs is, A: Greater than the sum of the effects of each drug
individually.
Q: Which of the following statements about bioavailability is true?
A: Bioavailability issues are especially important for drugs with narrow therapeutic ranges or
sustained-release mechanisms.
Q: Which of the following statements about the major distribution barriers (blood-
brain or fetal-placental) is true?
A: The blood-brain barrier slows the entry of many drugs into and from brain cells.
Answers
Q: A patient's nutritional intake and laboratory results reflect hypoalbuminemia. This
is critical to prescribing because
A: Distribution of drugs to target tissue may be affected.
Q: Drugs that have a significant first-pass effect
A: Are rapidly metabolized by the liver and may have little if any desired action.
Q: The route of excretion of a volatile drug will likely be the
A: Lungs.
Q: Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a
storage reservoir of the drug. Storage reservoirs
A: Increase the length of time a drug is available and active.
Q: The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's
A: Biological half-life.
Q: Azithromycin dosing requires that the first day's dosage be twice those of the other 4
days of the prescription. This is considered a loading dose. A loading dose
A: Rapidly achieves drug levels in the therapeutic range.
Q: The point in time on the drug concentration curve that indicates the first sign of a
therapeutic effect is the
A: Onset of action.
Q: Phenytoin requires that a trough level be drawn. Peak and trough levels are done
, A: To determine if a drug is in the therapeutic range.
Q: A laboratory result indicates that the peak level for a drug is above the minimum
toxic concentration. This means that the
A: Concentration will produce an adverse response.
Q: Drugs that are receptor agonists may demonstrate what property?
A: Desensitization or downregulation with continuous use.
Q: Drugs that are receptor antagonists
such as beta blockers, may cause, A: An exaggerated response if abruptly discontinued.
Q: Factors that affect gastric drug absorption include
A: Lipid solubility of the drug.
Q: Drugs administered via IV
A: Begin distribution into the body immediately.
Q: When a medication is added to a regimen for a synergistic effect
the combined effect of the drugs is, A: Greater than the sum of the effects of each drug
individually.
Q: Which of the following statements about bioavailability is true?
A: Bioavailability issues are especially important for drugs with narrow therapeutic ranges or
sustained-release mechanisms.
Q: Which of the following statements about the major distribution barriers (blood-
brain or fetal-placental) is true?
A: The blood-brain barrier slows the entry of many drugs into and from brain cells.
