PRACTICE BANK | 2026/2027 EDITION |200 QUESTIONS WITH
VERIFIED ANSWERS & DETAILED CLINICAL RATIONALES 100% VERIFIED
SOLUTIONS | A+ GRADED | PASS GUARANTEED
SECTION 1: ADVANCED PHYSICAL ASSESSMENT & DIAGNOSTIC REASONING
(Questions 1-30)
Q1. During cardiac auscultation, you hear a mid-systolic click followed by a late
systolic murmur at the apex, best heard with the bell of the stethoscope. This
finding is most consistent with:
A) Aortic stenosis
B) Mitral valve prolapse
C) Hypertrophic cardiomyopathy
D) Tricuspid regurgitation
Answer: B
Rationale: Mitral valve prolapse is characterized by a mid-systolic click followed
by a late systolic murmur at the apex. The mid-systolic click represents the
sudden tensing of the chordae tendineae as the mitral valve leaflets bulge into
the left atrium during systole. The late systolic murmur represents mitral
regurgitation that occurs as the valve fails to coapt properly. This murmur is
best heard with the bell of the stethoscope at the apex and may be accentuated
by maneuvers that decrease left ventricular volume (standing, Valsalva) because
smaller ventricular size allows more leaflet prolapse.
Q2. A 58-year-old male presents with chest pressure that occurs with exertion
and resolves with rest. He describes the pain as a "heavy pressure" in the
substernal area radiating to the left jaw. He has a history of hypertension and
hyperlipidemia. Which finding is most consistent with stable angina?
A) Pain that is sharp and pleuritic, worsening with inspiration
B) Pain that is reproducible with palpation of the chest wall
C) Pain that is provoked by exertion and relieved within minutes by rest or
nitroglycerin
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,D) Pain that is constant for hours and associated with diaphoresis and nausea
Answer: C
Rationale: Stable angina is ischemic chest discomfort caused by fixed coronary
artery narrowing that cannot meet increased myocardial oxygen demand during
exertion or emotional stress. The pain is typically described as pressure,
squeezing, or heaviness in the substernal area with radiation to the jaw, neck,
or left arm. The key distinguishing feature is that it predictably occurs with
exertion and reliably resolves within 5-10 minutes with rest or nitroglycerin.
This predictable pattern differentiates stable angina from unstable angina or
myocardial infarction.
Q3. A 55-year-old female presents with severe, episodic right upper quadrant pain
that occurs 30-60 minutes after eating fatty meals. The pain radiates to her right
shoulder and lasts 2-3 hours. On examination, Murphy's sign is positive. Which
finding on abdominal ultrasound would confirm the suspected diagnosis?
A) Gallstones and gallbladder wall thickening
B) Pancreatic pseudocyst
C) Hepatic cyst
D) Appendiceal dilation
Answer: A
Rationale: This presentation is classic for acute cholecystitis. RUQ pain after
fatty meals is caused by gallbladder contraction stimulating the vagus nerve and
increasing pressure against an obstructed gallbladder. Referred pain to the right
shoulder occurs via the phrenic nerve (C3-C5) irritation from diaphragmatic
inflammation. A positive Murphy's sign (inspiratory arrest during deep palpation
of the RUQ) indicates gallbladder inflammation. Ultrasound confirming gallstones
with gallbladder wall thickening (greater than 4 mm) and pericholecystic fluid
confirms acute cholecystitis.
Q4. A 68-year-old male presents with exertional substernal chest pressure
relieved
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,by rest. He has a history of hypertension and hyperlipidemia. His ECG shows
inverted T waves in leads V4-V6. What is the most appropriate initial
pharmacologic therapy?
A) Sublingual nitroglycerin PRN
B) Warfarin 5 mg daily
C) Metoprolol succinate daily
D) Amlodipine 10 mg daily
Answer: C
Rationale: Beta-blockers such as metoprolol succinate are first-line therapy for
chronic stable angina. They reduce myocardial oxygen demand by decreasing
heart
rate, contractility, and blood pressure, thereby prolonging diastole and
improving coronary perfusion. This reduces the frequency and severity of angina
episodes. Sublingual nitroglycerin is indicated for acute symptom relief rather
than daily management. Warfarin is not indicated for stable angina unless atrial
fibrillation or another specific indication exists. Amlodipine is an alternative
therapy but is not first-line for exertional angina.
Q5. You auscultate a harsh, crescendo-decrescendo systolic murmur at the right
upper sternal border that radiates to the carotids. The patient reports syncope
during exertion. What is the most likely diagnosis?
A) Mitral regurgitation
B) Aortic stenosis
C) Pulmonic stenosis
D) Ventricular septal defect
Answer: B
Rationale: Aortic stenosis produces a characteristic harsh, crescendo-decrescendo
(diamond-shaped) systolic ejection murmur best heard at the right upper sternal
border (aortic area). The murmur radiates to the carotids and may be
accompanied
by a palpable thrill. The classic triad of aortic stenosis is angina, syncope,
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, and dyspnea. Syncope during exertion occurs because the fixed obstruction
prevents adequate cardiac output increase during exercise, leading to cerebral
hypoperfusion. This is a serious finding requiring prompt evaluation.
Q6. A patient with bulging cheeks often described as "chipmunk" facies likely has
which of the following diseases?
A) Mumps
B) Cushing's syndrome
C) Acromegaly
D) Bell's palsy
Answer: A
Rationale: Bulging cheeks or "chipmunk" facies is a classic presentation of
mumps, which causes inflammation and swelling of the parotid glands. The
parotid
glands are located bilaterally in the cheeks just anterior and inferior to the
ears. The swelling is often bilateral and gives the characteristic appearance.
Cushing's syndrome presents with moon facies (rounding of the face due to fat
deposition) rather than bulging cheeks specifically. Acromegaly presents with
coarsening of facial features, prognathism (protruding jaw), and enlargement of
the hands and feet. Bell's palsy presents with unilateral facial droop.
Q7. In a patient with suspected acute pericarditis, which of the following physical
exam findings is most characteristic?
A) Pericardial friction rub
B) S3 gallop
C) S4 gallop
D) Midsystolic click
Answer: A
Rationale: A pericardial friction rub is the hallmark physical exam finding in
acute pericarditis. It is a high-pitched, scratching or grating sound that is best
heard with the diaphragm of the stethoscope at the left lower sternal border. The
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