★ ★ ★ NEET SS 2026 EXAM PREPARATION ★ ★ ★
CARDIOLOGY
MASTERY
120 HIGH-YIELD MCQs
WITH FULL EXPLANATIONS, GUIDELINE & TRIAL REFERENCES
Super-Specialty Entrance Preparation | Feeder: General Medicine
WHAT'S INSIDE THIS BOOK
✔ 120 Clinical-Vignette MCQs Across 14 Cardiology Topics
✔ Simple, Easy-to-Follow Language — No Jargon Overload
✔ Detailed Explanation for EVERY Option (Correct + Incorrect)
✔ Backed by Landmark Trials & Latest ESC / ACC-AHA Guidelines
✔ Real Exam Marking Pattern: +4 Correct / −1 Incorrect
Topics: HFrEF • HFpEF • ACS/CAD • Arrhythmias & EP • Valvular Disease •
Cardiomyopathies • Adult CHD • Pericardial Disease • Hypertension •
Pulmonary Hypertension • Endocarditis • Aortic Disease • Devices & EP • Prevention
Designed for NEET SS Cardiology Aspirants — 2026
, TABLE OF CONTENTS
14 Sections — 120 Questions
1. Heart Failure with Reduced Ejection Fraction (HFrEF).................................Q1–12
2. Heart Failure with Preserved Ejection Fraction (HFpEF)..........................Q13–20
3. Acute Coronary Syndrome & Coronary Artery Disease...............................Q21–35
4. Arrhythmias & Electrophysiology.....................................................................Q36–50
5. Valvular Heart Disease..........................................................................................Q51–62
6. Cardiomyopathies...................................................................................................Q63–72
7. Adult Congenital Heart Disease..........................................................................Q73–80
8. Pericardial Disease.................................................................................................Q81–86
9. Systemic Hypertension..........................................................................................Q87–92
10. Pulmonary Hypertension...................................................................................Q93–98
11. Infective Endocarditis........................................................................................Q99–104
12. Diseases of the Aorta........................................................................................Q105–110
13. Cardiac Devices & EP Procedures..................................................................Q111–115
14. Preventive Cardiology & Lipids....................................................................Q116–120
, WELCOME
Let's get you exam-ready!
Hi there! This book is built for one purpose: helping you clear NEET SS Cardiology with confidence.
Every question here is written like a real clinical case — the kind you'll see in the actual exam. We've
kept the explanations simple and easy to follow, without cutting corners on accuracy. If a term sounds
complicated, we explain it in plain words right next to it.
HOW TO USE THIS BOOK
1. Read the case carefully — age, symptoms, exam findings, and test results all matter.
2. Pick your answer — before looking at the solution.
3. Read ALL FOUR explanations — not just the correct one — that's where the real learning
happens.
4. Note the guideline or trial — examiners love asking “which trial proved this?”
MARKING PATTERN
+4 for Correct • −1 for Incorrect (matches the real exam pattern)
Good luck — let's get you exam-ready!
, Section 1: Heart Failure with Reduced Ejection Fraction
(HFrEF)
Q1.
A 58-year-old man with ischemic cardiomyopathy (EF 28%) has been on carvedilol, enalapril,
and spironolactone at full doses for 3 months. He’s still short of breath on moderate exertion
(NYHA class II). BP 118/74, HR 68/min, potassium 4.6, kidney function normal.
What should be done next?
A. Add digoxin B. Switch enalapril to sacubitril-valsartan (after a 36-hour gap) C. Add
ivabradine D. Refer for a CRT device
Select the SINGLE best answer.
Correct Answer: B
Explanation (in simple terms): Sacubitril-valsartan is a combination drug (called an ARNI)
that works better than a plain ACE inhibitor once someone is already on good background
therapy. Because he’s still symptomatic despite three good drugs, guidelines say: swap the ACE
inhibitor for an ARNI. You must leave a 36-hour gap between stopping the ACE inhibitor and
starting the ARNI, otherwise there’s a real risk of a dangerous swelling reaction called
angioedema.
Why the others are wrong: - A. Digoxin — helps reduce hospital visits but doesn’t reduce
risk of death, and it’s not the first thing you add before optimizing the “big four” drugs. - C.
Ivabradine — only used when heart rate is 70/min or higher despite full beta-blocker dose.
His heart rate is 68, so it doesn’t apply. - D. CRT — needs a wide QRS complex (≥130 ms) on
ECG. We aren’t told his QRS is wide, so we can’t jump to this.
Guideline/Trial: PARADIGM-HF trial; 2022 ACC/AHA/HFSA Heart Failure Guidelines.
Q2.
A 64-year-old woman is newly diagnosed with HFrEF (EF 30%), non-ischemic cause. She has
diabetes, mildly reduced kidney function, and normal BP. Her doctor wants to start her on all
four major HFrEF drug classes: beta-blocker, ARNI, MRA (like spironolactone), and an SGLT2
inhibitor.
What is the current best-practice approach to starting these four drugs?
CARDIOLOGY
MASTERY
120 HIGH-YIELD MCQs
WITH FULL EXPLANATIONS, GUIDELINE & TRIAL REFERENCES
Super-Specialty Entrance Preparation | Feeder: General Medicine
WHAT'S INSIDE THIS BOOK
✔ 120 Clinical-Vignette MCQs Across 14 Cardiology Topics
✔ Simple, Easy-to-Follow Language — No Jargon Overload
✔ Detailed Explanation for EVERY Option (Correct + Incorrect)
✔ Backed by Landmark Trials & Latest ESC / ACC-AHA Guidelines
✔ Real Exam Marking Pattern: +4 Correct / −1 Incorrect
Topics: HFrEF • HFpEF • ACS/CAD • Arrhythmias & EP • Valvular Disease •
Cardiomyopathies • Adult CHD • Pericardial Disease • Hypertension •
Pulmonary Hypertension • Endocarditis • Aortic Disease • Devices & EP • Prevention
Designed for NEET SS Cardiology Aspirants — 2026
, TABLE OF CONTENTS
14 Sections — 120 Questions
1. Heart Failure with Reduced Ejection Fraction (HFrEF).................................Q1–12
2. Heart Failure with Preserved Ejection Fraction (HFpEF)..........................Q13–20
3. Acute Coronary Syndrome & Coronary Artery Disease...............................Q21–35
4. Arrhythmias & Electrophysiology.....................................................................Q36–50
5. Valvular Heart Disease..........................................................................................Q51–62
6. Cardiomyopathies...................................................................................................Q63–72
7. Adult Congenital Heart Disease..........................................................................Q73–80
8. Pericardial Disease.................................................................................................Q81–86
9. Systemic Hypertension..........................................................................................Q87–92
10. Pulmonary Hypertension...................................................................................Q93–98
11. Infective Endocarditis........................................................................................Q99–104
12. Diseases of the Aorta........................................................................................Q105–110
13. Cardiac Devices & EP Procedures..................................................................Q111–115
14. Preventive Cardiology & Lipids....................................................................Q116–120
, WELCOME
Let's get you exam-ready!
Hi there! This book is built for one purpose: helping you clear NEET SS Cardiology with confidence.
Every question here is written like a real clinical case — the kind you'll see in the actual exam. We've
kept the explanations simple and easy to follow, without cutting corners on accuracy. If a term sounds
complicated, we explain it in plain words right next to it.
HOW TO USE THIS BOOK
1. Read the case carefully — age, symptoms, exam findings, and test results all matter.
2. Pick your answer — before looking at the solution.
3. Read ALL FOUR explanations — not just the correct one — that's where the real learning
happens.
4. Note the guideline or trial — examiners love asking “which trial proved this?”
MARKING PATTERN
+4 for Correct • −1 for Incorrect (matches the real exam pattern)
Good luck — let's get you exam-ready!
, Section 1: Heart Failure with Reduced Ejection Fraction
(HFrEF)
Q1.
A 58-year-old man with ischemic cardiomyopathy (EF 28%) has been on carvedilol, enalapril,
and spironolactone at full doses for 3 months. He’s still short of breath on moderate exertion
(NYHA class II). BP 118/74, HR 68/min, potassium 4.6, kidney function normal.
What should be done next?
A. Add digoxin B. Switch enalapril to sacubitril-valsartan (after a 36-hour gap) C. Add
ivabradine D. Refer for a CRT device
Select the SINGLE best answer.
Correct Answer: B
Explanation (in simple terms): Sacubitril-valsartan is a combination drug (called an ARNI)
that works better than a plain ACE inhibitor once someone is already on good background
therapy. Because he’s still symptomatic despite three good drugs, guidelines say: swap the ACE
inhibitor for an ARNI. You must leave a 36-hour gap between stopping the ACE inhibitor and
starting the ARNI, otherwise there’s a real risk of a dangerous swelling reaction called
angioedema.
Why the others are wrong: - A. Digoxin — helps reduce hospital visits but doesn’t reduce
risk of death, and it’s not the first thing you add before optimizing the “big four” drugs. - C.
Ivabradine — only used when heart rate is 70/min or higher despite full beta-blocker dose.
His heart rate is 68, so it doesn’t apply. - D. CRT — needs a wide QRS complex (≥130 ms) on
ECG. We aren’t told his QRS is wide, so we can’t jump to this.
Guideline/Trial: PARADIGM-HF trial; 2022 ACC/AHA/HFSA Heart Failure Guidelines.
Q2.
A 64-year-old woman is newly diagnosed with HFrEF (EF 30%), non-ischemic cause. She has
diabetes, mildly reduced kidney function, and normal BP. Her doctor wants to start her on all
four major HFrEF drug classes: beta-blocker, ARNI, MRA (like spironolactone), and an SGLT2
inhibitor.
What is the current best-practice approach to starting these four drugs?
