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NU 578 Pharmacology 2026/2027 – Unit 4 GI Drugs Complete Study Guide with Verified Q&A & Rationales

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This complete study guide is specifically designed for the NU 578 Pharmacology for Advanced Practice Nurses Unit 4 exam at the University of South Alabama, offering a focused collection of exam-aligned questions and answers for the 2026/2027 academic year . This comprehensive resource covers all essential GI pharmacology topics assessed in Unit 4, including acid-suppression therapy (PPIs, H2 receptor antagonists, antacids), prokinetic agents (metoclopramide, erythromycin), laxatives and stool softeners (bulk-forming, stimulant, osmotic), antidiarrheals (loperamide, diphenoxylate/atropine, bismuth subsalicylate), antiemetics (ondansetron, prochlorperazine, aprepitant, metoclopramide), and agents for inflammatory bowel disease (5-ASA compounds, corticosteroids, immunomodulators, anti-TNF therapy) . Each question is paired with verified answers and detailed rationales to strengthen clinical reasoning, reinforce pharmacologic principles, and ensure thorough preparation for this critical exam . Developed exclusively for MSN, DNP, and APRN students in advanced pharmacology courses at the University of South Alabama, this complete study guide serves as the ultimate tool for comprehensive exam readiness . By engaging with these exam-aligned practice questions and studying the accompanying rationales, students can systematically evaluate their knowledge, pinpoint strengths and weaknesses, and build the confidence necessary to succeed on the Unit 4 GI pharmacology examination. This resource is vital for mastering pharmacotherapy of the gastrointestinal system and advancing academic and clinical progress in graduate nursing programs. Vertical Keywords NU 578 Unit 4 GI Pharmacology Study Guide Advanced Practice Nursing Pharmacology Gastrointestinal Drug Therapy GERD and PUD Treatment Prokinetic Agents Antiemetic Drugs IBD Pharmacotherapy University of South Alabama Nursing APRN Pharmacology Exam Prep Verified NU 578 Answers GI Drugs Unit Exam Readiness

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UNIVERSITY OF SOUTH ALABAMA — COLLEGE OF NURSING




NU 578 Pharmacology
Unit 4 GI Drugs Complete
Study Guide
Gastrointestinal Pharmacology Practice Questions



Topic Focus: PUD/GERD, Antacids, H2 Blockers, PPIs, Antidiarrheals, Laxatives,
Antiemetics, & IBD


Edition 1 · August 2026 · All Questions Complete




Table of Contents

1. Instructions for Use 2

2. PUD/GERD & Acid Suppression (Questions 1–25) 2

3. H2 Receptor Antagonists (Questions 26–40) 4

4. Proton Pump Inhibitors (Questions 41–55) 5

,5. Antacids & Mucosal Protectants (Questions 56–70) 6

6. Antidiarrheals & IBS Drugs (Questions 71–90) 7

7. Laxatives & Constipation (Questions 91–105) 8

8. Antiemetics & Nausea (Questions 106–120) 9

9. IBD & C. diff (Questions 121–130) 10


NU 578 Pharmacology Page 1

, NU 578 PHARMACOLOGY STUDY GUIDE PUD/GERD — Q1–25




How to Use This Guide
Read each stem, choose your answer, then check the rationale directly below it. The correct
option is marked, and each wrong option is explained so you understand why it's wrong — not
just that it is. All questions are derived directly from the source material and verified for
accuracy.



Category: PUD/GERD & Acid Suppression — Questions 1–25


1 What is the main treatment goal for PUD/GERD?

A Neutralization of stomach acid
B Eradication of H. pylori
C Promotion of gastric emptying
D Protection of the gastric mucosa only


Why A is correct: The main treatment goal for PUD and GERD is neutralization or reduction
of stomach acid to allow healing of mucosal damage and prevent further injury.

B — Eradication of H. pylori is important but not the main goal for all cases.
C — Promotility agents address symptoms but acid neutralization is primary.
D — Mucosal protection is supportive but not the primary goal.

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