D027 ADVANCED PATHOPHARMACOLOGICAL
FOUNDATIONS QUESTIONS WITH 100%
ACCURATE ANSWERS
What organ does cystic fibrosis affect? - Accurate answers Affects the pancreas causing
secretions into the lungs
What is Klinefelter syndrome? - Accurate answers An extra X chromosome for males so
example XXY causing female-like qualities
What is Turner Syndrome? - Accurate answers females. missing or deformed x
chromosome. right hemisphere dysfunction, hearing loss, ear infection, language and
articulation disorders, visual spatial and attentional problems
What is beta thalassemia? - Accurate answers a condition in which the synthesis of the
beta-globin chains is decreased or absent. Causes low hemoglobin.
Which medication is contraindicated in a patient with Beta Thalassemia? - Accurate answers
Ferrous Sulfate
What drug is used in combination with other agent to treat lymphoid tissue (leukemia). Directly
toxic to lymphoid tissues Selective estrogen receptor modulators (SERM) - for hormone
receptor positive and advanced breast cancer. (Tomaxafin - reduces risk and recurrence risk) -
Accurate answers Glucocorticoids
What is the normal ejection fraction? - Accurate answers 55-60%. Less than 50% is BAD
Is an ejection fraction of 50% reduced or preserved? - Accurate answers Preserved
What are symptoms of left sided heart failure? - Accurate answers Think PULMONARY.
JVD, FVO, rails, S3 murmurs. Number one cause of right sided heart failure!
What are symptoms of right sided heart failure? - Accurate answers Think peripheral
vascular. Lower extremity edema, abdominal distension.
What is the gold standard lab test for heart failure? - Accurate answers BNP. Heart failure
is a result greater than 100
What heart disease is worse with exertion? - Accurate answers Ischemic heart disease
because the demand requirements are higher.
, What should you assess before giving Digoxin? - Accurate answers Apical pulse
How should Warfarin be started? - Accurate answers Start initial dose at half to monitor
the effects
What causes the destruction of alveolar walls? Air goes in but can't get out which leads to
hyperinflation - Accurate answers Emphysema
What causes excess mucus production and smooth muscle hypertrophy? - Accurate answers
Bronchitis
What is a chronic inflammatory obstruction of bronchi? - Accurate answers Asthma,
Triggers cause mucus to clog bronchial tubes.
What causes an overbite and buffalo hump? - Accurate answers Endocrine disorder called
acromegaly (overproduction of growth hormone)
What causes Addison's disease? - Accurate answers Decreased glucocorticoid (due to
autoimmune destruction of adrenal cortex)
What causes Cushing's syndrome? - Accurate answers excess cortisol
What causes Grave's disease? - Accurate answers overproduction of thyroid hormone.
HYPERthyroidism.
When should you instruct the patient to take their FIRST dose of antihypertensive? - Accurate
answers At night to avoid orthostatic hypotension. Educate slow position changes and lay
down if needed.
What are side effects of ACE inhibitors? - Accurate answers dry cough
angioedema
hyperkalemia
*Contraindicated in pregnancy
Which type of antihypertensive should NOT be given to patients with Asthma? - Accurate
answers Nonselective beta blocker (-lol) because both beta-2 receptors are effected
What is the first choice of calcium channel blocker? - Accurate answers Verapamil
What side effect should you watch for in a patient taking a statin drug? - Accurate answers
Muscle pain which can lead to rhabdomyolysis, kidney failure, and death.
Which diuretic is NOT used in patients with kidney failure and sickle cell disease? - Accurate
answers Thiazide diuretics
FOUNDATIONS QUESTIONS WITH 100%
ACCURATE ANSWERS
What organ does cystic fibrosis affect? - Accurate answers Affects the pancreas causing
secretions into the lungs
What is Klinefelter syndrome? - Accurate answers An extra X chromosome for males so
example XXY causing female-like qualities
What is Turner Syndrome? - Accurate answers females. missing or deformed x
chromosome. right hemisphere dysfunction, hearing loss, ear infection, language and
articulation disorders, visual spatial and attentional problems
What is beta thalassemia? - Accurate answers a condition in which the synthesis of the
beta-globin chains is decreased or absent. Causes low hemoglobin.
Which medication is contraindicated in a patient with Beta Thalassemia? - Accurate answers
Ferrous Sulfate
What drug is used in combination with other agent to treat lymphoid tissue (leukemia). Directly
toxic to lymphoid tissues Selective estrogen receptor modulators (SERM) - for hormone
receptor positive and advanced breast cancer. (Tomaxafin - reduces risk and recurrence risk) -
Accurate answers Glucocorticoids
What is the normal ejection fraction? - Accurate answers 55-60%. Less than 50% is BAD
Is an ejection fraction of 50% reduced or preserved? - Accurate answers Preserved
What are symptoms of left sided heart failure? - Accurate answers Think PULMONARY.
JVD, FVO, rails, S3 murmurs. Number one cause of right sided heart failure!
What are symptoms of right sided heart failure? - Accurate answers Think peripheral
vascular. Lower extremity edema, abdominal distension.
What is the gold standard lab test for heart failure? - Accurate answers BNP. Heart failure
is a result greater than 100
What heart disease is worse with exertion? - Accurate answers Ischemic heart disease
because the demand requirements are higher.
, What should you assess before giving Digoxin? - Accurate answers Apical pulse
How should Warfarin be started? - Accurate answers Start initial dose at half to monitor
the effects
What causes the destruction of alveolar walls? Air goes in but can't get out which leads to
hyperinflation - Accurate answers Emphysema
What causes excess mucus production and smooth muscle hypertrophy? - Accurate answers
Bronchitis
What is a chronic inflammatory obstruction of bronchi? - Accurate answers Asthma,
Triggers cause mucus to clog bronchial tubes.
What causes an overbite and buffalo hump? - Accurate answers Endocrine disorder called
acromegaly (overproduction of growth hormone)
What causes Addison's disease? - Accurate answers Decreased glucocorticoid (due to
autoimmune destruction of adrenal cortex)
What causes Cushing's syndrome? - Accurate answers excess cortisol
What causes Grave's disease? - Accurate answers overproduction of thyroid hormone.
HYPERthyroidism.
When should you instruct the patient to take their FIRST dose of antihypertensive? - Accurate
answers At night to avoid orthostatic hypotension. Educate slow position changes and lay
down if needed.
What are side effects of ACE inhibitors? - Accurate answers dry cough
angioedema
hyperkalemia
*Contraindicated in pregnancy
Which type of antihypertensive should NOT be given to patients with Asthma? - Accurate
answers Nonselective beta blocker (-lol) because both beta-2 receptors are effected
What is the first choice of calcium channel blocker? - Accurate answers Verapamil
What side effect should you watch for in a patient taking a statin drug? - Accurate answers
Muscle pain which can lead to rhabdomyolysis, kidney failure, and death.
Which diuretic is NOT used in patients with kidney failure and sickle cell disease? - Accurate
answers Thiazide diuretics
