2026 NCLEX-RN All-in-One Next
Generation Practice Questions with
Clinical Rationales
## SET 1: FUNDAMENTALS & SAFETY (Questions 1-30)
### Question 1
A home health nurse is caring for a child who has Lyme disease. Which
action is appropriate?
A) Ensure state health department notification
B) Administer antitoxin
C) Educate family to avoid sharing personal belongings
D) Assess for skin necrosis
**Correct Answer: A**
,**Rationale:** Lyme disease is a reportable communicable disease in
most states. Antitoxin is not used; antibiotics are the treatment. Lyme
disease is not spread person-to-person. Erythema migrans is the classic
rash, not skin necrosis.
---
### Question 2
A nurse notices fraying on the electrical cord of a client's continuous
passive motion (CPM) device. What should the nurse do FIRST?
A) Initiate requisition for replacement
B) Report defect to maintenance staff
C) Remove the device from the room
D) Ensure inspection sticker is current
**Correct Answer: C**
**Rationale:** Client safety is the priority. A frayed cord poses
immediate fire and electrocution hazards. Remove the device
immediately, then follow up with reporting and replacement.
---
,### Question 3
A nurse is setting up a sterile field for wound irrigation. Which action is
correct when pouring sterile solution?
A) Remove cap and place sterile-side up on clean surface
B) Place sterile gauze over spilled solution areas
C) Hold bottle in center of sterile field when pouring
D) Hold bottle with label facing away from palm
**Correct Answer: A**
**Rationale:** The cap should be removed and placed with the sterile
side up on a clean surface. Spilled solution should be discarded and the
field reestablished if contaminated. Pour solution into a sterile
receptacle, not from the center of the field. Label should face the palm
when pouring to avoid drips contaminating the label.
---
### Question 4
A client with expressive aphasia and right hemiparesis after a stroke
requires communication support. What promotes communication
among staff?
, A) Posting swallow precautions at head of bed
B) Noting changes in treatment plan in medical record
C) Recording progress in nurse's note
D) Regular interdisciplinary team meetings
**Correct Answer: D**
**Rationale:** Regular interdisciplinary team meetings ensure
consistent, coordinated communication about the client's
communication needs and strategies among all caregivers.
---
### Question 5
A nurse is performing postmortem care prior to family visit. Which
action should the nurse take?
A) Cross patient's arms across chest
B) Hold client's eyes shut for a few seconds
C) Place client in high Fowler's position
D) Remove dentures from mouth
**Correct Answer: B**
Generation Practice Questions with
Clinical Rationales
## SET 1: FUNDAMENTALS & SAFETY (Questions 1-30)
### Question 1
A home health nurse is caring for a child who has Lyme disease. Which
action is appropriate?
A) Ensure state health department notification
B) Administer antitoxin
C) Educate family to avoid sharing personal belongings
D) Assess for skin necrosis
**Correct Answer: A**
,**Rationale:** Lyme disease is a reportable communicable disease in
most states. Antitoxin is not used; antibiotics are the treatment. Lyme
disease is not spread person-to-person. Erythema migrans is the classic
rash, not skin necrosis.
---
### Question 2
A nurse notices fraying on the electrical cord of a client's continuous
passive motion (CPM) device. What should the nurse do FIRST?
A) Initiate requisition for replacement
B) Report defect to maintenance staff
C) Remove the device from the room
D) Ensure inspection sticker is current
**Correct Answer: C**
**Rationale:** Client safety is the priority. A frayed cord poses
immediate fire and electrocution hazards. Remove the device
immediately, then follow up with reporting and replacement.
---
,### Question 3
A nurse is setting up a sterile field for wound irrigation. Which action is
correct when pouring sterile solution?
A) Remove cap and place sterile-side up on clean surface
B) Place sterile gauze over spilled solution areas
C) Hold bottle in center of sterile field when pouring
D) Hold bottle with label facing away from palm
**Correct Answer: A**
**Rationale:** The cap should be removed and placed with the sterile
side up on a clean surface. Spilled solution should be discarded and the
field reestablished if contaminated. Pour solution into a sterile
receptacle, not from the center of the field. Label should face the palm
when pouring to avoid drips contaminating the label.
---
### Question 4
A client with expressive aphasia and right hemiparesis after a stroke
requires communication support. What promotes communication
among staff?
, A) Posting swallow precautions at head of bed
B) Noting changes in treatment plan in medical record
C) Recording progress in nurse's note
D) Regular interdisciplinary team meetings
**Correct Answer: D**
**Rationale:** Regular interdisciplinary team meetings ensure
consistent, coordinated communication about the client's
communication needs and strategies among all caregivers.
---
### Question 5
A nurse is performing postmortem care prior to family visit. Which
action should the nurse take?
A) Cross patient's arms across chest
B) Hold client's eyes shut for a few seconds
C) Place client in high Fowler's position
D) Remove dentures from mouth
**Correct Answer: B**
