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Pharmacology Case Study PDF | Nursing Medication Analysis & Clinical Application Study Guide

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Pharmacology Case Study PDF is a comprehensive nursing study resource designed to help students apply pharmacology concepts to real-world patient care scenarios. This case study material supports understanding of medications, drug classifications, therapeutic effects, adverse reactions, nursing interventions, and clinical decision-making. Ideal for nursing, healthcare, and pharmacology students, this resource helps strengthen medication knowledge and improve the ability to analyze patient cases using evidence-based pharmacology principles.

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I. Patient Profile

Samantha Hasting is a 32-year-old female presenting to the emergency department with

severe lower abdominal pain and vaginal bleeding for 3 hours. The patient was admitted to ER

and given a pregnancy test which was positive. Bedside ultrasound shows a 24–25-week

gestation. Patient denies previous knowledge of pregnancy with no prior prenatal care. Patient

states she has had gas for the past 2 months that she now believes could have been fetal

movement. Past medical history shows uncontrolled type 1 diabetes, chronic hypertension,

preeclampsia in previous pregnancy, substance abuse (heroin), atrial fibrillation, hepatis C,

depression, previous cesarean 3 years ago. Patient has 9 previous pregnancies, 3 children, 2

spontaneous abortions and 3 medical abortions.

Ultrasound shows, single live fetus along with placenta previa and free fluid in the

abdomen. Urine drug screen is positive for methadone and cannabinoids. Vital signs are unstable:

BP- 162/98, HR- 118, RR-24, TEMP- 38.5C/101.3F, SpO2 94% on room air. Patient is anxious,

pale and diaphoretic. Upon examination eyes show conjunctival pallor with dry mucous

membranes. Patient is tachycardic with 2+ pitting edema in lower extremities and tachypneic

with clear auscultation. Abdomen tender upon palpitation with positive rebound tenderness and

positive pregnancy. Cervix appears closed on examination, but active vaginal bleeding is present.

Patient is alert and oriented x4 with no focal deficits. Diagnostic testing was completed as

follows.

Lab Results:

 CBC: Hgb 9.2 g/DL, WBC 16.5 x 10 ^9/L, Platelets 90 x 10^9/L

 BMP: Na 134 mEq/L, K 3.3 mEq/L, Cr 1.4 mg/dL, Glucose 210 mg/dL




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 LFTs: AST 80 U/L, ALT 75 U/L, Total Bilirubin 1.8 mg/dL

 Urinalysis: 3+ protein, 2+ leukocytes, 1+ blood

 Urine Drug Screen: Positive for methadone and cannabinoids

 Bedside ultrasound: single live fetus, placenta previa, free fluid in

abdomen.

Medications:

 Insulin

 Methadone 80 mg PO qd

 Sertraline 100 mg PO qd

 Omeprazole 20 mg PO qd

 Eliquis 5 mg BID

o Allergies: penicillin (anaphylaxis), latex (severe rash), Haldol

(anaphylaxis).

Patient is currently homeless, staying at multiple shelters and has limited social support.

All living children are currently in foster care. Patient reports to be an active 1 pack per day

smoker, occasional alcohol user, and substance user (methadone and heroin). Patient is to be

admitted to Labor and Delivery for urgent maternal-fetal evaluation and management.

II: Pharmacological Analysis

 Methadone: 80 mg PO daily.

o Methadone is used as opioid detoxification, and it works by binding with opioid

receptors in the central nervous system which alters the perception and emotional

response to pain.




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