NRl 568/l NR568l Midterml Exam:l
Advancedl Pharmacologyl forl thel
AGPCNPl Reviewl (Latestl 2026/l 2027l
Update)l |l Qsl &l As|l Gradel A|l 100%l
Correctl (Verifiedl Answers)-l Chamberlain
QUESTION
Urinaryl retentionl medication
Answer:
Selectivel alpha-1l adrenergicl antagonistl -l Tamsulosin
QUESTION
cholinergicl treatmentl ofl urinaryl retention
Answer:
muscarinicl blockadel inl thel urinaryl tractl canl causel urinaryl hesitancyl orl retention.l Withl
someonel whol wasl catheterizedl canl treatl withl al muscarinicl agonist.l Nausea,l diarrhea,l
sweating,l bradycardia,l bronchoconstrictionl (avoidl inl asthma/COPD).
QUESTION
Treatmentl ofl UTIl inl pregnancy,l includingl dose
Answer:
UTIsl mustl bel treatedl asl complicatedl infectionsl inl pregnancy:l Firstl linel treatment
-Trimethoprim/sulfamethoxazolel 160/800l mgl bidl 7-14l days
-Nitrofurantoinl isl contraindicatedl inl thel thirdl trimesterl ofl pregnancyl otherwisel 100mgl
BIDl forl 5l days
QUESTION
,Treatmentl ofl dysurial associatedl withl UTI
Answer:
ol phenazopyridinel -l providesl symptomaticl relief
l Willl discolorl urinel tol al reddishl orange;l oral,l 100mgl tol 200l mgl takel TID
QUESTION
phenazopyridinel -l contraindication/teaching
Answer:
§l Contraindicatedl inl clientsl withl severel renall insufficiency
§l Don'tl takel forl morel thanl 2l days,l willl stainl clothes,l bodyl fluids
QUESTION
Treatmentl ofl UTIl inl patientsl withl chronicl kidneyl disease,l withl dose
Answer:
§l Amoxicillinl 500l mgl POl TIDl forl 7l daysl isl thel studyl guide'sl bestl choicel forl
uncomplicatedl UTIl inl CKDl (CrCll 25l mL/min)—monitoringl hypersensitivityl reactionl
ensuresl safety
QUESTION
Treatmentl ofl UTIl inl patientsl withl ckdl optionl 2
Answer:
Nitrofurantoinl 100l mgl POl BIDl xl 5l days:l Contraindicatedl withl CrCll <60l mL/minl
(studyl guide:l contraindicatedl ifl CrCll <60)—riskl ofl toxicity
Bactericidal,l concentratesl inl urine—monitorl pulmonaryl reactionsl duel tol rarel butl seriousl
risk
QUESTION
monitorl nitrofurantoinl sidel effects
Answer:
,pulmonaryl reaction,l hepatotoxicity,l peripherall neuropathy,l hemolyticl anemia,l dermatologicl
reaction
QUESTION
nitrofurantoinl andl pregnancy
Answer:
Pregnancyl contraindicatedl inl 3rdl trimesterl d/tl hemolyticl anemia
QUESTION
monitorl Trimethopriml sulfamethoxazolel inl uti
Answer:
§l hyperkalemia,l hematologicl effects,l nephrotoxicity,l SJSl orl TENS,l INRl increasesl withl
warfarin,l watchl INR
·l Categoryl Dl forl pregnancyl -l folatel antagonisml teratogenicl inl 1stl trimesterl andl
kernicterusl riskl inl 3rd.
Inhibitsl folatel synthesis—monitorl hyperkalemia,l especiallyl inl CKD
QUESTION
Amoxicillinl forl UTI
Answer:
watchl forl hypersensitivityl (primaryl concern),l GIl effects,l neurotoxicity,l renall function,
·l Safel inl pregnancyl monitorl forl hypersensitivity
·l CKDl safel butl adjustl dose
QUESTION
Treatmentl ofl hyperkalemia
Answer:
K-binderl (sodiuml polystyrenel sulfonate)l syntheticl cationl exchangel resinl thatl doesl al nal
andl Kl exchangel inl thel intestine.l Bindsl withl Kl inl thel colonl andl eliminatesl inl feces.
, QUESTION
Treatmentl ofl hyperphosphatemia
Answer:
ol Calciuml acetatel (PhosLol -l phosphatel binder)l ESRD.l Takenl withl meds.l monitorl
tetany,l restrictl foodsl inl dairy,l hydrate
QUESTION
Managementl ofl drugsl usedl tol treatl anemial inl chronicl kidneyl disease
Answer:
ol Epoetinl alfal -l stimulatesl ironl uptakel andl hemel biosynthesisl inl erythroidl precursors.l
Givenl inl CKDl withl Hgbl lessl thanl 9-10l g/dL.
QUESTION
·l Monitoringl drugsl prescribedl tol treatl hypercalcemia
Answer:
Calcimimeticl agentl Cinacalcetl MOAl isl tol decreasel seruml parathyroidl hormonel (PTH)l
secondaryl tol CKDl andl seruml calcium.l Reducingl PTHl andl lowerl seruml calcium.l
Cinacalcetl canl causel nauseal vomiting,l hypocalcemia.l Monitorl CYP3A4l (grapefruitl juice).
QUESTION
treatl Chlamydia
Answer:
Doxycyclinel 100l mgl BIDl forl 7l days;l ORl alternativel Azithromycinl 1gl singlel dose;l
levofloxacinl 500l mgl pol oncel dailyl forl 7l days
QUESTION
Gonorrheal treatment
Answer:
Advancedl Pharmacologyl forl thel
AGPCNPl Reviewl (Latestl 2026/l 2027l
Update)l |l Qsl &l As|l Gradel A|l 100%l
Correctl (Verifiedl Answers)-l Chamberlain
QUESTION
Urinaryl retentionl medication
Answer:
Selectivel alpha-1l adrenergicl antagonistl -l Tamsulosin
QUESTION
cholinergicl treatmentl ofl urinaryl retention
Answer:
muscarinicl blockadel inl thel urinaryl tractl canl causel urinaryl hesitancyl orl retention.l Withl
someonel whol wasl catheterizedl canl treatl withl al muscarinicl agonist.l Nausea,l diarrhea,l
sweating,l bradycardia,l bronchoconstrictionl (avoidl inl asthma/COPD).
QUESTION
Treatmentl ofl UTIl inl pregnancy,l includingl dose
Answer:
UTIsl mustl bel treatedl asl complicatedl infectionsl inl pregnancy:l Firstl linel treatment
-Trimethoprim/sulfamethoxazolel 160/800l mgl bidl 7-14l days
-Nitrofurantoinl isl contraindicatedl inl thel thirdl trimesterl ofl pregnancyl otherwisel 100mgl
BIDl forl 5l days
QUESTION
,Treatmentl ofl dysurial associatedl withl UTI
Answer:
ol phenazopyridinel -l providesl symptomaticl relief
l Willl discolorl urinel tol al reddishl orange;l oral,l 100mgl tol 200l mgl takel TID
QUESTION
phenazopyridinel -l contraindication/teaching
Answer:
§l Contraindicatedl inl clientsl withl severel renall insufficiency
§l Don'tl takel forl morel thanl 2l days,l willl stainl clothes,l bodyl fluids
QUESTION
Treatmentl ofl UTIl inl patientsl withl chronicl kidneyl disease,l withl dose
Answer:
§l Amoxicillinl 500l mgl POl TIDl forl 7l daysl isl thel studyl guide'sl bestl choicel forl
uncomplicatedl UTIl inl CKDl (CrCll 25l mL/min)—monitoringl hypersensitivityl reactionl
ensuresl safety
QUESTION
Treatmentl ofl UTIl inl patientsl withl ckdl optionl 2
Answer:
Nitrofurantoinl 100l mgl POl BIDl xl 5l days:l Contraindicatedl withl CrCll <60l mL/minl
(studyl guide:l contraindicatedl ifl CrCll <60)—riskl ofl toxicity
Bactericidal,l concentratesl inl urine—monitorl pulmonaryl reactionsl duel tol rarel butl seriousl
risk
QUESTION
monitorl nitrofurantoinl sidel effects
Answer:
,pulmonaryl reaction,l hepatotoxicity,l peripherall neuropathy,l hemolyticl anemia,l dermatologicl
reaction
QUESTION
nitrofurantoinl andl pregnancy
Answer:
Pregnancyl contraindicatedl inl 3rdl trimesterl d/tl hemolyticl anemia
QUESTION
monitorl Trimethopriml sulfamethoxazolel inl uti
Answer:
§l hyperkalemia,l hematologicl effects,l nephrotoxicity,l SJSl orl TENS,l INRl increasesl withl
warfarin,l watchl INR
·l Categoryl Dl forl pregnancyl -l folatel antagonisml teratogenicl inl 1stl trimesterl andl
kernicterusl riskl inl 3rd.
Inhibitsl folatel synthesis—monitorl hyperkalemia,l especiallyl inl CKD
QUESTION
Amoxicillinl forl UTI
Answer:
watchl forl hypersensitivityl (primaryl concern),l GIl effects,l neurotoxicity,l renall function,
·l Safel inl pregnancyl monitorl forl hypersensitivity
·l CKDl safel butl adjustl dose
QUESTION
Treatmentl ofl hyperkalemia
Answer:
K-binderl (sodiuml polystyrenel sulfonate)l syntheticl cationl exchangel resinl thatl doesl al nal
andl Kl exchangel inl thel intestine.l Bindsl withl Kl inl thel colonl andl eliminatesl inl feces.
, QUESTION
Treatmentl ofl hyperphosphatemia
Answer:
ol Calciuml acetatel (PhosLol -l phosphatel binder)l ESRD.l Takenl withl meds.l monitorl
tetany,l restrictl foodsl inl dairy,l hydrate
QUESTION
Managementl ofl drugsl usedl tol treatl anemial inl chronicl kidneyl disease
Answer:
ol Epoetinl alfal -l stimulatesl ironl uptakel andl hemel biosynthesisl inl erythroidl precursors.l
Givenl inl CKDl withl Hgbl lessl thanl 9-10l g/dL.
QUESTION
·l Monitoringl drugsl prescribedl tol treatl hypercalcemia
Answer:
Calcimimeticl agentl Cinacalcetl MOAl isl tol decreasel seruml parathyroidl hormonel (PTH)l
secondaryl tol CKDl andl seruml calcium.l Reducingl PTHl andl lowerl seruml calcium.l
Cinacalcetl canl causel nauseal vomiting,l hypocalcemia.l Monitorl CYP3A4l (grapefruitl juice).
QUESTION
treatl Chlamydia
Answer:
Doxycyclinel 100l mgl BIDl forl 7l days;l ORl alternativel Azithromycinl 1gl singlel dose;l
levofloxacinl 500l mgl pol oncel dailyl forl 7l days
QUESTION
Gonorrheal treatment
Answer:
