NRl 566/l NR566l Midterml Exam:l
Advancedl Pharmacologyl forl Carel ofl thel
Familyl Guidel (Latestl 2026/l 2027l Update)l
|l Qsl &l As|l Gradel A|l 100%l Correctl
(Verifiedl Answers)-l Chamberlain
QUESTION
Carbapenemsl MOA
Answer:
-ex:l imipeneml
-bindsl tol 2l penicillinl bindingl proteins-->l weakeningl ofl bacteriall celll wall-->l celll lysisl
andl death
QUESTION
Carbapenemsl Dosel adjustment
Answer:
-dosel adjustmentl inl olderl adultsl w/l decreasedl renall fxn
QUESTION
Carbanpenemsl elimination
Answer:
-renal
QUESTION
Vancomycinl MOA
,Answer:
-inhibitsl celll walll synthesis-->l bacteriall lysisl &l death
QUESTION
Vancol cl diff
Answer:
-initiall tx:l txl w/l orall vancomycin
-mild-mod:l 125mgl POl QID
-fluminant:l 125mgl PRl QID
-severe:l pulsedl dosel xl 10days
-recurrencel C-diff:l pulsedl vancol regimenl w/l tapering
QUESTION
Vancol adversel effects
Answer:
-renall toxicity
QUESTION
vancol providerl responsel tol adversel effects
Answer:
-troughl levelsl
-ifl kidneyl damagel occursl (increasel Crl byl 50%)-->l reducel vancol dose
QUESTION
cephalosporinl structure
Answer:
QUESTION
,Tetracyclinesl MOA
Answer:
Inhibitsl proteinl synthesisl byl bindingl tol 30Sl ribosomall subunit-->l inhl bitsl bindingl ofl
transferl RNAl tol mRNA
QUESTION
Tetracyclinesl ptl education
Answer:
-dol notl takel w/l calciuml supplements/milk,l irons,l mgl laxatives,l orl mostl antacids
-avoidl sunl exposure
QUESTION
tetracyclinesl effectsl inl preg
Answer:
suppressesl thel growthl ofl longl bonesl inl prematurel infants
-reversiblel ifl d/c
QUESTION
macrolidesl adversel effects
Answer:
QTl prolongationl
GIl effects
QUESTION
clindamycinl MOA
Answer:
-bindsl tol thel 50Sl subunitl ofl bacteriall ribosomes-->l inhibitingl proteinl synthesis
, QUESTION
clindamycinl therapeuticl indication
Answer:
-gram+l coccil
-alternativel tol penicillinsl
-anaerobicl infectionsl outsidel ofl thel CNS
-Groupl Al strepl infectionl
-gasl gangrenel (C.l perfringens)
QUESTION
clindamycinl ptl education
Answer:
-reportl diarrheal (c.l diff)
QUESTION
clindamycinl drugl interaction
Answer:
decreasesl orall contraceptives
QUESTION
pencillins:l bacteriall resistance
Answer:
-3l factors:l 1)inabilityl ofl drugl tol reachl target,l 2)inactivationl ofl penicillinsl byl bacteriall
enzymesl 3)productionl ofl pencillinl bindingl proteinsl thatl havel lowl affinityl forl penicllins
QUESTION
Penicillinl Vl vsl Penicillinl G
Answer:
-bothl narrowl spectruml penicillins
Advancedl Pharmacologyl forl Carel ofl thel
Familyl Guidel (Latestl 2026/l 2027l Update)l
|l Qsl &l As|l Gradel A|l 100%l Correctl
(Verifiedl Answers)-l Chamberlain
QUESTION
Carbapenemsl MOA
Answer:
-ex:l imipeneml
-bindsl tol 2l penicillinl bindingl proteins-->l weakeningl ofl bacteriall celll wall-->l celll lysisl
andl death
QUESTION
Carbapenemsl Dosel adjustment
Answer:
-dosel adjustmentl inl olderl adultsl w/l decreasedl renall fxn
QUESTION
Carbanpenemsl elimination
Answer:
-renal
QUESTION
Vancomycinl MOA
,Answer:
-inhibitsl celll walll synthesis-->l bacteriall lysisl &l death
QUESTION
Vancol cl diff
Answer:
-initiall tx:l txl w/l orall vancomycin
-mild-mod:l 125mgl POl QID
-fluminant:l 125mgl PRl QID
-severe:l pulsedl dosel xl 10days
-recurrencel C-diff:l pulsedl vancol regimenl w/l tapering
QUESTION
Vancol adversel effects
Answer:
-renall toxicity
QUESTION
vancol providerl responsel tol adversel effects
Answer:
-troughl levelsl
-ifl kidneyl damagel occursl (increasel Crl byl 50%)-->l reducel vancol dose
QUESTION
cephalosporinl structure
Answer:
QUESTION
,Tetracyclinesl MOA
Answer:
Inhibitsl proteinl synthesisl byl bindingl tol 30Sl ribosomall subunit-->l inhl bitsl bindingl ofl
transferl RNAl tol mRNA
QUESTION
Tetracyclinesl ptl education
Answer:
-dol notl takel w/l calciuml supplements/milk,l irons,l mgl laxatives,l orl mostl antacids
-avoidl sunl exposure
QUESTION
tetracyclinesl effectsl inl preg
Answer:
suppressesl thel growthl ofl longl bonesl inl prematurel infants
-reversiblel ifl d/c
QUESTION
macrolidesl adversel effects
Answer:
QTl prolongationl
GIl effects
QUESTION
clindamycinl MOA
Answer:
-bindsl tol thel 50Sl subunitl ofl bacteriall ribosomes-->l inhibitingl proteinl synthesis
, QUESTION
clindamycinl therapeuticl indication
Answer:
-gram+l coccil
-alternativel tol penicillinsl
-anaerobicl infectionsl outsidel ofl thel CNS
-Groupl Al strepl infectionl
-gasl gangrenel (C.l perfringens)
QUESTION
clindamycinl ptl education
Answer:
-reportl diarrheal (c.l diff)
QUESTION
clindamycinl drugl interaction
Answer:
decreasesl orall contraceptives
QUESTION
pencillins:l bacteriall resistance
Answer:
-3l factors:l 1)inabilityl ofl drugl tol reachl target,l 2)inactivationl ofl penicillinsl byl bacteriall
enzymesl 3)productionl ofl pencillinl bindingl proteinsl thatl havel lowl affinityl forl penicllins
QUESTION
Penicillinl Vl vsl Penicillinl G
Answer:
-bothl narrowl spectruml penicillins
