NRl 565/l NR565l Midterml Exam:l
Advancedl Pharmacologyl Fundamentalsl
Reviewl (Latestl 2026/l 2027l Update)l |l Qsl
&l As|l Gradel A|l 100%l Correctl (Verifiedl
Answers)-l Chamberlain
QUESTION
Avoidl w/l HF
Answer:
CCB-->l decreasel myocardiall contractility->l decreasel CO
QUESTION
Avoidl w/l AVl heartl block
Answer:
betal blockers/CCB-->l suppressl AVl conduction-->l worseningl heatyl block
QUESTION
Avoidl w/l CAD
Answer:
hydralazine-->l reflexl tachycardia-->l anginall attack
QUESTION
Avoidl w/l postl MI
Answer:
hydralazine-->l reflexl tachycardia-->l increasedl cardiacl work/oxygenl demand
,QUESTION
Drugsl forl HRl 5
Answer:
1.l diureticsl
2.l ACE-I
3.l Betal blockers
4.l sodium-glucosel cotransporterl 2l inhibitorsl
5.l Dig
QUESTION
Rangel forl Digoxin
Answer:
0.5-0.8
QUESTION
Classificationl ofl antidysrhythmicl drugsl 5
Answer:
Classl I:l sodiuml channell blockersl (procainamide,l lidocaine)
Classl II:l betal blockers
Classl III:l potassiuml channell blockersl (amio)
Classl IV:l calciuml channell blockers
Classl 5:l Dig
QUESTION
Sodiuml Channell blockers
Answer:
Antiarrhythmicl medicationsl thatl slowl conductionl throughl thel heartl byl blockingl sodiuml
channels
,QUESTION
Betal blockers
Answer:
reducel calciuml entryl &l depressl stagel 4l depolarization
QUESTION
Potassiuml channell blockers
Answer:
blockl potassiuml channels-->l delayl repolarizationl ofl fastl potentials
QUESTION
Propranolol
Answer:
non-selectivel betal blocker
affectsl bothl betal inl heart/lungs
cautionl w/l asthmaticl pts
QUESTION
Amiol complications
Answer:
-thyroidl toxicityl (hyper/hypo)
-liverl toxicityl
-opticl neuropathy/neuritis/l blindnessl
-skinl reactionsl
-avoidl grapefruitl juice
QUESTION
Drugsl thatl lowerl LDLl 4
, Answer:
HMG-CoAl reductasel inhibitorsl (statins)l
bilel acidl sequestrantsl (colesevelam)
monoclonall antibodiesl
ezetimibe
QUESTION
Ezetimibe
Answer:
-reducesl plasmal cholesteroll
-actsl onl cellsl inl smalll intestinesl tol inhibitl dietaryl cholesteroll
-adjunctl tol dietl mods
-adversel effects:l liverl damage/l increasel bile-->l gallstones
QUESTION
Statinsl inl pregnancy
Answer:
contraindicated
QUESTION
PCSK9l inhibitors
Answer:
-i.e.l alirocumab/evolocumab
l -MOA:l proteinl thatl bindsl tol LDLl receptorsl inl thel liver-->l decreasel LDL
-Pharmacokentics:l subq
-Adversel Effects:l riskl ofl developingl antibodiesl (immunogenicity)
QUESTION
Gemfibrozill andl warfarin
Answer:
Advancedl Pharmacologyl Fundamentalsl
Reviewl (Latestl 2026/l 2027l Update)l |l Qsl
&l As|l Gradel A|l 100%l Correctl (Verifiedl
Answers)-l Chamberlain
QUESTION
Avoidl w/l HF
Answer:
CCB-->l decreasel myocardiall contractility->l decreasel CO
QUESTION
Avoidl w/l AVl heartl block
Answer:
betal blockers/CCB-->l suppressl AVl conduction-->l worseningl heatyl block
QUESTION
Avoidl w/l CAD
Answer:
hydralazine-->l reflexl tachycardia-->l anginall attack
QUESTION
Avoidl w/l postl MI
Answer:
hydralazine-->l reflexl tachycardia-->l increasedl cardiacl work/oxygenl demand
,QUESTION
Drugsl forl HRl 5
Answer:
1.l diureticsl
2.l ACE-I
3.l Betal blockers
4.l sodium-glucosel cotransporterl 2l inhibitorsl
5.l Dig
QUESTION
Rangel forl Digoxin
Answer:
0.5-0.8
QUESTION
Classificationl ofl antidysrhythmicl drugsl 5
Answer:
Classl I:l sodiuml channell blockersl (procainamide,l lidocaine)
Classl II:l betal blockers
Classl III:l potassiuml channell blockersl (amio)
Classl IV:l calciuml channell blockers
Classl 5:l Dig
QUESTION
Sodiuml Channell blockers
Answer:
Antiarrhythmicl medicationsl thatl slowl conductionl throughl thel heartl byl blockingl sodiuml
channels
,QUESTION
Betal blockers
Answer:
reducel calciuml entryl &l depressl stagel 4l depolarization
QUESTION
Potassiuml channell blockers
Answer:
blockl potassiuml channels-->l delayl repolarizationl ofl fastl potentials
QUESTION
Propranolol
Answer:
non-selectivel betal blocker
affectsl bothl betal inl heart/lungs
cautionl w/l asthmaticl pts
QUESTION
Amiol complications
Answer:
-thyroidl toxicityl (hyper/hypo)
-liverl toxicityl
-opticl neuropathy/neuritis/l blindnessl
-skinl reactionsl
-avoidl grapefruitl juice
QUESTION
Drugsl thatl lowerl LDLl 4
, Answer:
HMG-CoAl reductasel inhibitorsl (statins)l
bilel acidl sequestrantsl (colesevelam)
monoclonall antibodiesl
ezetimibe
QUESTION
Ezetimibe
Answer:
-reducesl plasmal cholesteroll
-actsl onl cellsl inl smalll intestinesl tol inhibitl dietaryl cholesteroll
-adjunctl tol dietl mods
-adversel effects:l liverl damage/l increasel bile-->l gallstones
QUESTION
Statinsl inl pregnancy
Answer:
contraindicated
QUESTION
PCSK9l inhibitors
Answer:
-i.e.l alirocumab/evolocumab
l -MOA:l proteinl thatl bindsl tol LDLl receptorsl inl thel liver-->l decreasel LDL
-Pharmacokentics:l subq
-Adversel Effects:l riskl ofl developingl antibodiesl (immunogenicity)
QUESTION
Gemfibrozill andl warfarin
Answer:
