ATI Pharmacology Proctored Examination
2026–2027 | Complete 100-Question Practice
Exam with Detailed Rationales, Medication
Safety, Antidotes, Pharmacokinetics, NGN
Clinical Judgment & NCLEX Pharmacology
Mastery Review
ATI Pharmacology Proctored Examination
Comprehensive Pharmacology Practice Examination
Features
✔ 100 ATI Pharmacology-Style Questions
✔ Detailed Rationales
✔ Medication Safety & Administration
✔ Pharmacokinetics & Pharmacodynamics
✔ Cardiovascular Medications
✔ Respiratory Medications
✔ Endocrine Medications
✔ Neurological & Psychiatric Medications
✔ Antimicrobials
✔ Oncology & Immune System Agents
✔ Delegation & Prioritization
✔ NGN Clinical Judgment Concepts
Examination Blueprint
1. Medication Safety & Administration – 10 Questions
2. Pharmacokinetics & Pharmacodynamics – 10 Questions
,3. Cardiovascular Medications – 15 Questions
4. Respiratory Medications – 10 Questions
5. Endocrine Medications – 15 Questions
6. Neurological & Psychiatric Medications – 15 Questions
7. Antimicrobial Therapy – 10 Questions
8. Oncology & Immune System Medications – 5 Questions
9. Prioritization, Delegation & Clinical Judgment – 10 Questions
, Questions 1–100
Medication Safety and Administration
1. A nurse is preparing to administer medications to a client. Which action
demonstrates adherence to the rights of medication administration?
A. Administering medications without verifying the client's identity
B. Comparing the medication label with the medication administration record (MAR) before
administration
C. Delegating medication administration to unlicensed personnel
D. Administering medications prepared by another nurse
Correct Answer: B. Comparing the medication label with the medication
administration record (MAR) before administration
Rationale: Verification of the medication against the MAR helps ensure the correct
medication is administered safely.
ATI Success Strategy: Follow all medication rights consistently to reduce medication errors.
Difficulty: Easy
2. A nurse is preparing to administer digoxin. Which assessment finding requires
withholding the medication and notifying the provider?
A. Apical pulse of 52/min
B. Blood pressure of 128/76 mm Hg
C. Respiratory rate of 18/min
D. Temperature of 37°C (98.6°F)
Correct Answer: A. Apical pulse of 52/min
Rationale: Digoxin can worsen bradycardia. The medication should be withheld when the
pulse is below the prescribed parameter.
ATI Success Strategy: Assess the apical pulse for one full minute before administering
digoxin.
Difficulty: Moderate
, 3. A nurse is preparing to administer insulin lispro. When should the medication be
administered?
A. 1 hour before meals
B. At bedtime
C. Within 15 minutes of a meal
D. 4 hours before meals
Correct Answer: C. Within 15 minutes of a meal
Rationale: Lispro is a rapid-acting insulin and should be administered immediately before
food intake to prevent hypoglycemia.
ATI Success Strategy: Know insulin onset, peak, and duration times.
Difficulty: Moderate
4. A nurse is administering intravenous potassium chloride. Which action is
appropriate?
A. Administer by IV push
B. Dilute and infuse using a pump
C. Infuse undiluted
D. Administer over 5 minutes
Correct Answer: B. Dilute and infuse using a pump
Rationale: Potassium chloride must be diluted and administered slowly to prevent fatal
cardiac dysrhythmias.
ATI Success Strategy: Potassium is never administered by IV push.
Difficulty: Moderate
5. A nurse is preparing to administer warfarin. Which laboratory value should the
nurse review?
A. INR
B. Serum amylase
C. Sodium level
D. Calcium level
Correct Answer: A. INR
Rationale: INR is used to monitor the anticoagulant effect of warfarin therapy.
2026–2027 | Complete 100-Question Practice
Exam with Detailed Rationales, Medication
Safety, Antidotes, Pharmacokinetics, NGN
Clinical Judgment & NCLEX Pharmacology
Mastery Review
ATI Pharmacology Proctored Examination
Comprehensive Pharmacology Practice Examination
Features
✔ 100 ATI Pharmacology-Style Questions
✔ Detailed Rationales
✔ Medication Safety & Administration
✔ Pharmacokinetics & Pharmacodynamics
✔ Cardiovascular Medications
✔ Respiratory Medications
✔ Endocrine Medications
✔ Neurological & Psychiatric Medications
✔ Antimicrobials
✔ Oncology & Immune System Agents
✔ Delegation & Prioritization
✔ NGN Clinical Judgment Concepts
Examination Blueprint
1. Medication Safety & Administration – 10 Questions
2. Pharmacokinetics & Pharmacodynamics – 10 Questions
,3. Cardiovascular Medications – 15 Questions
4. Respiratory Medications – 10 Questions
5. Endocrine Medications – 15 Questions
6. Neurological & Psychiatric Medications – 15 Questions
7. Antimicrobial Therapy – 10 Questions
8. Oncology & Immune System Medications – 5 Questions
9. Prioritization, Delegation & Clinical Judgment – 10 Questions
, Questions 1–100
Medication Safety and Administration
1. A nurse is preparing to administer medications to a client. Which action
demonstrates adherence to the rights of medication administration?
A. Administering medications without verifying the client's identity
B. Comparing the medication label with the medication administration record (MAR) before
administration
C. Delegating medication administration to unlicensed personnel
D. Administering medications prepared by another nurse
Correct Answer: B. Comparing the medication label with the medication
administration record (MAR) before administration
Rationale: Verification of the medication against the MAR helps ensure the correct
medication is administered safely.
ATI Success Strategy: Follow all medication rights consistently to reduce medication errors.
Difficulty: Easy
2. A nurse is preparing to administer digoxin. Which assessment finding requires
withholding the medication and notifying the provider?
A. Apical pulse of 52/min
B. Blood pressure of 128/76 mm Hg
C. Respiratory rate of 18/min
D. Temperature of 37°C (98.6°F)
Correct Answer: A. Apical pulse of 52/min
Rationale: Digoxin can worsen bradycardia. The medication should be withheld when the
pulse is below the prescribed parameter.
ATI Success Strategy: Assess the apical pulse for one full minute before administering
digoxin.
Difficulty: Moderate
, 3. A nurse is preparing to administer insulin lispro. When should the medication be
administered?
A. 1 hour before meals
B. At bedtime
C. Within 15 minutes of a meal
D. 4 hours before meals
Correct Answer: C. Within 15 minutes of a meal
Rationale: Lispro is a rapid-acting insulin and should be administered immediately before
food intake to prevent hypoglycemia.
ATI Success Strategy: Know insulin onset, peak, and duration times.
Difficulty: Moderate
4. A nurse is administering intravenous potassium chloride. Which action is
appropriate?
A. Administer by IV push
B. Dilute and infuse using a pump
C. Infuse undiluted
D. Administer over 5 minutes
Correct Answer: B. Dilute and infuse using a pump
Rationale: Potassium chloride must be diluted and administered slowly to prevent fatal
cardiac dysrhythmias.
ATI Success Strategy: Potassium is never administered by IV push.
Difficulty: Moderate
5. A nurse is preparing to administer warfarin. Which laboratory value should the
nurse review?
A. INR
B. Serum amylase
C. Sodium level
D. Calcium level
Correct Answer: A. INR
Rationale: INR is used to monitor the anticoagulant effect of warfarin therapy.
