Pathophysiology: pain
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, Pathophysiology: pain
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1. What are some causes of pain? Infection, ischemia, tissue necrosis, stretching of tis-
sue, chemicals or burns
2. Causes of pain in skeletal muscle? Ischemia or hemorrhage
3. Stomach and intestine pain results femur inflammation of the mucosa, ischemia, disten-
from? tion or muscle spasms
4. somatic pain arises from? skin (cutaneous), bone or muscle (conducted by sen-
sory nerves)
5. Where does visceral pain originate Originates in the organs and travels by sympathetic
and how does it travel? fibers
6. What is a marker of short term pain? reflex withdrawal (ex: hand involuntarily jerking away
from hot stove)
7. Markers of long term pain? Continuous pain (swelling or inflammation present)
8. What are nociceptors? Pain receptors, free sensory nerve endings that are
present in most tissues of the body
9. What are stimulates nociceptors? Thermal, chemical or mechanical/physical means
10. thermal extremes of temperature
11. chemical acids or compounds produced in the body (bradykin-
in, histamine, prostaglandin)
12. Mechanical/physical pressure
13. What is pain threshold? level of stimulation required to activate the nerve end-
ing sufficiently for the individual to perceive pain
14. Constant over time
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