Psoriasis - Pathophysiology
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, Psoriasis - Pathophysiology
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1. Describe Psoria- A chronic auto immune disorder causing excessive skin growth leading to: Red
sis patchy, white-scaly, shedding and itchy symptoms.
Most commonly occurs on:
- Behind knees and elbows
- Face
- Scalp
- Palms
- Feet
2. What is the main Family genetics/history.
risk factor for (e.g. Both parents with psoriasis = 50% risk of developing)
Psoriasis?
3. What age can All ages - Even from infancy
Psoriasis occur? - Most severe form = 16-22 years old
- Stronger onset during childhood
- Milder disease at older onset = 55-60 years old
4. Describe 3 - Hyperproliferations of the epidermis (x10 fold)
pathophysiologi- - Parakeratosis = Incomplete keratinisation of the stratum corneum (SC) = Causing
cal properties of loose and white appearance
Psoriasis - Leading to poor adhesion of SC cells, causing ease of shedding
5. Describe the 1) Psorasis triggered by:
pathogenesis - Environmental factors (e.g. Viral anti-gen presented by antigen presenting cell)
process of - Genetics
Psoriasis
2) T-cells induced (i.e. CD4 Helper T-cell)
- Undergoing clonal expansion -> Enters into blood
3) Activated T-cells migrate to epidermis and dermis
1/5
| Complete Exam Study
Guide, Practice Questions,
Answers & ATI Review
Material
, Psoriasis - Pathophysiology
Study online at https://quizlet.com/_8n2oxv
1. Describe Psoria- A chronic auto immune disorder causing excessive skin growth leading to: Red
sis patchy, white-scaly, shedding and itchy symptoms.
Most commonly occurs on:
- Behind knees and elbows
- Face
- Scalp
- Palms
- Feet
2. What is the main Family genetics/history.
risk factor for (e.g. Both parents with psoriasis = 50% risk of developing)
Psoriasis?
3. What age can All ages - Even from infancy
Psoriasis occur? - Most severe form = 16-22 years old
- Stronger onset during childhood
- Milder disease at older onset = 55-60 years old
4. Describe 3 - Hyperproliferations of the epidermis (x10 fold)
pathophysiologi- - Parakeratosis = Incomplete keratinisation of the stratum corneum (SC) = Causing
cal properties of loose and white appearance
Psoriasis - Leading to poor adhesion of SC cells, causing ease of shedding
5. Describe the 1) Psorasis triggered by:
pathogenesis - Environmental factors (e.g. Viral anti-gen presented by antigen presenting cell)
process of - Genetics
Psoriasis
2) T-cells induced (i.e. CD4 Helper T-cell)
- Undergoing clonal expansion -> Enters into blood
3) Activated T-cells migrate to epidermis and dermis
1/5
