Pathophysiology - Cancer.pdf
Pathophysiology - Cancer
| Complete Exam Study
Guide, Practice Questions,
Answers & ATI Review
Material
, Pathophysiology - Cancer
Pathophysiology - Cancer.pdf
Study online at https://quizlet.com/_hpa495
1. tumor abnormal mass of tissue that results from uncontrolled prolifera-
tion (aka neoplasm)
2. neoplasia abnormal and uncontrolled cell growth (not necessarily cancer)
serving no physiological purpose
3. cancer disease in which abnormal cells divide without control and are able
to invade other tissues
4. carcinoma a cancer arising in the epithelial tissue of the skin or of the lining
of the internal organs.
5. leukemia cancer of blood-forming cells
6. anaplasia loss of differentiation; major characteristic of cancer cells
7. carcinoma in situ (CIS) - pre-invasive epithelial tumors of glandular or squamous cell ori-
gin
- early stage
- localized to the epithelium
-have not penetrated the local basement membrane
8. tumor-suppressor genes Encode for proteins that do 3 things
1. block specific cell cycle phase
2. induce terminal differentiation
3. stimulate cell death
9. caretaker genes - responsible for maintaining genomic integrity
- can be disrupted by mutations, causing chromosomal instability
10. mutagen anything that causes a change in DNA
11. carcinogen anything that causes cancer
Pathophysiology - Cancer
| Complete Exam Study
Guide, Practice Questions,
Answers & ATI Review
Material
, Pathophysiology - Cancer
Pathophysiology - Cancer.pdf
Study online at https://quizlet.com/_hpa495
1. tumor abnormal mass of tissue that results from uncontrolled prolifera-
tion (aka neoplasm)
2. neoplasia abnormal and uncontrolled cell growth (not necessarily cancer)
serving no physiological purpose
3. cancer disease in which abnormal cells divide without control and are able
to invade other tissues
4. carcinoma a cancer arising in the epithelial tissue of the skin or of the lining
of the internal organs.
5. leukemia cancer of blood-forming cells
6. anaplasia loss of differentiation; major characteristic of cancer cells
7. carcinoma in situ (CIS) - pre-invasive epithelial tumors of glandular or squamous cell ori-
gin
- early stage
- localized to the epithelium
-have not penetrated the local basement membrane
8. tumor-suppressor genes Encode for proteins that do 3 things
1. block specific cell cycle phase
2. induce terminal differentiation
3. stimulate cell death
9. caretaker genes - responsible for maintaining genomic integrity
- can be disrupted by mutations, causing chromosomal instability
10. mutagen anything that causes a change in DNA
11. carcinogen anything that causes cancer
