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, Pathophysiology COPD
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1. COPD is a common preventable true
and treatable disease character-
ized by persistent airflow limita-
tion that is not fully reversible
2. COPD weakening and permanent enlargement of the air spaces
distal to the terminal bronchioles, often accompanied by
hypertrophy of the goblet cells and mucus glands
3. COPD is characterized by dyspnea on exertion with significant hypercapnia
4. COPD is 3rd leading cause of death
3rd-7th leading cause of disability
5. copd is underdiagnosed by 60%
6. chronic bronchitis chronic productive cough for 3 months in each of 2 succes-
sive years in a patient in whom other causes of productive
cough have been excluded
7. Emphysema presence of permanent enlargement of the airspaces distal
to the terminal bronchioles, accompanied by destruction of
their walls and without obvious fibrosis
8. copd diseases can overlap true
9. 3 characteristics of COPD progressive dyspnea, chronic cough, chronic tobacco use
10. progressive dyspnea increased WOB, increased RR, sensation of air hunger
11. hypercarbia and hypoxemia = as air gets trapped in the lungs has low levels of O2 and
increased levels of CO2
12. risk factors