NR 565 - advanced
pharmacology midterm -
Chamberlain
2025-2026
Final Exam Questions with
Verified Answers | Grade A+ |
New Version
,CYP450 inducers Speed up metabolism of drugs (drug is cleared faster), drug has lesser effect
(decrease blood levels of drug), elevate CYP450 enzymes
CYP450 inducers pneumonic "Bullshit Crap GPS INDUCES rage"
CYP450 inducer drug names Barbituates, St John wort, Carbamazepine, rifampin, alcohol, phenytoin,
griseofulvin, phenobarbital, sulfonylureas
CYP450 inhibitors inhibit metabolism, increase blood levels of medications
CYP450 pneumonic "VISA credit card debt INHIBITS spending on designers like CK to look GQ"
CYP450 inhibitors drug names Valproate, isoniazid, sulfonamides, amiodarone, chloramphenicol,
ketoconazole, grapefruit juice, quinidine
Physiological changes during pregnancy that impact increase glomerular filtration rate leads to increase durg excretion
pharmacodynamics and pharmacokinetic properties of increase hepatic metabolism
drugs? decrease tone and motility of bowel
increase drug absorption
Examples of medications that can be teratogenic Antiepileptic drugs, antimicrobials such as tetracyclines and fluoroquinolones,
vitamin A in large doses, some anticoagulants, and hormonal medications such
as diethylstilbestrol (DES).
How is absorption of intramuscular medications slow and erratic due to low blood flow in muscles first few days of life
different in neonates?
Why is absorption of medication in the stomach delayed gastric emptying
increased in infancy?
Some medications that should be avoided in the glucocorticoids, discoloration of developing teeth with tetracyclines, and
pediatric patient? kernicterus with sulfonamides, levofloxacin (antibiotics)
aspirin (Severe intoxication from acute overdose)
what should be included in medication administration dosage size and timing
patient education? route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
, What are some things that put the elderly patient at reduced renal function
higher risk for adverse drug reactions? polypharmacy (the use of five or more medications daily)
greater severity of illness
presence of comorbidities
use of drugs that have a low therapeutic index (e.g., digoxin)
increased individual variation secondary to altered pharmacokinetics
inadequate supervision of long-term therapy
poor patient adherence
How can healthcare providers decrease likelihood of obtaining a thorough drug history that includes over-the-counter medications
an elderly patient experiencing an adverse drug considering pharmacokinetic and pharmacodynamics changes due to age
reaction? monitoring the patient's clinical response and plasma drug levels
using the simplest regimen possible
monitoring for drug-drug interactions and iatrogenic illness
periodically reviewing the need for continued drug therapy
encouraging the patient to dispose of old medications
taking steps to promote adherence and to avoid drugs on the Beers list
How can we promote medication adherence with simplifying drug regimens
elderly patients? providing clear and concise verbal and written instructions
using an appropriate dosage form
clearly labeling and dispensing easy-to-open containers
developing daily reminders
monitoring frequently
affordability of drugs
support systems
Why do nitrates need to be taken no later than 4 PM? Need nitrate free interval so tolerance doesn't develop
Nine factors that impact outcome of medication? Gender and race
Genetics and pharmacogenomics
Variability in absorption
placebo effect
Tolerance
patho
age
bodyweight
Do you need informed consent for genetic testing? yes
What is the purpose of the Genetic Information Non- Protects patients from discrimination by employers and insurance providers
Discriminatory Act? based on genetic information
Difference between practice authority and prescriptive Practice authority refers to the nurse practitioner's ability to practice without
authority? physician oversight, whereas prescriptive authority refers to the nurse
practitioner's authority to prescribe medications independently and without
limitations.
pharmacology midterm -
Chamberlain
2025-2026
Final Exam Questions with
Verified Answers | Grade A+ |
New Version
,CYP450 inducers Speed up metabolism of drugs (drug is cleared faster), drug has lesser effect
(decrease blood levels of drug), elevate CYP450 enzymes
CYP450 inducers pneumonic "Bullshit Crap GPS INDUCES rage"
CYP450 inducer drug names Barbituates, St John wort, Carbamazepine, rifampin, alcohol, phenytoin,
griseofulvin, phenobarbital, sulfonylureas
CYP450 inhibitors inhibit metabolism, increase blood levels of medications
CYP450 pneumonic "VISA credit card debt INHIBITS spending on designers like CK to look GQ"
CYP450 inhibitors drug names Valproate, isoniazid, sulfonamides, amiodarone, chloramphenicol,
ketoconazole, grapefruit juice, quinidine
Physiological changes during pregnancy that impact increase glomerular filtration rate leads to increase durg excretion
pharmacodynamics and pharmacokinetic properties of increase hepatic metabolism
drugs? decrease tone and motility of bowel
increase drug absorption
Examples of medications that can be teratogenic Antiepileptic drugs, antimicrobials such as tetracyclines and fluoroquinolones,
vitamin A in large doses, some anticoagulants, and hormonal medications such
as diethylstilbestrol (DES).
How is absorption of intramuscular medications slow and erratic due to low blood flow in muscles first few days of life
different in neonates?
Why is absorption of medication in the stomach delayed gastric emptying
increased in infancy?
Some medications that should be avoided in the glucocorticoids, discoloration of developing teeth with tetracyclines, and
pediatric patient? kernicterus with sulfonamides, levofloxacin (antibiotics)
aspirin (Severe intoxication from acute overdose)
what should be included in medication administration dosage size and timing
patient education? route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
, What are some things that put the elderly patient at reduced renal function
higher risk for adverse drug reactions? polypharmacy (the use of five or more medications daily)
greater severity of illness
presence of comorbidities
use of drugs that have a low therapeutic index (e.g., digoxin)
increased individual variation secondary to altered pharmacokinetics
inadequate supervision of long-term therapy
poor patient adherence
How can healthcare providers decrease likelihood of obtaining a thorough drug history that includes over-the-counter medications
an elderly patient experiencing an adverse drug considering pharmacokinetic and pharmacodynamics changes due to age
reaction? monitoring the patient's clinical response and plasma drug levels
using the simplest regimen possible
monitoring for drug-drug interactions and iatrogenic illness
periodically reviewing the need for continued drug therapy
encouraging the patient to dispose of old medications
taking steps to promote adherence and to avoid drugs on the Beers list
How can we promote medication adherence with simplifying drug regimens
elderly patients? providing clear and concise verbal and written instructions
using an appropriate dosage form
clearly labeling and dispensing easy-to-open containers
developing daily reminders
monitoring frequently
affordability of drugs
support systems
Why do nitrates need to be taken no later than 4 PM? Need nitrate free interval so tolerance doesn't develop
Nine factors that impact outcome of medication? Gender and race
Genetics and pharmacogenomics
Variability in absorption
placebo effect
Tolerance
patho
age
bodyweight
Do you need informed consent for genetic testing? yes
What is the purpose of the Genetic Information Non- Protects patients from discrimination by employers and insurance providers
Discriminatory Act? based on genetic information
Difference between practice authority and prescriptive Practice authority refers to the nurse practitioner's ability to practice without
authority? physician oversight, whereas prescriptive authority refers to the nurse
practitioner's authority to prescribe medications independently and without
limitations.
