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BSN 315 HESI Pharmacology V2 Set 1 & 2 Exam Prep 2026/2027 | Practice Questions | Latest Update

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Prepare for BSN 315 HESI Pharmacology V2 (Set 1 & 2) with this comprehensive review resource featuring original practice questions designed to reinforce essential pharmacology concepts and improve assessment readiness. This review covers pharmacokinetics, pharmacodynamics, medication administration, dosage calculations, adverse drug reactions, drug interactions, cardiovascular medications, respiratory agents, endocrine pharmacology, anti-infectives, pain management, gastrointestinal medications, patient safety, medication education, and evidence-based nursing practice. Ideal for nursing students preparing for HESI assessments, pharmacology coursework, NCLEX-style practice, and clinical application.

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BSN 315 HESI Pharmacology V2 Set 1 & 2 (2026) | Most Tested
Questions & Verified Answers | Latest Update | Graded A+
1. Describe how salicylic acid can lead to systemic toxicity in a patient with
psoriasis.

Salicylic acid is safe and does not cause any systemic effects.

Salicylic acid is primarily used for pain relief and does not cause
toxicity.

Salicylic acid can lead to systemic toxicity when absorbed in
excessive amounts, causing symptoms like tinnitus and
gastrointestinal distress.

Salicylic acid only affects the skin and has no systemic absorption.

2. What is the primary organ affected by acetaminophen overdose that should
be assessed for pain?

Heart

Liver

Kidneys

Lungs

3. A patient prescribed a low-molecular-weight heparin (LMWH) asks why it
requires less frequent laboratory monitoring than heparin. Which information
should the nurse include in the response?

"Low-molecular-weight heparins are less expensive than heparin."

"Low-molecular-weight heparins produce a more predictable
anticoagulant response because of less binding to proteins and
macrophages."

"Low-molecular-weight heparins can be administered orally."

, "Low-molecular-weight heparins come in a single dose that can be
administered to every patient."


4. What is the primary medication used for palliative treatment in cases of
tumor-induced spinal cord compression?

Antidepressants

Corticosteroids

Analgesics

Antibiotics

5. A patient with heart failure is prescribed a beta 1-agonist. What nursing
intervention is most important to monitor after administration?

Respiratory rate

Heart rate and rhythm

Fluid intake and output

Blood glucose levels

6. A nurse is discharging a patient who is getting antibiotic tx. What teaching is
most important?

make sure to limit activity

make sure to take the med on an empty stomach

drink lots of water

take all of the prescribed med even when you're feeling better

7. Describe the importance of patient education when administering
metronidazole for giardiasis.

, Patient education is not necessary as the medication is self-
explanatory.

Patient education is crucial to ensure the client understands the
medication's purpose, potential side effects, and the importance of
completing the full course of treatment.

Patient education only needs to cover the dosage schedule.

Patient education should focus solely on dietary restrictions.

8. Which drug is used for client with tumor induced spinal cord compression

ampicillin

clonidine

dexamethasone

opioid

9. What is the primary action a nurse should take to assess the effectiveness of
antihypertensive medication?

Check the patient's heart rate.

Evaluate the patient's renal function.

Administer a second dose of medication.

Monitor the patient's blood pressure.

10. A client is receiving methylprednisolone 40 mg IV daily. The nurse
anticipates an increase in which lab value as a result of this medication?

RBC

Calcium

Potassium

, Glucose

11. An aphasic patient, who has been receiving meperidine 75 mg every 3-4
hours for pain for the past 36 hours, has suddenly become restless and
irritable. The last dose of meperidine was 4 hours ago. Why is it important for
the nurse to withhold the meperidine, do a complete assessment on the
patient, and contact the prescriber with the findings?

Respiratory depression is imminent

The patient is becoming physiologically dependent on the
meperidine

Tolerance has developed

Toxicity from a metabolite may be occurring

12. The nurse is providing discharge teaching to a client who recently received a
kidney transplant. What is the most severe adverse reaction to cyclosporine
following the kidney transplant?

Fluid in the lung tissue

Susceptibility to infection

An increased temperature

Damage to the new kidney

13. Mitigation therapy with mannitol is used with which of the following?

Bleomycin

Cisplatin

Carmustine

Cyclophosphamide

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