Pathophysiology | Nightingale |
Latest
Question:
Explain the two most common causes of spinal disk herniation
Answer:
-Aging (elderly)
-Obesity
Question:
What level of spinal cord is the most common spinal disk herniation?
Answer:
L4-S1
,Question:
Define Allo-AB vs Auto-AM (alloantibodies vs autoantibodies)
Answer:
Alloantibodies - AB against foreign antigen
Autoantibodies - Against self
Question:
Alloantibodies
Answer:
-Alloantibodies are immune antibodies that are only produced following
exposure to foreign red blood cell antigens.
-They are produced by exposure to foreign red cell antigens which are non-
self antigens but are of the same species.
-Alloantibodies react only with allogenic cells.
-Exposure to alloantigens can occur through pregnancy or transfusion.
, Question:
Autoantibodies
Answer:
-Autoantibodies are antibodies that react with a person's own red blood
cells.
-They can be produced in an autoimmune process and are directed against
one's own red cell antigens.
-Autoantibodies typically react with the patient's own cells and typically all
cells tested.
Question:
Define hemolytic disease of a newborn
Answer:
-most common cause is maternal made antibodies against Rh positive RBC
of the fetus
-Maternal developed alloantibody Rh antigen since Rh antigen negative
from the first encounter
-Now IgG crosses the placenta and attacks all RBCs with Rh antigen on it