4th Edition Study Guide 2026–2027 | Complete Exam Prep,
Chapter Summaries & Practice Questions
All chapters covered
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,Chapter 1. Principles of Pharmacology
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Chapter 2. Structure and Function of the Nervous System
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Chapter 3.Chemical SignalingbyNeurotransmittersandHormones Chapter 4.
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l Methods of Research in Psychopharmacology
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Chapter 5. Catecholamines
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Chapter 6. Serotonin
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Chapter 7. Acetylcholine Chapter
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8.GlutamateandGABA
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Chapter9.DrugAbuseandAddiction Chapter
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l 10. Alcohol
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Chapter 11. The Opioids
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Chapter 12.Psychomotor Stimulants: Cocaine, Amphetamine, andRelated Drugs Chapter
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l 13. Nicotine and Caffeine
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Chapter 14. Marijuana and the Cannabinoids Chapter
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15.Hallucinogens,PCP,andKetamine
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Chapter16. Inhalants, GHB, and Anabolic-Androgenic Steroids
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Chapter 17. DisordersofAnxiety and Impulsivity and the Drugs Used to Treat These Disorders
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Chapter 18. AffectiveDisorders:AntidepressantsandMood Stabilizers
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l Chapter 19. Schizophrenia: Antipsychotic Drugs
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Chapter 20.NeurodegenerativeDiseases
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, Chapter1:PrinciplesofPharmacology l l l l
Multiple Choice l
1. refer(s) to specific molecular changes that occur when a drug binds to a
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l particular target site or receptor, while l l l l l are the resulting widespread
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l alterationsin function. l
a. Drugaction; therapeutic effects
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b. Sideeffects; drug effects
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c. Therapeuticeffects; sideeffects l l l
d. Drugaction; drugeffects l l l
ANSWER:d l
TextbookReference:Pharmacology: TheScience of DrugAction
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2. Afterdrugadministration has occurred, the amount of drugintheblood thatis free
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l tobind at specific target sites is referred to as
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a. thetherapeuticdose.
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b. first-passeffects. l
c. bioavailability.
d. ED50.
ANSWER:c l
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
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3. Thespecific molecular changes that occur when adrugbinds to aparticular target
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l siteor receptor are referred to as
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a. drugeffects. l
b. drugaction. l
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, c. sideeffects.
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d. placeboeffects. l
ANSWER:b l
TextbookReference: Pharmacology: TheScienceofDrugAction
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4. Which ofthefollowing isnot apossible explanation for placebo effects?
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a. Pavlovianconditioning l
b. Geneticvariation l
c. Drugcompetition
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d. Expectation of outcome l l
ANSWER:c l
TextbookReference: Pharmacology: TheScienceofDrugAction
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5. The administration ofoxytocin has been proposedas a treatment for autism.
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a. intravenous
b. oral
c. intranasal
d. intracerebral
ANSWER:c l
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
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6. Whichfactor does not affect thepharmacokinetics of adrug?
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a. Route ofadministration
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b. Lipid solubility
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c. Depot binding l
d. Drugaction l
ANSWER:d l
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
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7. First-pass metabolism occurswhen drugsaretaken l l l l l l
a. orally.
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