MPJE® Exam 2026 | Multistate Pharmacy Jurisprudence
Examination | Questions & Verified Answers
1. A pharmacy sold 1,000 units of a controlled substance in a year. If it
plans to transfer 60 units to another pharmacy, what action must it take
according to the five percent rule?
Register as a distributor
Increase the sales of controlled substances
Notify the DEA
No action needed
2. How frequently must an inventory of controlled substances be
conducted?
at least every 6 months
at least every 3 months
at least every 2 years
at least every year
3. What information must be recorded upon receiving C3-5 substances?
Destroy the invoice immediately after receiving the drugs.
Send the invoice to the DEA for verification.
Record the date the drugs were received and confirm the
order's accuracy.
File the invoice without any additional notes.
4. What is the primary characteristic that differentiates Schedule III drugs
from Schedule I and II drugs?
Low medical use and low potential for abuse
, High abuse potential and severe physical dependence
No medical use and high potential for abuse
Less abuse potential and moderate to low physical
dependence
5. If a pharmacy realizes that a controlled substance prescription was lost
in transit and they do not have the tracking number, what steps should
they take to address the situation?
Dispose of the remaining stock of the controlled substance.
Reissue the prescription without notifying the supplier.
Contact the supplier to report the loss and provide any
available details about the shipment.
Ignore the loss and wait for the prescription to arrive.
6. What is true about controlled substances?
DEA Form 222 must be completed prior to ordering schedule II
controlled substances.
DEA Form 222 must be completed prior to the destruction of a
controlled substance.
DEA Form 41 must be completed prior to transferring schedule II
controlled substances
DEA Form 41 must be completed to report the theft of a
controlled substance.
7. A drug is defined as:
An article intended for use in the diagnosis, cure, mitigation,
treatment, or prevention of disease in man or other animals.
An article recognized in the official USP, HPUS, or NF or any
supplement to any of them.
, All the above
An article (other than food) intended to affect the structure or
any function of the body of man or other animals
8. What is a DEA form-222?
Form required for ordering Schedule II controlled substances
Form required to order schedule I controlled substances
Form required to order all medications
A form for funsies
9. The compounding environment should:
Have adequate space for the orderly placement and storage of
equipment and support materials
Have controlled temperature and lighting
Be kept clean for sanitary reasons and to prevent cross
contamination
None of the above
All of the above
10. If a pharmacy loses its DEA registration certificate, what immediate
action should it take regarding controlled substances?
Continue operations as usual, as the certificate can be replaced
later
Transfer all controlled substances to another pharmacy
Notify patients of the loss and provide refunds
Cease handling controlled substances until re-registered
11. If a compounding pharmacy fails to maintain proper temperature
, controls, what potential impact could this have on the compounded
products?
It would improve the shelf life of the products.
It would have no impact on the products.
It would only affect the packaging of the products.
It could lead to compromised product safety and efficacy.
12. Describe the importance of monitoring environmental factors in the
compounding process.
Monitoring environmental factors ensures product safety and
efficacy by preventing contamination.
Monitoring environmental factors is unnecessary for product
safety.
Monitoring environmental factors is only relevant for large-scale
production.
Monitoring environmental factors only affects the appearance of
the product.
13. Describe the significance of obtaining a separate registration from the
DEA for researchers working with Schedule I drugs.
It provides researchers with unlimited access to all drug
schedules.
It is only necessary for researchers working with Schedule II
drugs.
It allows researchers to bypass state regulations on drug use.
Obtaining a separate registration from the DEA is crucial for
ensuring compliance with federal regulations governing the
use of highly controlled substances.
Examination | Questions & Verified Answers
1. A pharmacy sold 1,000 units of a controlled substance in a year. If it
plans to transfer 60 units to another pharmacy, what action must it take
according to the five percent rule?
Register as a distributor
Increase the sales of controlled substances
Notify the DEA
No action needed
2. How frequently must an inventory of controlled substances be
conducted?
at least every 6 months
at least every 3 months
at least every 2 years
at least every year
3. What information must be recorded upon receiving C3-5 substances?
Destroy the invoice immediately after receiving the drugs.
Send the invoice to the DEA for verification.
Record the date the drugs were received and confirm the
order's accuracy.
File the invoice without any additional notes.
4. What is the primary characteristic that differentiates Schedule III drugs
from Schedule I and II drugs?
Low medical use and low potential for abuse
, High abuse potential and severe physical dependence
No medical use and high potential for abuse
Less abuse potential and moderate to low physical
dependence
5. If a pharmacy realizes that a controlled substance prescription was lost
in transit and they do not have the tracking number, what steps should
they take to address the situation?
Dispose of the remaining stock of the controlled substance.
Reissue the prescription without notifying the supplier.
Contact the supplier to report the loss and provide any
available details about the shipment.
Ignore the loss and wait for the prescription to arrive.
6. What is true about controlled substances?
DEA Form 222 must be completed prior to ordering schedule II
controlled substances.
DEA Form 222 must be completed prior to the destruction of a
controlled substance.
DEA Form 41 must be completed prior to transferring schedule II
controlled substances
DEA Form 41 must be completed to report the theft of a
controlled substance.
7. A drug is defined as:
An article intended for use in the diagnosis, cure, mitigation,
treatment, or prevention of disease in man or other animals.
An article recognized in the official USP, HPUS, or NF or any
supplement to any of them.
, All the above
An article (other than food) intended to affect the structure or
any function of the body of man or other animals
8. What is a DEA form-222?
Form required for ordering Schedule II controlled substances
Form required to order schedule I controlled substances
Form required to order all medications
A form for funsies
9. The compounding environment should:
Have adequate space for the orderly placement and storage of
equipment and support materials
Have controlled temperature and lighting
Be kept clean for sanitary reasons and to prevent cross
contamination
None of the above
All of the above
10. If a pharmacy loses its DEA registration certificate, what immediate
action should it take regarding controlled substances?
Continue operations as usual, as the certificate can be replaced
later
Transfer all controlled substances to another pharmacy
Notify patients of the loss and provide refunds
Cease handling controlled substances until re-registered
11. If a compounding pharmacy fails to maintain proper temperature
, controls, what potential impact could this have on the compounded
products?
It would improve the shelf life of the products.
It would have no impact on the products.
It would only affect the packaging of the products.
It could lead to compromised product safety and efficacy.
12. Describe the importance of monitoring environmental factors in the
compounding process.
Monitoring environmental factors ensures product safety and
efficacy by preventing contamination.
Monitoring environmental factors is unnecessary for product
safety.
Monitoring environmental factors is only relevant for large-scale
production.
Monitoring environmental factors only affects the appearance of
the product.
13. Describe the significance of obtaining a separate registration from the
DEA for researchers working with Schedule I drugs.
It provides researchers with unlimited access to all drug
schedules.
It is only necessary for researchers working with Schedule II
drugs.
It allows researchers to bypass state regulations on drug use.
Obtaining a separate registration from the DEA is crucial for
ensuring compliance with federal regulations governing the
use of highly controlled substances.
