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Exam (elaborations)

GMS 6530 FINAL EXAM

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Exam of 146 pages for the course GMS 6530 at GMS 6530 (GMS 6530 FINAL EXAM)

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sodium channel inactivation


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Na channel activates to open: -70mV
-carry in large current to depolarize cell
-inactivate quickly--while inactive Na+ channel cannot activate at or above
threshold potential
-Na channel undergo fast inactivation by inactivation gate
-Na+ channels undergo slow inactivation which involves conformation
change




hyperlipidemia


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, an increase in plasma lipids in general




leukotriene modifiers


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-released by mast cells (mostly) within minutes
-LTs more potent bronchoconstrictors than histamine and longer duration
of action
---inhibit leukotriene synthesis
---direct leukotriene 4 receptor antagonist




large veins


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larger than 10mm in diameter
-smooth muscle from all three tunics
-thin media with moderate smooth muscle
-venae cavae, pulmonary veins, internal jugular veins, renal veins
-tunica externa is the thickest layer




beta adrenergic antagonists


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Metaprolol

,Ito


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efflux K+ ions
influx of Cl- ions




Does nitroglycerin lead to phosphorylation or Dephosphorylation of myosin light
chain?


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Dephosphorylation




digitalis interactions


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serum potassium (diuretics cause hypokalemia)
hypercalcemia (calcium and digoxin have ionotropic effects)
quinidine, verapamil, amiodarone (decrease renal clearance of digoxin)
hypomagnesmia-sensitizes to arrythmias




Which of the following is a biologic drug that can be used to treat digoxin overdose?


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, Digibind




Emotional states are integrated by the __________, which generates an output that creates
such respiratory variations as laughing and crying.


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PRG




sympathetic control


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nerve fibers innervate renal blood vessels




hypercalecimia


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excess calcium increases heart rate and contraction strength




respiratory system principal organs


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July 30, 2026
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