tPA
Give this one a try later!
- tissue plasminogen activtor
- activates plasminogen to plasmin
Aspirin
Give this one a try later!
- prevents platetet aggregation by irreversible acetylation of COX1 >
inhibits TXA2 in platelets
- lasts life of platelets (7-10 days)
, Warfarin antidotes
Give this one a try later!
- vitamin k (phytonadione)
- FFPs
- transfuse prothrombin complex concentrates
Increase warfarin effects
Give this one a try later!
- phenylbutazone - decrease plasma binding > increasing free (effective)
concentration
- trimethoprim-sulfamethoxazole, metronidazole, fluconazole, amiodarone,
cimetidine, disulfiram > inhibit metabolism > increasing effects
- aspirin & other nsaids > inhibit platelet function
- cephalosporins > eliminate gut bacteria that produce vitamin K
ADP blockers
Give this one a try later!
Give this one a try later!
- tissue plasminogen activtor
- activates plasminogen to plasmin
Aspirin
Give this one a try later!
- prevents platetet aggregation by irreversible acetylation of COX1 >
inhibits TXA2 in platelets
- lasts life of platelets (7-10 days)
, Warfarin antidotes
Give this one a try later!
- vitamin k (phytonadione)
- FFPs
- transfuse prothrombin complex concentrates
Increase warfarin effects
Give this one a try later!
- phenylbutazone - decrease plasma binding > increasing free (effective)
concentration
- trimethoprim-sulfamethoxazole, metronidazole, fluconazole, amiodarone,
cimetidine, disulfiram > inhibit metabolism > increasing effects
- aspirin & other nsaids > inhibit platelet function
- cephalosporins > eliminate gut bacteria that produce vitamin K
ADP blockers
Give this one a try later!
