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A4M ADVANCED MEDICINE REVIEW GUIDE
2026 SOLVED QUESTIONS GRADED A+
◉ What are the functions of testosterone in females? Answer: It
decreases bone deterioration and improve strength of the bone.
It decreases excess body fat.
It elevates Nuro epinephrine in the brain and therefore has an anti-
depressant effect.
It increases muscle mass and strength.
It helps to maintain memory.
It increases muscle tone and prevents skin from sagging.
It increases sense of emotional well-being, self-confidence and
motivation.
It increases sexual interest or libido


◉ What are the signs and symptoms of testosterone deficiency and
females Answer: Anxiety.
Decline and muscle tone, a reduction in HDL, decreased sexual drive,
droopy eyelids, dry skin and poor elasticity, dry and thinning hair,
fatigue, hypersensitivity, and hyper emotional states, a reduction in
dreaming during sleep, loss of pubic care, low self-esteem, mild
depression, muscle wasting, despite proper calorie and protein, intake,
saggy cheeks, thin lips, weight gain

,◉ What are the causes of deficiency of testosterone and females?
Answer: Adrenal stress or burnout
Oral contraceptive use by increasing sex hormone binding globulin.
Chemotherapy
Childbirth
Cholesterol medication
Depression.
Endometriosis.
Aging process.
Psychological trauma.
Surgical menopause


◉ What is the recommended daily dose of testosterone, supplementation
and females? Answer: Dosing must be guided by laboratory testing.
The dosing range is 0.25 mg cream to 4 mg cream daily with the most
common dose being 0.25 mg to 2 mg daily.
Testosterone should always be used transdermally in most situations.
Apply the testosterone to the thigh and rub in for two minutes and rotate
sites.
transference of testosterone can occur for up to 12 hours to humans and
animals when given transdermally


◉ What are the important points to know in administering testosterone
in females during menopause? Answer: There should be a hormone

, holiday: after the patient has been on hormones for six months they will
need to take a hormonal holiday every month. This can be done in
various ways. These are as follows:
The first method is to take all the hormones Monday through Saturday
and then not on Sunday.
The second method is to take all the hormones on days one through 25
and then four days off of all hormones.
If the patient wishes to cycle then have them take all the hormones
including testosterone every day except for progesterone days 14
through 25. This is called mock cycling.


◉ What other sources will cause elevations in serum testosterone levels
Answer: A reduction and core intake.
Exercise.
Good sleep hygiene.
Increasing the amount of protein in the diet.
Weight loss of the patient is overweight
Stress reduction
Taking arginine, loosen or glutamine.
Zinc, supplementation will aid in metabolism of testosterone


◉ What are the important side effects and contraindications of
testosterone therapy and females? Answer: Do not give synthetic
testosterone, also known as methyl testosterone, due to an increase in the
risk of the patient developing liver cancer.

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